New EDC articles, Dec 5 – 11, 2018

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week. 

Contents: Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.

Regulations/Policy

Assessing the population relevance of endocrine disrupting effects for non-target vertebrates exposed to plant protection products.

EPA’s non-targeted analysis collaborative trial (ENTACT): genesis, design, and initial findings.

A big data approach with artificial neural network and molecular similarity for chemical data mining and endocrine disruption prediction.

The Journal of Public Health Management and Practice has a 25th anniversary issue on Environmental Health, with a featured supplement on Lead Poisoning Prevention that includes these articles, among many others:

Lead Poisoning Prevention: The Unfinished Agenda.

CDC’s Lead Poisoning Prevention Program: A Long-standing Responsibility and Commitment to Protect Children From Lead Exposure.

Findings of a Statewide Environmental Lead Inspection Program Targeting Homes of Children With Blood Lead Levels as Low as 5 μg/dL.

The Flint Water Crisis: A Coordinated Public Health Emergency Response and Recovery Initiative.

Response to the US FDA LeadCare Testing Systems Recall and CDC Health Alert.

Reviews

Environmentally-related contaminants of high concern: Potential sources and analytical modalities for detection, quantification, and treatment.

Particulate Matter Air Pollution: Effects on the Cardiovascular System.

State of the science review of the health effects of inorganic arsenic: Perspectives for future research.

Chronic mercury exposure and blood pressure in children and adolescents: a systematic review.

Human Health Studies

BPA/Phenols/Phthalates/Parabens

Exposure of environmental Bisphenol A in relation to routine sperm parameters and sperm movement characteristics among fertile men.

Association of phthalates, parabens and phenols found in personal care products with pubertal timing in girls and boys.

Prenatal exposure to phthalates and autism spectrum disorder in the MARBLES study.

Blood pressure changes during pregnancy in relation to urinary paraben, triclosan and benzophenone concentrations: A repeated measures study.

Persistent Organic Pollutants

Association of colorectal polyps and cancer with low-dose persistent organic pollutants: A case-control study.

Serum organochlorine pesticides residues and risk of cancer: A case-control study.

Association of the human aryl hydrocarbon receptor repressor (AhRR)-c.565C>G transversion with male infertility: A case-control study from Iran.

Perfluoroalkyl Substances

Synergistic impact of co-exposures to toxic metals cadmium, lead, and mercury along with perfluoroalkyl substances on the healthy kidney function. [incl metals]

Associations of serum perfluoroalkyl substance and vitamin D biomarker concentrations in NHANES, 2003-2010.

Flame Retardants

Childhood polybrominated diphenyl ether (PBDE) serum concentration and reading ability at ages 5 and 8 years: The HOME Study.

Arsenic/Metals

Prenatal metal concentrations and childhood cardio-metabolic risk using Bayesian Kernel Machine Regression to assess mixture and interaction effects.

Associations between Water Quality Measures and Chronic Kidney Disease Prevalence in Taiwan.

Urinary metabolomics reveals novel interactions between metal exposure and amino acid metabolic stress during pregnancy.

The role of gut microbiome and its interaction with arsenic exposure in carotid intima-media thickness in a Bangladesh population.

Arsenic Exposure and Incident Hypertension of Adult Residents Living in Rural Areas Along the Yangtze River, Anhui, China.

Lead exposure during childhood and subsequent anthropometry through adolescence in girls.

Pharmaceuticals

Prenatal Progestin Exposure Is Associated With Autism Spectrum Disorders.

Laboratory Studies

BPA/Phenols

In vitro antioxidant efficacy and the therapeutic potential of Wendlandia heynei (Schult.) Santapau: Merchant against bisphenol A-induced hepatotoxicity in rats.

17α-Ethynylestradiol and 4-nonylphenol stimulate lung adenocarcinoma cell production in xenoestrogenic way.

Bisphenol F causes disruption of gonadotropin-releasing hormone neural development in zebrafish via an estrogenic mechanism.
Cardiovascular effects and molecular mechanisms of bisphenol A and its metabolite MBP in zebrafish.

Food up-take and reproduction performance of Daphnia magna under the exposure of Bisphenols.

Octylphenol influence growth and development of Rana chensinensis tadpoles via disrupting thyroid function.

Phthalates

Analysis of Lipid Metabolism, Immune Function, and Neurobehavior in Adult C57BL/6JxFVB Mice After Developmental Exposure to di (2-ethylhexyl) Phthalate.

Persistent Organic Pollutants

Exposure to 2,3,7,8-tetrachlorodibenzo-paradioxin (TCDD) hampers the host defense capability of a bivalve species, Tegillarca granosa.

Human AHR functions in vascular tissue: Pro- and anti-inflammatory responses of AHR agonists in atherosclerosis.

Perfluoroalkyl Substances

Perfluorinated compounds binding to estrogen receptor of different species: a molecular dynamic modeling.

Biphasic effects of perfluorooctanoic acid on steroidogenesis in mouse Leydig tumour cells.

Developmental Perfluorooctane Sulfonate Exposure Inhibits Long-term Potentiation by Affecting AMPA Receptor Trafficking.

Perfluorononanoic acid (PFNA) alters lipid accumulation in bovine blastocysts after oocyte exposure during in vitro maturation.

Arsenic/Metals

Arsenite renal apoptotic effects in chickens co-aggravated by oxidative stress and inflammatory response.

Methyl-mercury induces apoptosis through ROS-mediated endoplasmic reticulum stress and mitochondrial apoptosis pathways activation in rat cortical neurons.

Arsenic aggravated reproductive toxicity in male rats exposed to lead during the perinatal period.

Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis.

Cadmium-induced neurodegeneration and activation of noncanonical sonic hedgehog pathway in rat cerebellum.

Marginal Zinc Deficiency and Environmentally Relevant Concentrations of Arsenic Elicit Combined Effects on the Gut Microbiome.

Pigeon odor varies with experimental exposure to trace metal pollution.

Exposure to mixtures of mercury, cadmium, lead, and arsenic alters the disposition of single metals in tissues of Wistar rats.

Ellagic and ferulic acids protect arsenic-induced male reproductive toxicity via regulating Nfe2l2, Ppargc1a and StAR expressions in testis.

Organotins

RIP1 and RIP3 contribute to Tributyltin-induced toxicity in vitro and in vivo.

Expression of mGlu Receptor Genes in the Hippocampus After Intoxication with Trimethyltin.

Miscellaneous

Estrogenic activity of multicyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss) in vitro assays.

Phytol ameliorated benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice via inhibition of oxidative stress and apoptosis.

Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes.

Genotoxic effects of combined multiple stressors on Gammarus locusta haemocytes: Interactions between temperature, pCO2 and the synthetic progestin levonorgestrel.

Wildlife/Environment/Exposure Studies

Phthalates

Detection and quantification analysis of chemical migrants in plastic food contact products. [phthalates, phenols, etc.] 

Occurrence and distribution of phthalate esters in freshwater aquaculture fish ponds in Pearl River Delta, China.

Parabens/Triclosan/Antimicrobials

Exposure to selected preservatives in personal care products: case study comparison of exposure models and observational biomonitoring data. [parabens]

Tissue-specific Accumulation and Body Burden of Parabens and Their Metabolites in Small Cetaceans.

Persistent Organic Pollutants

Persistent organic pollutants in sediments, intertidal crabs, and the threatened Olrog’s gull in a northern Patagonia salt marsh, Argentina.

Passive sampling of pesticides and polychlorinated biphenyls (PCBs) along the Quequén Grande River watershed (Argentina).

Legacy and Emerging Persistent Organic Pollutants (POPs) in Terrestrial Compartments in the High Arctic: Sorption and Secondary Sources.

Persistent organic pollutants (POPs) in edible fish species from different fishing zones of Croatian Adriatic.

Accumulation of organochlorine pesticides in reef organisms from marginal coral reefs in South Africa and links with coastal groundwater.

Organochlorine pesticides and polychlorinated biphenyls in the Bering flounder (Hippoglossoides robustus) from the Sea of Okhotsk.

Persistent Organic Pollutants in two species of migratory birds from Rothera Point, Adelaide Island, Antarctica.

Perfluoroalkyl Substances

Poly- and Perfluoroalkyl Substances in Runoff Water and Wastewater Sampled at a Firefighter Training Area.

Oxidative conversion of potential perfluoroalkyl acid precursors in Jiaozhou Bay and nearby rivers and sewage treatment plant effluent in China.

Accumulation of perfluorinated alkyl substances (PFAS) in agricultural plants: A review.

Perfluoroalkyl acids in drinking water of China in 2017: Distribution characteristics, influencing factors and potential risks.

Does soil track-in contribute to house dust concentrations of perfluoroalkyl acids (PFAAs) in areas affected by soil or water contamination?

Flame Retardants

Release and Transformation of BTBPE During the Thermal Treatment of Flame Retardant ABS Plastics.

Legacy and alternative flame retardants in house dust and hand wipes from South China.

Arsenic/Metals

Migration of lead and arsenic from food contact paper into a food simulant and assessment of their consumer exposure safety.

Surface sediment properties and heavy metal contamination assessment in river sediments of the Pearl River Delta, China.

Bioaccumulation of mercury and other trace elements in bottom-dwelling omnivorous fishes: The case of Diplodus sargus (L.) (Osteichthyes: Sparidae).

Evaluation of heavy metals and environmental risk assessment in the Mangrove Forest of Kuala Selangor estuary, Malaysia.

The effect of contemporary mine emissions on children’s blood lead levels.

Impact of eutrophication on arsenic cycling in freshwaters.
The impact of dam flushing event on dissolved trace elements concentrations: Coupling integrative passive sampling and discrete monitoring.

Arsenic concentrations, speciation, and localization in 141 cultivated market mushrooms: implications for arsenic exposure to humans.

Ecological risk assessment of heavy metals in surface sediments from the Gorgan Bay, Caspian Sea.

The sources and ecological risk assessment of elemental pollution in sediment of Linggi estuary, Malaysia.

Spatial and seasonal characteristics of dissolved heavy metals in the surface seawater of the Yellow River Estuary, China.

Human health risk assessment for some toxic metals in widely consumed rice brands (domestic and imported) in Tehran, Iran: Uncertainty and sensitivity analysis.

Miscellaneous

Impact of Soil Filtration on Metals, Nutrients, and Estrogenic Activity of Reclaimed Water.

Examining the role of estrogenic activity and ocean temperature on declines of a coastal demersal flatfish population near the municipal wastewater outfall of Orange County, California, USA.

Occurrence and levels of micropollutants across environmental and engineered compartments in Austria PAHs, PBDEs, organotins, PFASs, and metals

Pyr-GC/MS analysis of microplastics extracted from the stomach content of benthivore fish from the Texas Gulf Coast.

Polycyclic and organochlorine hydrocarbons in sediments of the northern South China Sea.

This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed.  Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.