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Factsheets on Endocrine Disrupting Chemicals

These factsheets were written and produced by HEEDS and other staff at Environmental Health Sciences.

What are EDCs?
Low Doses
Do EDCs Affect Health at Low Doses?
Animal Studies
Are Animal Studies Necessary?
Five Flaws of Chemical Safety Testing
Five Fatal Flaws of Today's Chemical Testing
Do Plastic Additives Harm Human Health?
The Failures of Chemical Recycling

Sources and Further Reading

The Endocrine Society: Endocrine Disrupting Chemicals

Grandjean P. Paracelsus Revisited: The Dose Concept in a Complex World. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):126-32. doi: 10.1111/bcpt.12622.

La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinol. 2020 Jan;16(1):45-57. doi: 10.1038/s41574-019-0273-8.

Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Shioda T, Soto AM, vom Saal FS, Welshons WV, Zoeller RT, Myers JP. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012 Jun;33(3):378-455. doi: 10.1210/er.2011-1050.