A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.
Contents: Interesting Research of the Week, Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.
Interesting Research of the Week
New approaches to cope with possible harms of low-dose environmental chemicals.
Regulations/Policy
Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution.
A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing.
Guideline levels for PFOA and PFOS in drinking water: the role of scientific uncertainty, risk assessment decisions, and social factors.
Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge.
Chemical carcinogenicity revisited 3: Risk assessment of carcinogenic potential based on the current state of knowledge of carcinogenesis in humans.
Reviews
Health risks of chemicals in consumer products: A review.
Inhibitor of DNA-Binding/Differentiation Proteins and Environmental Toxicants: Genomic Impact on the Onset of Depressive Dysfunction.
Computational prediction models for assessing endocrine disrupting potential of chemicals.
The Utility of Zebrafish as a Model for Screening Developmental Neurotoxicity.
Effects of 25 thyroid hormone disruptors on zebrafish embryos: A literature review of potential biomarkers.
Food advanced glycation end products as potential endocrine disruptors: An emerging threat to contemporary and future generation.
BPA/Phenols/Phthalates
BPA and nutraceuticals, simultaneous effects on endocrine functions.
Persistent Organic Pollutants
Veterans and Agent Orange: Update 11 (2018).
Perfluorohexanoic acid toxicity, part II: Application of human health toxicity value for risk characterization.
PAHs
Beyond the obvious: Environmental health implications of polar polycyclic aromatic hydrocarbons.
Human Health Studies
BPA/Phenols/Phthalates/Parabens
Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort.
Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men.
Urinary Phthalate Biomarker Concentrations and Postmenopausal Breast Cancer Risk.
Maternal urinary phthalate metabolites in relation to gestational diabetes and glucose intolerance during pregnancy.
Prenatal Exposure to Select Phthalates and Phenols and Associations with Fetal and Placental Weight among Male Births in the EDEN Cohort (France).
Persistent Organic Pollutants
Associations of multiple exposures to persistent toxic substances with the risk of hyperuricemia and subclinical uric acid levels in BIOAMBIENT.ES study.
Perfluoroalkyl Substances
Exposure to Perfluoroalkyl Substances during Fetal Life and Pubertal Development in Boys and Girls from the Danish National Birth Cohort.
Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and the risk of hypertensive disorders of pregnancy.
Perfluoroalkyl substances and risk of type II diabetes: A prospective nested case-control study.
Arsenic/Metals
Exposure to heavy metals during pregnancy related to gestational diabetes mellitus in diabetes-free mothers.
Bayesian Hierarchical Models as Tools to Evaluate the Association Between Groundwater Quality and the Occurrence of Type 2 Diabetes in Rural Saskatchewan, Canada.
Pharmaceuticals
Neurodevelopmental disorders in children exposed in utero to synthetic progestins: analysis from the national cohort of the Hhorages Association.
Laboratory Studies
BPA/Phenols/Phthalates
Differential Hepatic Gene Expression Profile of Male Fathead Minnows Exposed to Daily Varying Dose of Environmental Contaminants Individually and in Mixture.
Response of Pseudomonas fluorescens to dimethyl phthalate.
Parabens/Triclosan/Antimicrobials
Exposure to triclosan changes the expression of microRNA in male juvenile zebrafish (Danio rerio).
Pesticides
Exposure to atrazine during puberty reduces sperm viability, increases weight gain and alters the expression of key metabolic genes in the liver of male mice.
Long-term Immunotoxic effects of oral prenatal and neonatal atrazine exposure.
Compound and Dose-Dependent Effects of Two Neonicotinoid Pesticides on Honey Bee (Apis mellifera) Metabolic Physiology.
Multiple biomarkers based appraisal of deltamethrin induced toxicity in silver carp (Hypophthalmichthys molitrix).
Developmental exposure to environmentally relevant concentrations of bifenthrin alters transcription of mTOR and ryanodine receptor-dependent signaling molecules and impairs predator avoidance behavior across early life stages in inland silversides (Menidia beryllina).
Arsenic/Metals
Transgenerational Effects of Periconception Heavy Metal Administration on Adipose Weight and Glucose Homeostasis in Mice at Maturity.
Serum metabolomics reveals that gut microbiome perturbation mediates metabolic disruption induced by arsenic exposure in mice.
Zinc Deficiency and Arsenic Exposure Can Act Both Independently or Cooperatively to Affect Zinc Status, Oxidative Stress, and Inflammatory Response.
Effects of Developmental Arsenic Exposure on the Social Behavior and Related Gene Expression in C3H Adult Male Mice.
Effects of Chronic Exposure to Mercury on Angiotensin-Converting Enzyme Activity and Oxidative Stress in Normotensive and Hypertensive Rats.
Wildlife/Environment/Exposure Studies
BPA/Phenols
Determination of bisphenol A and bisphenol S concentrations and assessment of estrogen- and anti-androgen-like activities in thermal paper receipts from Brazil, France, and Spain.
Phthalates
Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay.
Spatial distribution and mass loading of phthalate esters in wastewater treatment plants in China: An assessment of human exposure.
[Characteristics of Phthalic Acid Esters Pollution in Urban Surface Runoff in Shanghai, China]. [Chinese]
Persistent Organic Pollutants
Prenatal exposure to persistent organic pollutants in Northern Tanzania and their distribution between breast milk, maternal blood, placenta and cord blood.
Risk characterisation from the presence of environmental contaminants and antibiotic residues in wild and farmed salmon from different FAO zones.
Dioxins levels in human blood after implementation of measures against dioxin exposure in Japan.
Absence of PCB Hot Spot Effect in Walleye Sander vitreus from Lower Green Bay of Lake Michigan.
Persistent Organic Pollutants in Livers and Hg in Feathers of Neotropic Cormorants (Phalacrocorax brasilianus) from the Trinity River Watershed (Texas, USA).
Determination of Occurrences, Distribution, Health Impacts of Organochlorine Pesticides in Soils of Central China.
Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor).
[Characteristics of Organochlorine Pesticides (OCPs) in Soil Samples of Hanjiang River Basin, Southeast China]. [Chinese]
Perfluoroalkyl Substances
Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women.
A transgenerational toxicokinetic model and its use in derivation of Minnesota PFOA water guidance.
Distribution of perfluorinated alkyl substances in marine shellfish along the Chinese Bohai Sea coast.
[Spatial Distribution of Perfluoroalkyl Acids and Transformation of Their Precursors in River Water Samples and Effluents of Wastewater Treatment Plans in a Typical Tourism City]. [Chinese]
[Distribution and Fluxes of Perfluoroalkyl and Polyfluoroalkyl Substances in the Middle Reaches of the Yellow River (Weinan-Zhengzhou Section)]. [Chinese]
Flame Retardants
Concentrations and occupational exposure assessment of polybrominated diphenyl ethers in modern Chinese e-waste dismantling workshops.
Pesticides
Longitudinal, Seasonal, and Occupational Trends of Multiple Pesticides in House Dust.
Occurrence, distribution and ecological risks of antibiotics and pesticides in coastal waters around Liaodong Peninsula, China.
Arsenic/Metals
Hijiki seaweed consumption elevates levels of inorganic arsenic intake in Japanese children and pregnant women.
Evaluation of the status and the relationship between essential and toxic elements in the hair of occupationally exposed workers.
PM2.5-Bound Toxic Elements in an Urban City in East China: Concentrations, Sources, and Health Risks.
Environmentally relevant methylmercury exposure reduces the metabolic scope of a model songbird.
Miscellaneous
First account of plastic pollution impacting freshwater fishes in the Amazon: Ingestion of plastic debris by piranhas and other serrasalmids with diverse feeding habits.
Comparison of Temperate and Tropical Freshwater Species’ Acute Sensitivities to Chemicals: An Update.
Small but with big impact? Ecotoxicological effects of a municipal wastewater effluent on a small creek.
Endocrine-disrupting compounds in the Xiangjiang River of China: Spatio-temporal distribution, source apportionment, and risk assessment.
Influence of anthropogenic activities and risk assessment on protected mangrove forest using traditional and emerging molecular markers (Ceará coast, northeastern Brazil). [PAHs, AHs, pesticides, hormones]
This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.
