Key Publications and Reviews on Endocrine Disrupting Chemicals (EDCs)

Minireview: Endocrine Disruptors: Past Lessons and Future Directions.
Schug TT, Johnson AF, Birnbaum LS, et al.
Mol Endocrinol. 2016 Aug;30(8):833-47. doi: 10.1210/me.2016-1096. Review.
PMID:27477640

A Proposed Framework for the Systematic Review and Integrated Assessment (SYRINA) of Endocrine Disrupting Chemicals.
Vandenberg LN, Ågerstrand M, Beronius A, et al.
Environ Health. 2016 Jul 14;15(1):74. doi: 10.1186/s12940-016-0156-6. Review.
PMID:27412149

Peer-Reviewed and Unbiased Research, Rather than ‘Sound Science’, Should Be Used To Evaluate Endocrine-Disrupting Chemicals.
Trasande L, Vandenberg LN, Bourguignon JP, et al.
J Epidemiol Community Health. 2016
Nov;70(11):1051-1056. doi: 10.1136/jech-2016-207841. Epub 2016 Jul 13. Review.
PMID:27417427

Estimating Burden and Disease Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union.
Trasande L, Zoeller RT, Hass U, et al.
J Clin Endocrinol Metab. 2015 Apr;100(4):1245-55. doi: 10.1210/jc.2014-4324. Epub 2015 Mar 5.
PMID:25742516

Regulatory Decisions on Endocrine Disrupting Chemicals Should Be Based on the Principles of Endocrinology.
Vandenberg LN, Colborn T, Hayes TB, et al.
Reprod Toxicol. 2013 Jul;38:1-15. doi: 10.1016/j.reprotox.2013.02.002. Epub 2013 Feb 11. Review.
PMID:23411111

Designing Endocrine Disruption Out of the Next Generation of Chemicals.
Schug TT, Abagyan R, Blumberg B, et al.
Green Chem. 2013 Jan;15(1):181-198.
PMID:25110461

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses.
Vandenberg LN, Colborn T, Hayes TB, et al.
Endocr Rev. 2012 Jun;33(3):378-455. doi: 10.1210/er.2011-1050.
Epub 2012 Mar 14. Review.
PMID:22419778

Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement
Solecki R, Kortenkamp A, Bergman Å, et al.
 2017 Feb;91(2):1001-1006. doi: 10.1007/s00204-016-1866-9. 
PMID:27714423

Scientific Society Statements on EDCs and Health

EDC-2: The Endocrine Society’s Second Scientific Statement on Endocrine-Disrupting Chemicals
Gore AC, Chappell VA, Fenton SE, et al.
Endocrine Reviews 2015 Dec;36(6):E1-E150. doi: 10.1210/er.2015-1010.
PMID:26544531
Also see:
EDC-2 Executive Summary
The first Endocrine Society Scientific Statement on EDCs (2009)

The International Federation of Gynecology and Obstetrics Opinion on Reproductive Health Impacts of Exposure to Toxic Environmental Chemicals  
Di Renzo GC, Conry JA, Blake J, et al.
 2015 Dec;131(3):219-25. doi: 10.1016/j.ijgo.2015.09.002.
PMID:26433469 

The American College of Obstetricians and Gynecologists: Committee Opinion on Exposure to Toxic Environmental Agents
2013; Reaffirmed 2018

The United Nations: Scientific Knowledge of Endocrine Disrupting Chemicals 
Three reports on EDCs, on identifying EDCs, the environmental effects of EDCs, and global regulatory frameworks.