A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed over the past two weeks.
Contents: Regulations/ Policy, Methods/Tools/Screening, Commentaries, Reviews/Meta-Analyses, Human Health Studies, Laboratory Studies, Exposure/Environment Studies
Highlights:
- Product selection strategies in shifting chemical exposures among Black women and Latinas
- High-Throughput Suspect Screening Reveals Widespread Pesticide Exposure in Early Childhood
- First study on the toxicokinetic approach of MNPs in an environmentally exposed human population
- Journal of the Endocrine Society Focused Collection: Endocrine-disrupting Chemicals: Environmental Health, Endocrinology, and Beyond
Regulations/Policy
Methods/Tools/Screening
TOXTRUST: a tool leveraging the Dempster-Shafer Theory for robust integration of NAM results in decision-making considering uncertainty.
Commentaries
Carcinogenicity of butyl benzyl phthalate, dibutyl phthalate, and diisononyl phthalate. [News item in The Lancet Oncology]
Reviews/Meta-Analyses
Numerous Chemicals/Mixtures
Bisphenols/Phthalates
Per- and Polyfluoroalkyl Substances Exposure and Ischemic Heart Disease: Emerging Evidence from the Literature Risk Assessment of PFAS-Induced Male Reproductive Toxicity: A Comprehensive Evaluation Using the TRAEC Strategy
PFAS
Per- and Polyfluoroalkyl Substances Exposure and Ischemic Heart Disease: Emerging Evidence from the Literature
Microplastics/Nanomaterials
Air Pollution
Pharmaceuticals/Personal Care Products
Miscellaneous
Human Health Studies
Numerous Chemicals/Mixtures
Bisphenols/Phthalates Lead exposure and risk of ADHD and conduct disorders in children: evidence from a retrospective cohort in Philadelphia, PA
Persistent Organic Pollutants: PCBs, Dioxin, OCPs
PFAS
Associations of maternal PFAS exposure with offspring growth trajectories from birth to age 2 years.
Flame Retardants
Bridging exposure and disease: serum hormones as potential mediators between PBDEs and preeclampsia.
Pesticides
Deltamethrin Placental Transfer and Seasonal Pyrethroid Exposure: A Mother-Newborn Dyad Pilot Study.
Metals/Metalloids
Air Pollution
Miscellaneous
Numerous Chemicals/Mixtures
Investigating the potential mechanism of bisphenols on neurodegeneration through network toxicology and molecular docking.
Perfluorooctanoic Acid (PFOA) Alters the Structure of the Gut Microbial Community and Colonoid Transcription Gestational Arsenic Exposure Induces Metabolic Dysfunction-Associated Fatty Liver Disease-like Phenotypes in Middle-Aged Offspring
Chronic exposure to Bisphenol AF from gestation through adulthood induces renal injury in 8-month-old mice via lipid metabolism dysregulation and ferroptosis.
Integrative Network Toxicology Reveals Potential Molecular Targets Linking Plasticizer Exposure to Inflammatory Gastrointestinal Disorders
Phthalates
Metabolite-driven remodeling of hepatic lipid metabolism by the plasticizer di-isononyl phthalate.
Exploring Toxicological Mechanisms of Typical PFAS-Induced NAFLD through Integrated Computational Toxicology and AOP Frameworks
Parabens/Triclosan/ Antimicrobials
Persistent Organic Pollutants: PCBs, Dioxin, OCPs
PFAS
Perfluorooctane Sulfonate Exposure and Peripheral Artery Disease: Mendelian Randomization and Integrative Multi-Omics Systems Toxicology With Machine Learning.
Transgenerational Effect of a Mixture of Pyrethroids in the Testis of Rats: A Transcriptome and Epigenome Analyses
Flame Retardants
Organotins
Pesticides
Neurotoxicity and Mechanisms of Deltamethrin and Its Metabolite 3-PBA in HT22 Cells.
Metals/Metalloids
Microplastics/Nanomaterials
Transcriptomic responses to repeated exposure of human C3A liver spheroids to polystyrene nanoplastics.
Gut-Microbial Responses to Acute Polyester Microplastic Exposure in Zebrafish: Dysbiosis, Opportunistic Bacteria, and Functional Impact
Oral Administration of Polyethylene Microplastics Induces BPA-Associated Antioxidant Activation and Synaptic-Related Transcriptional Responses in the Rat Prefrontal Cortex 6PPD-quinone exposure and Alzheimer’s disease: insights from integrative network pharmacology, transcriptomics, machine learning, and molecular docking High-Throughput Suspect Screening Reveals Widespread Pesticide Exposure in Early Childhood If you enjoy this newsletter, please feel free to donate here! Thank you!
Air Pollution
Tire Wear Particles
Miscellaneous
Exposure/Environment Studies
Numerous Chemicals/Mixtures
Phthalates
Persistent Organic Pollutants: PCBs, Dioxin, OCPs
PFAS
Flame Retardants
Pesticides
Metals/Metalloids
Microplastics/Nanomaterials
Air Pollution
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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Industry-funded articles are included without notation. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me and ask to join the EDC Science Weekly group EDC_research@ googlegroups.com. There are searchable archives. Compiled by Sarah Howard of Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.
