New EDC articles, Apr. 24 – 30, 2019 – HEEDS

New EDC articles, Apr. 24 – 30, 2019

Post author:HEEDS
Post published:April 30, 2019
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Interesting Research of the Week, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.

Interesting Research of the Week

Socioeconomic position and exposure to multiple environmental chemical contaminants in six European mother-child cohorts.

Assessment of Glyphosate Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutations: Generational Toxicology.

Reviews

GRADE guidelines for environmental and occupational health: A new series of articles in Environment International.

Perinatal Exposure to Environmental Endocrine Disruptors in the Emergence of Neurodevelopmental Psychiatric Diseases: A Systematic Review.

Effects of single and combined toxic exposures on the gut microbiome: current knowledge and future directions.

Linking mitochondrial dysfunction to organismal and population health in context of environmental pollutants: Progress and considerations for mitochondrial adverse outcome pathways.

Autophagy in male reproduction.

Trends of electronic waste pollution and its impact on the global environment and ecosystem.

Pollutants released from the pulp paper industry: Aquatic toxicity and their health hazards.

Pesticides

A Pest to Mental Health? Exploring the Link between Exposure to Agrichemicals in Farmers and Mental Health.

Into the Weeds: Regulating Pesticides in Cannabis. [EHP Focus]

Air Pollution

Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose-Response Meta-Analysis.

Metals/Arsenic

Association of maternal arsenic exposure with birth size: A systematic review and meta-analysis.

Ideal Cereals With Lower Arsenic and Cadmium by Accurately Enhancing Vacuolar Sequestration Capacity.

A Systematic Review on Arsenic Bio-Availability in Human and Animals: Special Focus on the Rice-Human System.

Human Health Studies

Phenols

Anthropometric measures at age 3 years in associations with prenatal and postnatal exposures to chlorophenols.

Phthalates

Phthalate-associated hypertension in premature infants: a prospective mechanistic cohort study.

Phthalate exposure increases subclinical atherosclerosis in young population.

Persistent Organic Pollutants

Residue Levels of Organochlorine Pesticides in Breast Milk and Its Associations with Cord Blood Thyroid Hormones and the Offspring’s Neurodevelopment.

Chlorinated persistent organic pollutants and type 2 diabetes – A population-based study with pre- and post- diagnostic plasma samples.

Association of Exposure to Persistent Organic Pollutants With Mortality Risk: An Analysis of Data From the Prospective Investigation of Vasculature in Uppsala Seniors (PIVUS) Study.

Perfluoroalkyl Substances

Exposure to perfluoroalkyl substances (PFAS) and associations with thyroid parameters in First Nation children and youth from Quebec.

Pesticides

Comet Assay for Assessment of DNA Damage in Greenhouse Workers Exposed to Pesticides.

Animal production, insecticide use and self-reported symptoms and diagnoses of COPD, including chronic bronchitis, in the Agricultural Health Study.

Difference in Accidents, Health Symptoms, and Ergonomic Problems between Conventional Farmers Using Pesticides and Organic Farmers.

Investigation of pesticide exposure by genotoxicological, biochemical, genetic polymorphic and in silico analysis.

Arsenic/Metals

Peripheral neuropathy induced by drinking water contaminated with low-dose arsenic in Myanmar.

Higher risk of hyperglycemia with greater susceptibility in females in chronic arsenic-exposed individuals in Bangladesh.

Prenatal Cadmium Exposure Is Negatively Associated With Adiposity in Girls Not Boys During Adolescence.

Laboratory Studies

BPA/Phenols

Bisphenol A promotes the proliferation of leiomyoma cells by GPR30-EGFR signaling pathway.

Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison.

Comprehensive circRNA/miRNA/mRNA analysis reveals circRNAs protect against toxicity induced by BPA in GC-2 cells.

Parental perinatal exposure to bisphenol A reduces the threshold to disrupt blastocyst implantation via decreasing talin, occudin and E-cadherin levels.

Effects of nonylphenols on embryonic development and metamorphosis of Xenopus laevis: FETAX and amphibian metamorphosis toxicity test (OECD TG231).

Acute toxicity of bisphenol A and its structural analogues and transcriptional modulation of the ecdysone-mediated pathway in the brackish water flea Diaphanosoma celebensis.

Phthalates

The Effects of Mono-(2-Ethylhexyl) Phthalate (MEHP) on Human Estrogen Receptor (hER) and Androgen Receptor (hAR) by YES/YAS In Vitro Assay.

Mono-(2-ethylhexyl) phthalate aggravates inflammatory response via sirtuin regulation and inflammasome activation in RAW 264.7 cells.

Growth-promoting effects of low-level butyl benzyl phthalate exposure on human neuroblastoma SH-SY5Y cells.

Detection of Endogenous Phthalates in Bacterial Pathogens of Plants and Animals.

Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.

Dibutyl phthalate-induced activation of ROS and ERK1/2 causes hepatic and renal damage in Kunming mice.

Exposure to di-(2-ethylhexyl) phthalate transgenerationally alters anxiety-like behavior and amygdala gene expression in adult male and female mice.

Dibutyl phthalate impairs neural progenitor cell proliferation and hippocampal neurogenesis.

Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast.

Effects of the Dibutyl Phthalate (DBP) on the Expression and Activity of Aromatase in Human Granulosa Cell Line KGN.

Altered morphokinetics in equine embryos from oocytes exposed to DEHP during IVM.

Effects of di(2-etilhexil) phthalate on human umbilical artery.

[Effects of phthalate on pulmonary allergy of offspring during intrauterin and lactating exposure]. Chinese

Triclosan

Medaka (Oryzias latipes) Multigeneration Test with Triclosan.

Persistent Organic Pollutants

2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice.

2,3,7,8-tetrachloodibenzo-p-dioxin affects the differentiation of CD4 helper T cell.

Label-free and iTRAQ proteomics analysis in the liver of zebrafish (Danio rerio) following dietary exposure to the organochlorine pesticide dieldrin.

Oxidative stress and mitochondrial uncoupling protein 2 expression in hepatic steatosis induced by exposure to xenobiotic DDE and high fat diet in male Wistar rats.

Baseline bio-accumulation concentrations and resulting oxidative stress in Synodontis zambezensis after an acute laboratory exposure to 4,4′-DDT.

Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease.

C9-13 chlorinated paraffins cause immunomodulatory effects in adult C57BL/6 mice.

Perfluoroalkyl Substances

Unravelling the mechanisms of PFOS toxicity by combining morphological and transcriptomic analyses in zebrafish embryos.

PFOA and PFOS promote diabetic renal injury in vitro by impairing the metabolisms of amino acids and purines.

Flame Retardants

Cardiovascular toxicity of decabrominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in rats.

Acute exposure to triphenyl phosphate inhibits the proliferation and cardiac differentiation of mouse embryonic stem cells and zebrafish embryos.

Pesticides

Glyphosate induces toxicity and modulates calcium and NO signaling in zebrafish embryos.

Mancozeb impaired male fertility in rabbits with trials of glutathione detoxification.

Effect of Individual and Combined Treatments of Pesticide, Fertilizer, and Salt on Growth and Corticosterone Levels of Larval Southern Leopard Frogs (Lithobates sphenocephala).

Physiological traits of land snails Theba pisana as simple endpoints to assess the exposure to some pollutants.

Exposure to Roundup® affects behaviour, head regeneration and reproduction of the freshwater planarian Girardia tigrina.

Impact of chlorpyrifos on behavior and histopathological indices in different tissues of freshwater fish Channa punctatus (Bloch).

Curcumin Modulates Paraquat-Induced Epithelial to Mesenchymal Transition by Regulating Transforming Growth Factor-β (TGF-β) in A549 Cells.

Brain transcriptome of honey bees (Apis mellifera) exhibiting impaired olfactory learning induced by a sublethal dose of imidacloprid.

Toxicity of lead and mancozeb differs in two monophyletic Daphnia species.

Fate and effects of two pesticide formulations in the invertebrate Folsomia candida using a natural agricultural soil.

Innovative selection approach for a new antifungal agent mefentrifluconazole (Revysol®) and the impact upon its toxicity profile.

Oxidative stress, genotoxicity, biochemical and histopathological modifications induced by epoxiconazole in liver and kidney of Wistar rats.

Early Synaptic Alterations and Selective Adhesion Signaling in Hippocampal Dendritic Zones Following Organophosphate Exposure.

Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress.

Arsenic/Metals

Cyanidin-3-O-glucoside protects against cadmium-induced dysfunction of sex hormone secretion via the regulation of hypothalamus-pituitary-gonadal axis in male pubertal mice.

Laboratory bioassays on the response of honey bee (Apis mellifera L.) glutathione S-transferase and acetylcholinesterase to the oral exposure to copper, cadmium, and lead.

Inhibitory effect of cadmium exposure on digestive activity, antioxidant capacity and immune defense in the intestine of yellow catfish (Pelteobagrus fulvidraco).

Diphenyl diselenide dietary supplementation protects against methylmercury-chloride-induced immunotoxicity in the head kidney and spleen of grass carp (Ctenopharyngodon idella) via regulation of purinergic signaling and the NLRP3 inflammasome.

Microplastics

First evidence of protein modulation by polystyrene microplastics in a freshwater biological model.

Uptake and adverse effects of polyethylene terephthalate microplastics fibers on terrestrial snails (Achatina fulica) after soil exposure.

Significant decline of Daphnia magna population biomass due to microplastic exposure.

Screening

Improving the Utility of the Tox21 Dataset by Deep Metadata Annotations and Constructing Reusable Benchmarked Chemical Reference Signatures.

Miscellaneous

The Flavone Luteolin, an Endocrine Disruptor, Relaxed Male Guinea Pig Gallbladder Strips.

Applying sunscreens on earthworms: Molecular response of Eisenia fetida after direct contact with an organic UV filter.

Wildlife/Environment/Exposure Studies

Persistent Organic Pollutants

Spatial distribution, source identification, and potential risk assessment of toxic contaminants in surface waters from Yulin, China. [POPs and metals]

Accumulation of PCBs, PAHs, plasticizers and inorganic elements in Hexanchus griseus from the strait of Messina (Central Mediterranean sea).

Spatial distribution, source identification, and potential risk assessment of toxic contaminants in surface waters from Yulin, China.

Organochlorine pesticides air monitoring near a historical lindane production site in Spain.

Trophic position and individual feeding habits as drivers of differential PCB bioaccumulation in fish populations.

Dietary exposure and risk assessment of organochlorine pesticide residues in rural communities living within catchment areas of iSimangaliso World Heritage Site, South Africa.

Residue concentrations and profiles of PCDD/Fs in ash samples from multiple thermal industrial processes in Vietnam: Formation, emission levels, and risk assessment.

Accumulation pattern and possible adverse effects of organic pollutants in sediments downstream of combined sewer overflows.

High intake of persistent organic pollutants generated by a municipal waste incinerator by breastfed infants.

Health indicators and contaminant levels of a critically endangered species in the Gironde estuary, the European sturgeon. [metals, PCBs, OCPs, PBDEs]

Perfluoroalkyl Substances

Per- and polyfluoroalkyl substances (PFASs) in the blood of two colobine monkey species from China: Occurrence and exposure pathways.

Flame Retardants

Flame retardants and plasticizers in a Canadian waste electrical and electronic equipment (WEEE) dismantling facility.

Occurrence of organophosphate esters and their diesters degradation products in industrial wastewater treatment plants in China: Implication for the usage and potential degradation during production processing.

Decreasing but still high levels of halogenated flame retardants in wetland birds in central Spain.

Pesticides

Pharmaceuticals, herbicides, and disinfectants in agricultural water sources.

An integrated assessment and spatial-temporal variation analysis of neonicotinoids in pollen and honey from noncrop plants in Zhejiang, China.

Sub-lethal concentrations of neonicotinoid insecticides at the field level affect negatively honey yield: Evidence from a 6-year survey of Greek apiaries.

Neonicotinoids in raw, finished, and tap water from Wuhan, Central China: Assessment of human exposure potential.

Cumulative probabilistic risk assessment of triazole pesticides in Belgium from 2011-2014.

Screening of pesticides and veterinary drugs in small streams in the European Union by liquid chromatography high resolution mass spectrometry.

Pesticides use and exposure among yam farmers in the Nanumba traditional area of Ghana.

Fiproles in urban surface runoff: Understanding sources and causes of contamination.

Arsenic/Metals

Slimming to the Death: Herbalife®-Associated Fatal Acute Liver Failure-Heavy Metals, Toxic Compounds, Bacterial Contaminants and Psychotropic Agents in Products Sold in India.

Levels of heavy metals in the straightfin barb Enteromius paludinosus (Peters 1852) from River Malewa, Naivasha, Kenya.

Trends and Health Risks of Dissolved Heavy Metal Pollution in Global River and Lake Water from 1970 to 2017.

Exposure assessment for the abandoned metal mine area contaminated by arsenic.

Arsenic and trace metals in a large reservoir: Seasonal and spatial variations, source identification and risk assessment for both residential and recreational users.

Levels and determinants of adipose tissue cadmium concentrations in an adult cohort from Southern Spain.

Heavy metal distribution, translocation, and human health risk assessment in the soil-rice system around Dongting Lake area, China.

Effectiveness of Different Approaches to Arsenic Mitigation over 18 Years in Araihazar, Bangladesh: Implications for National Policy.

Microplastics

First record of characterization, concentration and distribution of microplastics in coastal sediments of an urban fjord in south west Norway using a thermal degradation method.

Microplastics biomonitoring in Australian urban wetlands using a common noxious fish (Gambusia holbrooki).

Source and potential risk assessment of suspended atmospheric microplastics in Shanghai.

Miscellaneous

Exposures in the City: Looking for Socioeconomic Patterns for the Urban Exposome.

Development of enterosorbents that can be added to food and water to reduce toxin exposures during disasters.

This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.