A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed over the past 2 weeks.
Contents: Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.
Regulations/Policy
EcoToxChip: A next-generation toxicogenomics tool for chemical prioritization and environmental management.
Statistical Approaches for Investigating Periods of Susceptibility in Children’s Environmental Health Research.
Perspectives on trace chemical safety and chemophobia: risk communication and risk management.
Reviews
History of the Obesogen Field: Looking Back to Look Forward
Interventions to Address Environmental Metabolism-Disrupting Chemicals: Changing the Narrative to Empower Action to Restore Metabolic Health
Identification and Prioritization of Environmental Reproductive Hazards: A First Step in Establishing Environmental Perinatal Care.
Environmental exposures during pregnancy: Mechanistic effects on immunity.
Environmental Chemical Contaminants in Food: Review of a Global Problem.
Occurrence of environmental pollutants in foodstuffs: A review of organic vs. conventional food.
The impact of environmental pollution on the quality of mother’s milk.
Metabolism Disrupting Chemicals and Alteration of Neuroendocrine Circuits Controlling Food Intake and Energy Metabolism.
Endocrine Disrupting Chemicals Interfere With Leydig Cell Hormone Pathways During Testicular Descent in Idiopathic Cryptorchidism.
Comparative Overview of the Mechanisms of Action of Hormones and Endocrine Disruptor Compounds.
Prenatal determinants of childhood obesity: a review of risk factors.
BPA/Phenols/Phthalates
A mini review of bisphenol A (BPA) effects on cancer-related cellular signaling pathways.
Do Prenatal Exposures Pose a Real Threat to Ovarian Function? BPA as a Case Study.
The role of exposure to phthalates in variations of anogenital distance: A systematic review and meta-analysis.
Persistent Organic Pollutants
Mechanisms of Developmental Toxicity of Dioxins and Related Compounds.
Environmental Pollutants Effect on Brown Adipose Tissue. [DDT/DDE, PFASs, air pollution]
Associations between exposure to organochlorine chemicals and endometriosis in experimental studies: A systematic review protocol.
Metals
Bi-directional regulation of TGF-β/Smad pathway by arsenic: A systemic review and meta-analysis of in vivo and in vitro studies.
A Review of Metal Exposure and Its Effects on Bone Health.
Systemic sclerosis and exposure to heavy metals.
Metal Toxicity Links to Alzheimer’s Disease and Neuroinflammation.
Nanoparticles
Innate Immunity Provides Biomarkers of Health for Teleosts Exposed to Nanoparticles.
Human Health Studies
BPA/Phenols
First trimester maternal exposures to endocrine disrupting chemicals and metals and fetal size in the Michigan Mother-Infant Pairs study. [phenols, phthalates, metals, arsenic]
Phthalates
Pregnancy phthalate metabolite concentrations and infant birth weight by gradations of maternal glucose tolerance.
Associations of phthalate exposure with lipid levels and insulin sensitivity index in children: A prospective cohort study.
Disease burden attributable to endocrine-disrupting chemicals exposure in China: A case study of phthalates.
The relationships between urinary phthalate metabolites, reproductive hormones and semen parameters in men attending in vitro fertilization clinic.
Parabens/Triclosan/Antimicrobials
Correlates of exposure to phenols, parabens, and triclocarban in the Study of Environment, Lifestyle and Fibroids.
Persistent Organic Pollutants
Association between prenatal exposure to multiple persistent organic pollutants (POPs) and growth indicators in newborns.
Early-life exposure to persistent organic pollutants (OCPs, PBDEs, PCBs, PFASs) and attention-deficit/hyperactivity disorder: A multi-pollutant analysis of a Norwegian birth cohort.
Drivers of maternal accumulation of organohalogen pollutants in Arctic areas (Chukotka, Russia) and 4,4′-DDT effects on the newborns.
Prediagnostic serum organochlorine insecticide concentrations and primary liver cancer: a case-control study nested within two prospective cohorts.
Exposure to polybrominated biphenyl (PBB) associates with genome-wide DNA methylation differences in peripheral blood.
Breast Cancer and Exposure to Organochlorines in the CECILE Study: Associations with Plasma Levels Measured at the Time of Diagnosis and Estimated during Adolescence.
Polychlorinated biphenyls influence on autism spectrum disorder risk in the MARBLES cohort.
Prenatal exposure to organohalogen compounds and children’s mental and motor development at 18 and 30 months of age.
Perfluoroalkyl Substances
Prenatal exposure to perfluoroalkyl substances is associated with lower hand, foot and mouth disease viruses antibody response in infancy: Findings from the Guangzhou Birth Cohort Study.
Maternal levels of perfluoroalkyl substances (PFASs) during pregnancy and childhood allergy and asthma related outcomes and infections in the Norwegian Mother and Child (MoBa) cohort.
Associations of Fetal Growth Outcomes with Measures of the Combined Xenoestrogenic Activity of Maternal Serum Perfluorinated Alkyl Acids in Danish Pregnant Women.
Pesticides
Organophosphate Pesticide Metabolite Concentrations in Urine during Pregnancy and Offspring Nonverbal IQ at Age 6 Years.
Pesticide Exposure and Stunting among Children in Agricultural Areas.
Exposure to Pesticides and Health Effects on Farm Owners and Workers From Conventional and Organic Agricultural Farms in Costa Rica: Protocol for a Cross-Sectional Study.
Arsenic/Metals
Low to moderate toenail arsenic levels in young adulthood and incidence of diabetes later in life: findings from the CARDIA Trace Element study.
Effects of seafood consumption and toenail mercury and selenium levels on cognitive function among American adults: 25 y of follow up.
Global burden of cancer and coronary heart disease resulting from dietary exposure to arsenic, 2015.
Association between plasma concentration of copper and gestational diabetes mellitus.
Miscellaneous
Circulating androgens and postmenopausal ovarian cancer risk in the Women’s Health Initiative Observational Study.
Laboratory Studies
BPA/Phenols
Identification of metabolic pathways related to the bisphenol A-induced adipogenesis in differentiated murine adipocytes by using RNA-sequencing.
Evaluation of bisphenol A exposure induced oxidative RNA damage by liquid chromatography-mass spectrometry.
Rapid effect of bisphenol A on glutamate-induced Ca2+ influx in hippocampal neurons of rats.
Ecotoxicity of Caenorhabditis elegans following a step and repeated chronic exposure to tetrabromobisphenol A.
Supraphysiological concentrations of Bisphenol A alter the expression of extracellular vesicle-enriched miRNAs from human primary granulosa cells.
Bisphenol S promotes the cell cycle progression and cell proliferation through ERα-cyclin D-CDK4/6-pRb pathway in MCF-7 breast cancer cells.
Cytotoxic and genotoxic effects of environmental relevant concentrations of bisphenol A and interactions with doxorubicin.
Determination and reduced life expectancy model and molecular docking analyses of estrogenic potentials of 17β-estradiol, bisphenol A and nonylphenol on expression of vitellogenin gene (vtg1) in zebrafish.
Use of a Mouse Model of Experimentally Induced Endometriosis to Evaluate and Compare the Effects of Bisphenol A and Bisphenol AF Exposure.
Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells.
Characterization of Follicular Atresia Responsive to BPA in Zebrafish by Morphometric Analysis of Follicular Stage Progression.
Nonylphenol promotes the proliferation of colorectal cancer COLO205 cells by upregulating the expression of protein kinase C ζ.
Both BPA/Phenols and Phthalates
Selected bisphenols and phthalates screened for estrogen and androgen disruption by in silico and in vitro methods.
Endocrine-disrupting chemicals impair the innate immune prophenoloxidase system in the intertidal mud crab, Macrophthalmus japonicus.
Phthalates
Chronic Low-Dose Nonylphenol or Di-(2-ethylhexyl) Phthalate has a Different Estrogen-like Response in Mouse Uterus.
The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity.
In vitro evaluation of cytotoxic and genotoxic effects of Di(2-ethylhexyl)-phthalate (DEHP) on European sea bass (Dicentrarchus labrax) embryonic cell line.
Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate.
Parabens/Triclosan/Antimicrobials
Toxicities of Four Parabens and Their Mixtures to Daphnia magna and Aliivibrio fischeri.
Persistent Organic Pollutants
Measurement of the agonistic activities of monohydroxylated polychlorinated biphenyls at the retinoid X and retinoic acid receptors using recombinant yeast cells.
Evaluation of the developmental toxicity of 2,7-dibromocarbazole to zebrafish based on transcriptomics assay.
Type 3 innate lymphoid cells are altered in colons of C57BL/6 mice with dioxin exposure.
Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads.
Co-expression of the aryl hydrocarbon receptor and estrogen receptor in the developing teeth of rat offspring after rat mothers’ exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and the protective action of α-tocopherol and acetylsalicylic acid.
Sex-specific alterations of lipid metabolism in zebrafish exposed to polychlorinated biphenyls.
Identification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs).
Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls.
Perfluoroalkyl Substances
The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice.
Neurotoxic effects of perfluoroalkyl acids：neurobehavioral deficit and its molecular mechanism.
Perfluorooctanoic acid exposure induces apoptosis in SMMC-7721 hepatocellular cancer cells.
Perfluorooctanoic acid disrupts gap junction intercellular communication and induces reactive oxygen species formation and apoptosis in mouse ovaries.
Hepatic Carboxylesterases are Differentially Regulated in PPARα-Null Mice Treated with Perfluorooctanoic Acid.
Perfluorooctanoic acid (PFOA) and perfluooctane sulfonate (PFOS) induce different modes of action in reproduction to Japanese medaka (Oryzias latipes).
Pesticides
High temperature aggravates the effects of pesticides in goldfish.
Immunostimulating effects of Ginkgo biloba extract against toxicity induced by organophosphate pesticide, diazinon in rainbow trout, Oncorhynchus mykiss: innate immunity components and immune-related genes.
Agrochemical mixtures and amphibians: The combined effects of pesticides and fertilizer on stress, acetylcholinesterase activity and bioaccumulation in a terrestrial environment.
Genotoxic and immunotoxic effects of the organophosphate metabolite diethyldithiophosphate (DEDTP) in Vivo.
Evaluation on the thyroid disrupting mechanism of malathion in Fischer rat thyroid follicular cell line FRTL-5.
Ioxynil and diethylstilbestrol disrupt vascular and heart development in zebrafish.
Toxicological impact of oxyfluorfen 24% herbicide on the reproductive system, antioxidant enzymes, and endocrine disruption of Biomphalaria alexandrina (Ehrenberg, 1831) snails.
The Effects of Bifenthrin and Temperature on the Endocrinology of Juvenile Chinook Salmon.
Sub-lethal toxicity of chlorpyrifos alone and in combination with polyethylene glycol to common carp (Cyprinus carpio).
Analysis of long non-coding RNA involved in atrazine-induced testicular degeneration of Xenopus laevis.
Chlorothalonil inhibits mouse ovarian development through endocrine disruption.
Arsenic/Metals
Protective effects of a novel pyrazolecarboxamide derivative against lead nitrate induced oxidative stress and DNA damage in Clarias gariepinus.
Essential element Cu and non-essential element Hg exposures have different toxicological effects in the liver of large yellow croaker.
Bacterial diet and weak cadmium stress affect the survivability of Caenorhabditis elegans and its resistance to severe stress.
Exposure to environmentally relevant cadmium concentrations negatively impacts early life stages of channel catfish (Ictalurus punctatus).
Cadmium disrupts melanocortin 2 receptor signaling in rainbow trout.
Evidences for involvement of estrogen receptor induced ERK1/2 activation in ovarian cancer cell proliferation by Cadmium Chloride.
Arsenic induces gender difference of estrogen receptor in AECII cells from ICR fetal mice.
Metabolic Phenotype of Wild-Type and As3mt-Knockout C57BL/6J Mice Exposed to Inorganic Arsenic: The Role of Dietary Fat and Folate Intake.
Taurine protected As2O3-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Effect of arsenic exposure on early eye development in zebrafish (Danio rerio).
Arsenic‑induced BRCA1 CpG promoter methylation is associated with the downregulation of ERα and resistance to tamoxifen in MCF7 breast cancer cells and mouse mammary tumor xenografts.
Organotins
Effects of exposure to triphenyltin (TPT) contaminant on sperm activity in adulthood of Calomys laucha exposed through breastfeeding.
Aging and retinoid X receptor agonists on masculinization of female Pomacea canaliculata, with a critical appraisal of imposex evaluation in the Ampullariidae.
Retraction Note: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.
Cardiotoxicity of environmental contaminant tributyltin involves myocyte oxidative stress and abnormal Ca2+ handling.
Mixtures
Assessment of the toxic effects of mixtures of three lanthanides (Ce, Gd, Lu) to aquatic biota.
Photochemical behavior of benzophenone sunscreens induced by nitrate in aquatic environments.
Oxidative stress in the galaxiid fish, Galaxias maculatus, exposed to binary waterborne mixtures of the pro-oxidant cadmium and the anti-oxidant diclofenac.
Exposure to cadmium and mono-(2-ethylhexyl) phthalate induce biochemical changes in rat liver, spleen, lung and kidney as determined by attenuated total reflection-Fourier transform infrared spectroscopy.
Combined proteomic and miRNome analyses of mouse testis exposed to an endocrine disruptors chemicals mixture reveals altered toxicological pathways involved in male infertility. [phenols and phthalates]
Miscellaneous
Estrogen sensitive liver transgenic zebrafish (Danio rerio) line (Tg(vtg1:mCherry)) suitable for the direct detection of estrogenicity in environmental samples.
Wildlife/Environment/Exposure Studies
BPA/Phenols
Preliminary study on bisphenol A levels and possible exposure history of mother and exclusively breastfed infant pairs.
Estimation of community-wide exposure to bisphenol A via water fingerprinting.
Determination of Bisphenol A in Red Wine using a Double Vortex-Ultrasound Assisted Microextraction Assay: Role of the Interfacial Properties.
Analysis of Environmental Protection Agency priority endocrine disruptor hormones and bisphenol A in tap, surface and wastewater by online concentration liquid chromatography tandem mass spectrometry.
Dietary intake of 4-nonylphenol and bisphenol A in Taiwanese population: Integrated risk assessment based on probabilistic and sensitive approach.
Phthalates
Phthalate exposure and cumulative risk in a Chinese newborn population.
Phthalate exposure in pregnant women and the influence of exposure to environmental tobacco smoke.
Profiling and comparison of toxicant metabolites in hair and urine using a mass spectrometry-based metabolomic data processing method.
The occurrence, composition and partitioning of phthalate esters (PAEs) in the water-suspended particulate matter (SPM) system of Lake Chaohu, China.
Occurrence of legacy and alternative plasticizers in indoor dust from various EU countries and implications for human exposure via dust ingestion and dermal absorption.
Comprehensive review of 2-ethyl-1-hexanol as an indoor air pollutant.
Parabens/Triclosan/Antimicrobials
Relationship between personal care products usage and triclosan exposure: the second Korean National Environmental Health Survey (KoNEHS 2012-2014).
Persistent Organic Pollutants
Occurrence, seasonal variety of organochlorine compounds in street dust of Novi Sad, Serbia, and its implication for risk assessment.
PCDDs, PCDFs and PCBs in locally produced foods as health risk factors in Silesia Province, Poland.
Climate Influence on Legacy Organochlorine Pollutants in Arctic Seabirds.
Bioaccumulation of organochlorine compounds in large, threatened elasmobranchs off northern New South Wales, Australia.
PCDD/F and PCB levels in different tissues from dugongs (Dugong dugon) inhabiting the Queensland coastline.
Organic pollutants in marine plastic debris from Canary Islands beaches.
Recent history of persistent organic pollutants (PAHs, PCBs, PBDEs) in sediments from a large tropical lake.
Characterizing PCB Exposure Pathways from Sediment and Water in Aquatic Life Using a Food Web Bioaccumulation Model.
Characteristics of PCDD/Fs in soil and sediment samples collected from A-So former airbase in Central Vietnam.
Halogenated organic pollutants in sediments and organisms from mangrove wetlands of the Jiulong River Estuary, South China.
Perfluoroalkyl Substances
Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies.
Decreased plasma levels of perfluoroalkylated substances one year after bariatric surgery.
Hand wipes: a useful tool for assessing human exposure to poly- and perfluoroalkyl substances (PFASs) through hand-to-mouth and dermal contacts.
Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, South Carolina, United States: Exposure and risk assessment.
Per- and polyfluoroalkyl substances (PFASs) in precipitation from mainland China: Contributions of unknown precursors and short-chain (C2C3) perfluoroalkyl carboxylic acids.
Per- and polyfluoroalkyl substances in two different populations of northern cardinals.
Minimal risk of PFOS residues in eel to Māori consumers.
Perfluorinated Alkyl Acids in Hawaiian Cetaceans and Potential Biomarkers of Effect: Peroxisome Proliferator-Activated Receptor Alpha and Cytochrome P450 4A.
Bioaccumulation behavior and spatiotemporal trends of per- and polyfluoroalkyl substances in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
Flame Retardants
Hydrophobic Organic Pollutants in Soils and Dusts at Electronic Waste Recycling Sites: Occurrence and Possible Impacts of Polybrominated Diphenyl Ethers.
Growth and antioxidative response of two mangrove plants to interaction between aquaculture effluent and BDE-99.
Polybrominated diphenyl ethers (PBDEs) in soil and dust from plastic production and surrounding areas in eastern of China.
Occurrence, levels and profiles of brominated flame retardants in daily-use consumer products on the Chinese market.
Spatial and Temporal Trends (2004 – 2016) of Selected Alternative Flame Retardants in Fish of the Laurentian Great Lakes.
Reflection of concentrations of polybrominated diphenyl ethers in health risk assessment: A case study in sediments from the metropolitan river, North China.
Levels of polybrominated diphenyl ethers and hexabromocyclododecane in treatment plant sludge: Implications on sludge management.
Pesticides
Endocrine disrupting pesticides in soil and their health risk through ingestion of vegetables grown in Pakistan.
Arsenic/Metals
Recent advances in arsenic metabolism in plants: current status, challenges and highlighted biotechnological intervention to reduce grain arsenic in rice.
Changes in arsenic exposure in Araihazar, Bangladesh from 2001 through 2015 following a blanket well testing and education campaign.
Targeting at risk households in Bangladesh exposed to arsenic contamination: a spatial analysis.
Gene-environment interaction and maternal arsenic methylation efficiency during pregnancy.
Assessment of 22 inorganic elements in human amniotic fluid: a cross-sectional study conducted in Canary Islands (Spain).
Relationship between arsenic accumulation in tissues and hematological parameters in mullet caught in Faro Lake: a preliminary study.
Arsenic Distribution Assessment in a Residential Area Polluted with Mining Residues.
Quantitative evaluation of heavy metals’ pollution hazards and estimation of heavy metals’ environmental costs in leachate during food waste composting.
Trophic transfer of cadmium in marine food webs from Western Chilean Patagonia and Antarctica.
Arsenic, selenium, and metals in a commercial and vulnerable fish from southwestern Atlantic estuaries: distribution in water and tissues and public health risk assessment.
Arsenic contamination of rural community wells in Nicaragua: A review of two decades of experience.
Arsenic, antimony, and nickel leaching from northern peatlands treating mining influenced water in cold climate.
Health risk assessment of arsenic and other potentially toxic elements in drinking water from an industrial zone of Gujrat, Pakistan: a case study.
The fate of selected heavy metals and arsenic in a constructed wetland.
Organotins
Assessment of the organotin pollution in the coastal sediments of the Western Arabian Gulf, Saudi Arabia.
Miscellaneous
Environmental contaminants in fish species from a large dam reservoir and their potential risks to human health. [metals, OCPs, antibiotics]
Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River. (pharmaceuticals, pesticides, steroids and PFASs)
Transformation of endocrine disrupting chemicals, pharmaceutical and personal care products during drinking water disinfection.
Occurrence, toxicity and transformation of six typical benzotriazoles in the environment: A review.
This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal
