A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.
Contents: Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.
Reviews
Immunomodulatory effects of synthetic endocrine disrupting chemicals on the development and functions of human immune cells.
Environmental ototoxicants, a potential new class of chemical stressors.
Statistical Methodology in Studies of Prenatal Exposure to Mixtures of Endocrine-Disrupting Chemicals: A Review of Existing Approaches and New Alternatives.
Environmental contaminants and child’s growth.
The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease.
BPA/Phenols/Phthalates
Systematic review and meta-analysis on the association between phthalates exposure and insulin resistance.
Persistent Organic Pollutants
Persistent Organic Pollutant-Mediated Insulin Resistance.
Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants.
Pesticides
Elucidating Conserved Transcriptional Networks Underlying Pesticide Exposure and Parkinson’s Disease: A Focus on Chemicals of Epidemiological Relevance.
Metals
Mercury-induced inflammation and autoimmunity.
The relationship between mercury exposure and epigenetic alterations regarding human health, risk assessment and diagnostic strategies.
Other Chemicals
Acrylamide: A review about its toxic effects in the light of Developmental Origin of Health and Disease (DOHaD) concept.
National Trends of Bladder Cancer and Trihalomethanes in Drinking Water: A Review and Multicountry Ecological Study.
Human exposures to rare earth elements: Present knowledge and research prospects.
Human Health Studies
BPA/Phenols
Serum Bisphenol A concentrations in men with idiopathic infertility.
Phthalates
Levels of phthalate acid esters and sex hormones and their possible sources in traffic-patrol policemen in Chongqing.
Prenatal and childhood exposure to phthalates and motor skills at age 11 years.
Early-life exposome and lung function in children in Europe: an analysis of data from the longitudinal, population-based HELIX cohort. [includes PFASs etc also]
Parabens/Triclosan/Antimicrobials
Early-life triclosan exposure and parent-reported behavior problems in 8-year-old children.
Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study.
Persistent Organic Pollutants
Pre-diagnostic serum concentrations of organochlorines and risk of acute myeloid leukemia: A nested case-control study in the Norwegian Janus Serum Bank Cohort.
Plasma levels of dichlorodiphenyldichloroethene (DDE) and dichlorodiphenyltrichloroethane (DDT) and survival following breast cancer in the Carolina Breast Cancer Study.
Quantitative bias analysis of the association of type 2 diabetes mellitus with 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153).
Perfluoroalkyl Substances
Perfluoroalkyl substances exposure and risk of polycystic ovarian syndrome related infertility in Chinese women.
Flame Retardants
Prenatal polybrominated diphenyl ethers exposure and anogenital distance in boys from a Shanghai birth cohort.
The association of urinary phosphorous-containing flame retardant metabolites and self-reported personal care and household product use among couples seeking fertility treatment.
Arsenic/Metals
Prenatal exposure to mercury in relation to infant infections and respiratory symptoms in the New Hampshire Birth Cohort Study.
Associations of multiple plasma metals with the risk of ischemic stroke: A case-control study.
Association between serum thallium in early pregnancy and risk of gestational diabetes mellitus: The Ma’anshan birth cohort study.
High serum arsenic and cardiovascular risk factors in patients undergoing continuous ambulatory peritoneal dialysis.
Mediating role of arsenic in the relationship between diet and pregnancy outcomes: prospective birth cohort in Bangladesh.
Serum Cadmium Level Is Positively Associated with Unruptured Intracranial Aneurysm Incidence.
Miscellaneous
Exposure to indoor endocrine disrupting chemicals and childhood asthma and obesity. [VOCs]
Laboratory Studies
BPA/Phenols
Systems analysis of the liver transcriptome in adult male zebrafish exposed to the non-ionic surfactant nonylphenol.
Neurobehavioral effects of bisphenol S exposure in early life stages of zebrafish larvae (Danio rerio).
Regulation of Gpr173 expression, a putative phoenixin receptor, by saturated fatty acid palmitate and endocrine-disrupting chemical bisphenol A through a p38-mediated mechanism in immortalized hypothalamic neurons.
Exposure to bisphenol A: current levels from food intake are toxic to human cells.
Effects of exogenous bisphenol A on the function of mitochondria in root cells of soybean (Glycine max L.) seedlings.
Cytological Evaluation of the Influence of High and Low Doses of Bisphenol a on an Erythroblastic Cell Line of Porcine Bone Marrow.
Phthalates
Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes.
Effects of perinatal di (2-ethylhexyl) phthalate exposure on thyroid function in rat offspring.
Phthalates affect the in vitro expansion of human hematopoietic stem cell.
Persistent Organic Pollutants
Persistent endocrine-disrupting chemicals found in human follicular fluid stimulate the proliferation of granulosa tumor spheroids via GPR30 and IGF1R but not via the classic estrogen receptors. [HCB, DDE, PCBs, PFASs]
Effects of PCB-77 in adult zebrafish after exposure during early life stages.
Toxicokinetics of Chiral PCB 136 and its Hydroxylated Metabolites in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase.
Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells.
Perfluoroalkyl Substances
Metabolomic responses to pre-chlorinated and final effluent wastewater with the addition of a sub-lethal persistent contaminant in Daphnia magna. [PFOS]
Low concentrations of perfluorooctane sulfonate repress osteogenic and enhance adipogenic differentiation of human mesenchymal stem cells.
Screening of potential PFOS alternatives to decrease liver bioaccumulation: Experimental and computational approaches.
Flame Retardants
Characterization of the Fundulus heteroclitus embryo transcriptional response and development of a gene expression-based fingerprint of exposure for the alternative flame retardant, TBPH (bis (2-ethylhexyl)-tetrabromophthalate).
Oxidative Stress, Induced by Sub-Lethal Doses of BDE 209, Promotes Energy Management and Cell Cycle Modulation in the Marine Fish Cell Line SAF-1.
The effects of decabromodiphenyl ether on glycolipid metabolism and related signaling pathways in mice.
Pesticides
Can atrazine loaded nanocapsules reduce the toxic effects of this herbicide on the fish Prochilodus lineatus? A multibiomarker approach.
Toxic effects of boscalid in adult zebrafish (Danio rerio) on carbohydrate and lipid metabolism.
Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure.
The case for thyroid disruption in early life stage exposures to thiram in zebrafish (Danio rerio).
Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte.
Arsenic/Metals
Arsenite suppresses NO production evoked by lipopolysaccharide and poly(I:C) via the suppression of interferon-β expression in RAW264.7 cells.
High-Protein Diet Ameliorates Arsenic-Induced Oxidative Stress and Antagonizes Uterine Apoptosis in Rats.
Modulation of the immune response and infection pattern to Leishmania donovani in visceral leishmaniasis due to arsenic exposure: An in vitro study.
Developmental neurotoxicity of inorganic arsenic exposure in Sprague-Dawley rats.
Daphnetin activates the Nrf2-dependent antioxidant response to prevent arsenic-induced oxidative insult in human lung epithelial cells.
Embryonic arsenic exposure reduces intestinal cell proliferation and alters hepatic IGF mRNA expression in killifish (Fundulus heteroclitus).
Proteomic Characterization of the Arsenic Response Locus in S. cerevisiae.
Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic.
Mixtures
Chronic exposure to a pollutant mixture at low doses led to tissue-specific metabolic alterations in male mice fed standard and high-fat high-sucrose diet. [BPA, phthalates, dioxin, PCBs]
Pharmaceuticals
Impact of Long-Term Exposure to 17α-Ethinylestradiol in the Live-Bearing Fish Heterandria formosa.
Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline.
Investigating tissue bioconcentration and the behavioural effects of two pharmaceutical pollutants on sea trout (Salmo trutta) in the laboratory and field.
Altered non-reproductive behavior and feminization caused by developmental exposure to 17α-ethinylestradiol persist to adulthood in three-spined stickleback (Gasterosteus aculeatus).
Context-specific behavioural changes induced by exposure to an androgenic endocrine disruptor.
Miscellaneous
Liver disorders related to exposure to gasoline fumes in male rats and role of fenugreek seed supplementation.
Cytotoxicity against fish and mammalian cell lines and endocrine activity of the mycotoxins beauvericin, deoxynivalenol and ochratoxin-A.
Characterization of leachates from waste landfill sites in a religious camp along Lagos-Ibadan expressway, Nigeria and its hepatotoxicity in rats.
Silver nanoparticles inhibit beige fat function and promote adiposity.
Enhancement of androgen transcriptional activation assay based on genome edited glucocorticoid knock out human prostate cancer cell line.
Wildlife/Environment/Exposure Studies
BPA/Phenols
Urinary levels, composition profile and cumulative risk of bisphenols in preschool-aged children from Nanjing suburb, China.
Phthalates
Quantification of polycyclic aromatic hydrocarbons and phthalic acid esters in deodorizer distillates obtained from soybean, rapeseed, corn and rice bran oils.
Development of magnetic solid phase microextraction method for determination of the endocrine disrupting chemicals leached from reused plastic bottles.
Assessment of phthalate ester residues and distribution patterns in Baijiu raw materials and Baijiu. [Baijiu = Chinese grain liquor]
Parabens/Triclosan/Antimicrobials
Parabens and their metabolite in surface water and sediment from the Yellow River and the Huai River in Henan Province: Spatial distribution, seasonal variation and risk assessment.
Persistent Organic Pollutants
Introducing of modeling techniques in the research of POPs in breast milk – A pilot study.
Preliminary assessment of exposure to persistent organic pollutants among pregnant women in Puerto Rico.
Concentrations of dioxins and furans in breast milk of women living near a hazardous waste incinerator in Catalonia, Spain.
Age-dependent human elimination half-lives of dioxin-like polychlorinated biphenyls derived from biomonitoring data in the general population.
Dioxins in Great Lakes fish: Past, present and implications for future monitoring.
Bioaccumulation of dichlorodiphenyltrichloroethanes (DDTs) in carp in a water/sediment microcosm: important role of sediment particulate matter and bioturbation.
Cytokine expression and lymphocyte proliferative capacity in diseased harbor porpoises (Phocoena phocoena) – Biomarkers for health assessment in wildlife cetaceans.
Where has the pollution gone? A survey of organic contaminants in Ho Chi Minh city / Saigon River (Vietnam) bed sediments.
Multi-residue screening of non-polar hazardous chemicals in green turtle blood from different foraging regions of the Great Barrier Reef.
Flame Retardants
Characterization of brominated, chlorinated, and phosphate flame retardants in San Francisco Bay, an urban estuary.
Arsenic/Metals
Transgenerational endocrine disruption: Does elemental pollution affect egg or nestling thyroid hormone levels in a wild songbird?
Impacts of Arsenic and Antimony Co-Contamination on Sedimentary Microbial Communities in Rivers with Different Pollution Gradients.
Arsenic accumulation in lettuce (Lactuca sativa L.) and broad bean (Vicia faba L.) crops and its potential risk for human consumption.
Appraising spatial variations of As, Fe, Mn and NO3 contaminations associated health risks of drinking water from Surma basin, Bangladesh.
Water management impacts the soil microbial communities and total arsenic and methylated arsenicals in rice grains.
Evaluation of plasma arsenicals as potential biomarkers of exposure to inorganic arsenic.
Toxicity of As in Crassostrea virginica (Gmelin, 1791) from the Northern Gulf of Mexico at the presence of Zn and its antioxidant defense mechanisms.
Is the Cooking Salt Safe in China? Assessment of Chemical Contaminants in Cooking Salt. [metals, phthalates]
Organotins
Preliminary studies about the role of physicochemical parameters on the organotin compound dynamic in a South American estuary (Bahía Blanca, Argentina).
Simultaneous determination of three organotin pesticides in fruits and vegetables by high-performance liquid chromatography-tandem mass spectrometry.
Miscellaneous
Toxicokinetics and bioaccumulation of polycyclic aromatic compounds in wood frog tadpoles (Lithobates sylvaticus) exposed to Athabasca oil sands sediment.
This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.
