A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.
Contents: Interesting Research of the Week, Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.
Interesting Research of the Week
Trace element profiles in pregnant women’s sera and umbilical cord sera and influencing factors: Repeated measurements. [The concentrations of each element between three time points were significantly different; season was an important factor affecting trace element levels.]
Regulations/Policy
Are we speaking the same language? Recommendations for a definition and categorization framework for plastic debris.
Scientific Integrity Issues in Environmental Toxicology and Chemistry: improving research reproducibility, credibility, and transparency.
Using prepared mixtures of ToxCast chemicals to evaluate non-targeted analysis (NTA) method performance.
A high-throughput approach to identify specific neurotoxicants/ developmental toxicants in human neuronal cell function assays.
Reviews
Early-life exposure to endocrine disrupting chemicals associates with childhood obesity.
Water and soil pollution as determinant of water and food quality/contamination and its impact on male fertility.
Epigenetic underpinnings of developmental immunotoxicity and autoimmune disease.
Human Health Studies
BPA/Phenols/Phthalates
Serum concentrations of bisphenol A and its alternatives in elderly population living around e-waste recycling facilities in China: Associations with fasting blood glucose.
Association of cord blood bisphenol A (BPA) with cord blood adiponectin, leptin, fetal growth; adiposity and neoantal complications in a newborn cohort.
Human exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules
Urinary bisphenol A levels in Turkish girls with premature thelarche.
Parabens/Triclosan/Antimicrobials
Prenatal urinary triclosan concentrations and child neurobehavior.
Perfluoroalkyl Substances
Renal function and isomers of perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS): Isomers of C8 Health Project in China.
Arsenic/Metals
Trace Elements Associated with Systemic Lupus Erythematosus and Insulin Resistance.
Toenail-Based Metal Concentrations and Young-Onset Breast Cancer.
Prevalence of rheumatoid arthritis in relation to serum cadmium concentrations: cross-sectional study using Korean National Health and Nutrition Examination Survey (KNHANES) data.
Laboratory Studies
BPA/Phenols
Sex-dependent effects of bisphenol A on type 1 diabetes development in non-obese diabetic (NOD) mice.
Expression of pro-inflammatory cytokines and mediators induced by Bisphenol A via ERK-NFκB and JAK1/2-STAT3 pathways in macrophages.
Computational study suggesting reconsideration of BPA analogues based on their endocrine disrupting potential estimated by binding affinities to nuclear receptors.
Gallic acid protects against bisphenol A-induced alterations in the cardio-renal system of Wistar rats through the antioxidant defense mechanism.
Evaluation of 4-nonylphenol and bisphenol A toxicity using multiple molecular biomarkers in the water flea Daphnia magna.
The endocrine-disrupting potential of four chlorophenols by in vitro and in silico assay.
Toxicological effects of bisphenol A exposure-induced cancer cells migration via activating directly integrin β1.
Bisphenol S induced epigenetic and transcriptional changes in human breast cancer cell line MCF-7.
Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways.
Melatonin attenuates bisphenol A-induced toxicity of the adrenal gland of Wistar rats.
1H NMR-based serum metabolomics analysis of the age-related metabolic effects of perinatal exposure to BPA, BPS, BPF, and BPAF in female mice offspring.
Phthalates
Perinatal phthalate and high-fat diet exposure induce sex-specific changes in adipocyte size and DNA methylation.
Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season.
Di(n-butyl) phthalate exposure impairs meiotic competence and development of mouse oocyte.
Persistent Organic Pollutants
Examining multi- and transgenerational behavioral and molecular alterations resulting from parental exposure to an environmental PCB and PBDE mixture.
The protein expression disorders of connexins (Cx26, Cx32 and Cx43)and keratin 8 in bovine placenta under the influence of DDT, DDE and PCBs.
INTERINDIVIDUAL VARIATION IN THE CYTOCHROME P4501A RESPONSE TO 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN IN HERRING GULL EMBRYO HEPATOCYTES.
Perfluoroalkyl Substances/Organotins
Tributyltin and perfluorooctane sulfonate play a synergistic role in promoting excess fat accumulation in Japanese medaka (Oryzias latipes) via in ovo exposure.
Comparative transcriptomics analysis of the river pufferfish (Takifugu obscurus) by tributyltin exposure: Clues for revealing its toxic injury mechanism.
Flame Retardants
Effects of triphenyl phosphate exposure during fetal development on obesity and metabolic dysfunctions in adult mice: Impaired lipid metabolism and intestinal dysbiosis.
Is the current-use flame retardant, DBE-DBCH, a potential obesogen? Effects on body mass, fat content and associated behaviors in American kestrels.
Pesticides
Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier.
Enantioselectivity in endocrine disrupting effects of four cypermethrin enantiomers based on in vitro models.
Arsenic/Metals
Concentration-dependent effects of mercury and lead on Aβ42: possible implications for Alzheimer’s disease.
Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system.
Bioaccumulation dynamics and gene regulation in a freshwater bivalve after aqueous and dietary exposures to gold nanoparticles and ionic gold.
Exposure to Pb and Cd alters MCT4/CD147 expression and MCT4/CD147-dependent lactate transport in mice Sertoli cells cultured in vitro.
Miscellaneous
The UV filter benzophenone3, alters early follicular assembly in rat whole ovary cultures.
Anandamide down-regulates placental transporter expression through CB2 receptor-mediated inhibition of cAMP synthesis.
Wildlife/Environment/Exposure Studies
BPA/Phenols
Risk characterization of bisphenol-A in the Slovenian population starting from human biomonitoring data.
Temporal and Spatial Distributions of Bisphenol A in Marine and Freshwaters in Turkey.
Several environmental endocrine disruptors in beverages from South China: occurrence and human exposure. [BPA, phthalates, phenols, triclosan, etc]
Phthalates
Environmental distribution and ecotoxicological concerns of phthalic acid esters in creek ecosystem.
Derivation of aquatic life criteria for four phthalate esters and their ecological risk assessment in Liao River.
Persistent Organic Pollutants
Formation and fate of point-source non-extractable DDT-related compounds on their environmental aquatic-terrestrial pathway.
Contaminants in Atlantic walruses in Svalbard Part 1: Relationships between exposure, diet, and pathogen prevalence
Contaminants in Atlantic walruses in Svalbard Part 2: Relationships with endocrine and immune systems.
Estimating missing concentrations of p,p’-DDT in the 1999-2004 National Health and Nutrition Examination Survey using multiple imputation.
Assessment of organochlorine pesticides in the Himalayan riverine ecosystems from Pakistan using passive sampling techniques.
UPTAKE OF HYDROPHOBIC ORGANIC COMPOUNDS, INCLUDING OCPS AND PBDES, AND PERFLUOROALKYL ACIDS (PFAAS) IN FISH AND BLUE CRABS OF THE LOWER PASSAIC RIVER (NJ, USA).
Perfluoroalkyl Substances
Perfluoroalkyl substances in groundwater and home-produced vegetables and eggs around a fluorochemical industrial park in China.
Perfluoroalkyl acids (PFAAs) concentrations and oxidative status in two generations of great tits inhabiting a contamination hotspot.
Determination of 21 perfluoroalkyl substances and organophosphorus compounds in breast milk by liquid chromatography coupled to orbitrap high-resolution mass spectrometry.
Flame Retardants
Temporal trends of polybrominated diphenyl ethers in the sediment cores from different areas in China.
Arsenic/Metals
Biomonitoring of metals and trace elements in urine of central Ethiopian populations.
Influence of an exercise until exhaustion in serum and urinary concentrations of toxic minerals among professional athletes, a preliminary approach.
Spatial distribution of heavy metals and their potential sources in the soil of Yellow River Delta: a traditional oil field in China.
Use of tree rings as a bioindicator to observe atmospheric heavy metal deposition.
Limited effects of changing prey fish communities on food quality for aquatic predators in the eastern Canadian Arctic in terms of essential fatty acids, methylmercury and selenium.
Derogation from drinking water quality standards in Italy according to the European Directive 98/83/EC and the Legislative Decree 31/2001 – a look at the recent past.
Pharmaceuticals
Multi-residue method for the determination of selected veterinary pharmaceutical residues in surface water around Livestock Agricultural farms.
A diverse suite of pharmaceuticals contaminates stream and riparian food webs.
Miscellaneous
Environmental exposure to oestrogenic endocrine disruptors mixtures reflecting on gonadal sex steroids and gametogenesis of the Neotropical fish Astyanax rivularis.
Multiple approaches to surface water quality assessment provide insight for small streams experiencing oil and natural gas development.
Relation of contaminants to fish intersex in riverine sport fishes.
Assessing wild fish exposure to ligands for sex steroid receptors from pulp and paper mill effluents in the Biobio River Basin, Central Chile.
This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.
