EDC Science Weekly, Mar. 11 – 17, 2020 – HEEDS

EDC Science Weekly, Mar. 11 – 17, 2020

Post author:HEEDS
Post published:March 17, 2020
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Regulations/Policy, Methods/Tools/Screening, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies.

Regulations/Policy

Regulatory needs and activities to address the retinoid system in the context of endocrine disruption; the European viewpoint.

A comprehensive analysis of e-waste legislation worldwide.

Methods/Tools/Screening

The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.

FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data.

Computational Toxicology. [accepting articles for a special issue in Chem Res Toxicol]

Reviews

Commentaries/Conference Summaries

Learning from Sisyphus: time to rethink our current, ineffective strategy on neurodevelopmental environmental toxicants.

Accurate science requires that we base our work on accurate publications.

Difficulties in establishing a causal link between chemical exposures and cancer cannot be overcome by court assessments.

BPA/Phenols

Bisphenol A: an emerging threat to female fertility.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Exposure to Dichlorodiphenyldichloroethylene (DDE) and Metallothionein Levels in Rats Fed with Normocaloric or High-Fat Diet: A Review.

Pesticides

An analysis of the setting of the acute reference dose (ARfD) for pesticides in Europe.

Relationship between agrochemical compounds and mammary gland development and breast cancer.

Microplastics

Perspectives and challenges of micro/nano plastics induced toxicity with special reference to phytotoxicity.

Polystyrene nanoparticles: Sources, occurrence in the environment, distribution in tissues, accumulation and toxicity to various organisms.

Characteristics of Plastic Pollution in the Environment: A Review.

Air Pollution

Environmental and Health Impacts of Air Pollution: A Review.

A time-to-event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta-analysis of 84 cohort studies.

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders.

Association between PM2.5 and risk of hospitalization for myocardial infarction: a systematic review and a meta-analysis.

Miscellaneous

A Systematic Literature Review of Factors Affecting the Timing of Menarche: The Potential for Climate Change to Impact Women’s Health.

New trends in the electrochemical detection of endocrine disruptors in complex media.

Human Health Studies

BPA/Phenols

Rationale and design of a randomized controlled trial examining oral administration of bisphenol A on hepatic glucose production and skeletal muscle insulin sensitivity in adults.

Association of exposure to prenatal phthalate esters and bisphenol A and polymorphisms in the ESR1 gene with the second to fourth digit ratio in school-aged children: data from the Hokkaido Study.

Prenatal urinary concentrations of environmental phenols and birth outcomes in the mother-infant pairs of Tehran Environment and Neurodevelopmental Disorders (TEND) cohort study.

The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients. [BPA and phthalates]

Phthalates

Exposure to Mono-n-Butyl Phthalate in Women with Endometriosis and Its Association with the Biological Effects on Human Granulosa Cells.

Maternal phthalate exposure and asthma, rhinitis and eczema in 552 children aged 5 years; a prospective cohort study.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Can Habitual Exercise Help Reduce Serum Concentrations of Lipophilic Chemical Mixtures? Association between Physical Activity and Persistent Organic Pollutants.

Obesogenic Toxicants in Breast Milk of Lactating Women: Investigation of a Risk Factor for Childhood Obesity.

Association between exposure to persistent organic pollutants and mercury, and glucose metabolism in two Canadian Indigenous populations.

Perfluoroalkyl Substances

Associations between perfluoroalkyl substances and serum lipids in a Swedish adult population with contaminated drinking water.

Intrauterine exposure to perfluorinated compounds and overweight at age 4: A case-control study.

Pesticides

Residential proximity to intensive animal agriculture and risk of lymphohematopoietic cancers in the Agricultural Health Study.

Potentially Toxic Elements

Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children.

Female Infertility Associated with Blood Lead and Cadmium Levels.

Long-term metal exposure changes gut microbiota of residents surrounding a mining and smelting area.

In Utero Exposure to Aluminium and Other Neurotoxic Elements in Urban Coastal South African Women at Delivery: An Emerging Concern.

Associations of exposure to metals with the risk of hypertension among an older population aged 40-75 years in rural southwest China.

Postnatal exposure to mercury and neuropsychological development among preschooler children.

Environmental complex exposure and the risk of influenza-like illness among housewives: A case study in Shanxi Province, China. [PAHs and metals]

Biological Monitoring of Occupational Exposure to Metals in Electric Steel Foundry Workers and Its Contribution to 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine Levels.

Air Pollution

Effects of Particulate Respirator Use on Cardiopulmonary Function in Elderly Women: a Quasi-Experimental Study.

Maternal Exposure to Ambient Air Pollution and Risk of Preeclampsia: A Population-Based Cohort Study in Scania, Sweden.

Is long-term PM1 exposure associated with blood lipids and dyslipidemias in a Chinese rural population?

Stroke burden and mortality attributable to ambient fine particulate matter pollution in 195 countries and territories and trend analysis from 1990 to 2017.

Impact of urban environmental exposures on cognitive performance and brain structure of healthy individuals at risk for Alzheimer’s dementia.

Smoking, air pollution, and lung cancer risk in the Nurses’ Health Study cohort: time-dependent confounding and effect modification.

Ambient temperature and air pollution, and the risk of preterm birth in Tehran, Iran: a time series study.

Effects of Particulate Air Pollution on Tuberculosis Development Methodological Consideration of Long-term Exposure and Time Lag.

Air pollution and hippocampal atrophy in first episode schizophrenia.

Cumulative Lifetime Burden of Cardiovascular Disease From Early Exposure to Air Pollution.

Beyond Smoking: Environmental Determinants of Asthma Prevalence in Western Nepal.

Protocol for a prospective multicenter cross-sectional observational study to investigate the role of air pollution on allergic rhinitis prevalence.

Long-Term Exposure to Air Pollution and Risk of Non-Hodgkin lymphoma in Denmark: A Population-based Case-Control Study.

Miscellaneous

Association between the pregnancy exposome and fetal growth. [numerous chemicals]

Semen endocannabinoids are correlated to sperm quality in a cohort of 200 young Swiss men.

Laboratory Studies

BPA/Phenols

Bisphenol S Impaired Human Granulosa Cell Steroidogenesis in Vitro.

Depot-specific analysis of human adipose cells and their responses to Bisphenol S.

The effects of maternal exposure to BPA during pregnancy on the male reproductive system and the testicular microRNA expression profile.

Bisphenol A affects ovarian development in adolescent mice caused by genes expression change.

Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A in rats.

Bisphenol A enhances adipogenic signaling pathways in human mesenchymal stem cells.

Naringin protects against Bisphenol-A induced oculopathy as implication of cataract in hypertensive rat model.

Phthalates

Investigation of the potential environmental risks of phthalate derivatives designed to be environmentally friendly.

Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the mouse.

Parabens/Triclosan/Antimicrobials/PCPs

Ethylparaben induces apoptotic cell death in human placenta BeWo cells via the Caspase-3 pathway.

Paraben concentrations found in human body fluids do not exert steroidogenic effects in human granulosa primary cell cultures.

Sublethal concentrations of triclosan elicited oxidative stress, DNA damage, and histological alterations in the liver and brain of adult zebrafish.

Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish.

Persistent Organic Pollutants: PCBs, Dioxins/Furans, OCPs

Effects of endocrine disruptor furan on reproductive physiology of Sprague Dawley rats: An F1 Extended One-Generation Reproductive Toxicity Study (EOGRTS).

Perfluoroalkyl Substances

Amphibian Sublethal Exposure to Perfluoroalkyl Substances.

Gender differences in pharmacokinetics of perfluoropentanoic acid using non-linear mixed-effect modeling in rats.

Cytotoxicity of perfluorodecanoic acid on mouse primary nephrocytes through oxidative stress: Combined analysis at cellular and molecular levels.

Interaction between hypoxia and perfluorobutane sulfonate on developmental toxicity and endocrine disruption in marine medaka embryos.

Organotins

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity.

Thyroid disruption and developmental toxicity caused by triphenyltin (TPT) in zebrafish embryos/larvae.

Pesticides

Commercial Formulation of Chlorpyrifos Alters Neurological Behaviors and Fertility.

Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure.

Synergic effects of aerobic exercise and eugenol supplement on germ cell development and testicular tissue structure in chlorpyrifos-treated animal model.

Exposure and post-exposure effects of chlorpyrifos on Carassius auratus gills: An ultrastructural and morphofunctional investigation.

Effects of sublethal and realistic concentrations of the commercial herbicide atrazine in Pacu (Piaractus mesopotamicus): Long-term exposure and recovery assays.

Commercial glyphosate-based herbicides effects on springtails (Collembola) differ from those of their respective active ingredients and vary with soil organic matter content.

Chronic exposure of zebrafish (Danio rerio) to flutolanil leads to endocrine disruption and reproductive disorders.

Reprotoxic effects of the systemic insecticide fipronil on the butterfly Pieris brassicae

The Toxic Effects of Sulfoxaflor Induced in Earthworms (Eisenia fetida) under Effective Concentrations.

Proteomics analysis of zebrafish larvae exposed to 3,4-dichloroaniline using the fish embryo acute toxicity test.

Immunosuppression response to the neonicotinoid insecticide thiacloprid in females and males of the red mason bee Osmia bicornis L.

Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part I: Feminization effects on male rat offspring.

Potentially Toxic Elements

Arsenic Stimulates Myoblast Mitochondrial EGFR to Impair Myogenesis.

Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats.

Differences in toxicity, mitochondrial function and miRNome in human cells exposed in vitro to Cd as CdS quantum dots or ionic Cd.

Long-term cadmium exposure affects cell adhesion and expression of cadherin in the male genital organ of Pardosa pseudoannulata (Bösenberg & Strand, 1906).

Chronic exposure to lead and cadmium pollution results in genomic instability in a model biomonitor species (Apodemus flavicollis Melchior, 1834).

Analysis of vitellogenin by histochemical method as an indicator of estrogenic effect in male Danio rerio exposed to metals.

Heavy metal toxicity has an immunomodulatory effect on metallothionein and glutathione peroxidase gene expression in Cyprinus carpio inhabiting a wetland lake and a culture pond.

Subchronic oral mercury caused intestinal injury and changed gut microbiota in mice.

Chronic arsenate exposure affects amphipod size distribution and reproduction.

Microplastics

Exposure to a microplastic mixture is altering the life traits and is causing deformities in the non-biting midge Chironomus riparius Meigen (1804).

An environmental concentration of aged microplastics with adsorbed silver significantly affects aquatic organisms.

Neurotoxicity, oxidative stress biomarkers and haematological responses in African catfish (Clarias gariepinus) exposed to polyvinyl chloride microparticles.

Air Pollution

Combined exposure of fine particulate matter and high-fat diet aggravate the cardiac fibrosis in C57BL/6J mice.

PM2.5 exposure perturbs lung microbiome and its metabolic profile in mice.

Pharmaceuticals

No evidence that vitellogenin protein expression is induced in marine mussels after exposure to an estrogenic chemical.

Mixtures

Physiological and Transcriptional Effects of Mixtures of Environmental Estrogens, Androgens, Progestins, and Glucocorticoids in Zebrafish.

Interactive effects of mercury exposure and hypoxia on ECG patterns in two Neotropical freshwater fish species: Matrinxã, Brycon amazonicus and traíra, Hoplias malabaricus.

Miscellaneous

Prepubertal acrylamide exposure causes dose-response decreases in spermatic production and functionality with modulation of genes involved in the spermatogenesis in rats.

Non-intentionally added substances (NIAS) in recycled plastics.

Benzo[a]pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling.

Gasoline-derived methyl tert-butyl ether as a potential obesogen linked to metabolic syndrome.

Exposure/Environment Studies

BPA/Phenols

Bisphenol A and its analogs in muscle and liver of fish from the North East Atlantic Ocean in relation to microplastic contamination. Exposure and risk to human consumers.

Occurrence, trophic transfer, and health risk assessment of bisphenol analogues in seafood from the Persian Gulf.

The occurrence and distribution of nonylphenols and nonylphenol ethoxylates in different species of fish.

Phthalates

Occurrence of phthalic acid esters in marine organisms from Hangzhou Bay, China: Implications for human exposure.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Occurrence of organochlorine pesticide residues in biological and environmental matrices in Africa: A two-decade review.

Non-target and target screening of organohalogen compounds in mussels and sediments from Hiroshima Bay, Japan: Occurrence of novel bioaccumulative substances.

Concentrations, toxic equivalence, and age-corrected trends of legacy organic contaminants in Lake Champlain lake trout: 2012-2018.

Temporal trends of legacy organochlorines in different white-tailed eagle (Haliaeetus albicilla) subpopulations: A retrospective investigation using archived feathers.

Incidence of persistent contaminants through blue mussels biomonitoring from Flekkefjord fjord and their relevance to food safety.

Perfluoroalkyl Substances

Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere.

Occurrence, partition and environmental risk assessment of per- and polyfluoroalkyl substances in water and sediment from the Baiyangdian Lake, China.

Perfluoroalkyl substances (PFAS) in tern eggs from St. Brandon’s Atoll, Indian Ocean.

Metals and PFAS in stormwater and surface runoff in a semi-arid Canadian city subject to large variations in temperature among seasons.

Flame Retardants

Distribution behaviour in body compartments and in ovo transfer of flame retardants in North American Great Lakes herring gulls.

Methylsiloxanes and their Brominated Products in one E-waste Recycling Area in China: Emission, Environmental Distribution, and Elimination.

First report on polybrominated diphenyl ethers in the Iranian Coral Islands: Concentrations, profiles, source apportionment, and ecological risk assessment.

Monitoring the levels of brominated and organophosphate flame retardants in passenger cars: Utilisation of car air filters as active samplers.

Pesticides

Occurrences of 29 pesticides in the Huangpu River, China: Highest ecological risk identified in Shanghai metropolitan area.

Potentially Toxic Elements

Potential health risk assessment of toxic metals contamination in clay eaten as pica (geophagia) among pregnant women of Ho in the Volta Region of Ghana.

Factors Associated with High Mercury Levels in Women and Girls from The Mojana Region, Colombia, 2013-2015.

Lead toxicity on a sentinel species subpopulation inhabiting mangroves with different status conservation.

Effects of environmental metal pollution on reproduction of a free-living resident songbird, the tree sparrow (Passer montanus).

Tin and mercury and their speciation (organotin compounds and methylmercury) in worldwide red wine samples determined by ICP-MS and GC-ICP-MS.

Assessment of long-term effects from cage culture practices on heavy metal accumulation in sediment and fish.

Investigation on mercury migration discipline in different paper-plastic food packaging containers.

Microplastics

Weathering and persistence of plastic in the marine environment: Lessons from LEGO.

The removal of microplastics in the wastewater treatment process and their potential impact on anaerobic digestion due to pollutants association. [review]

The Impact of Microplastic Particles on Population Dynamics of Predator and Prey: Implication of the Lotka-Volterra Model.

Pharmaceuticals

Pharmaceuticals and personal care products in a drinking water resource of Yangtze River Delta Ecology and Greenery Integration Development Demonstration Zone in China: Occurrence and human health risk assessment.

Miscellaneous

Building Interdisciplinary Partnerships for Community-Engaged Environmental Health Research in Appalachian Virginia.

Determination of 117 endocrine disruptors (EDCs) in water using SBSE TD-GC-MS/MS under the European Water Framework Directive.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sarah@healthandenvironment.org and ask to join the group EDC_research@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.