New EDC articles, Apr. 17 – 23, 2019 – HEEDS

New EDC articles, Apr. 17 – 23, 2019

Post author:HEEDS
Post published:April 23, 2019
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies.

Regulations/Policy

Linking Bisphenol S to Adverse Outcome Pathways Using a Combined Text Mining and Systems Biology Approach.

Reviews

Transgenerational effects of endocrine disrupting chemicals on male and female reproduction.

Role of Emerging Environmental Risk Factors in Thyroid Cancer: A Brief Review.

The Olfactory System of Zebrafish as a Model for the Study of Neurotoxicity and Injury: Implications for Neuroplasticity and Disease.

Environmental Health Indicators for China: Data Resources for Chinese Environmental Public Health Tracking.

Environmental DNA Shaping A New Era of Ecotoxicological Research.

BPA/Phenols/Phthalates

The association between prenatal exposure to phthalates and cognition and neurobehavior of children-evidence from birth cohorts.

Arsenic

Metabolic and epigenetic reprogramming in the arsenic-induced cancer stem cells.

Pesticides

Exposure to neuroactive non-organochlorine insecticides, and diabetes mellitus and related metabolic disturbances: Protocol for a systematic review and meta-analysis.

Chronic Kidney Disease in Agricultural Communities.

Distribution of toxicity values across different species and modes of action of pesticides from PESTIMEP and PPDB databases.

Gut microbiota: An underestimated and unintended recipient for pesticide-induced toxicity.

Human Health Studies

BPA/Phenols

Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.

Phthalates

Phthalate Exposure and Breast Cancer Incidence: A Danish Nationwide Cohort Study.

Persistent Organic Pollutants

Genes associated with Parkinson’s disease respond to increasing polychlorinated biphenyl levels in the blood of healthy females.

Associations between polychlorinated dibenzo-dioxins and polychlorinated dibenzo-furans exposure and oxidatively generated damage to DNA and lipid.

Pre-diagnostic blood levels of organochlorines and risk of non-Hodgkin lymphoma in three prospective cohorts in China and Singapore.

Perfluoroalkyl Substances

Perfluorinated alkylated substances serum concentration and breast cancer risk: Evidence from a nested case-control study in the French E3N cohort.

Flame Retardants

Associations between urinary organophosphate ester metabolites and measures of adiposity among U.S. children and adults: NHANES 2013-2014.

Pesticides

Association of Occupational Pesticide Exposure With Immunochemotherapy Response and Survival Among Patients With Diffuse Large B-Cell Lymphoma.

Organochlorine and organophosphorous pesticides may induce colorectal cancer; A case-control study.

Organochlorine and organophosphorus pesticides and bladder cancer: A case-control study.

Chronic pesticide mixture exposure including paraquat and respiratory outcomes among Colombian farmers.

Arsenic/Metals

Water Contaminant Levels Interact with Parenting Environment to Predict Development of Depressive Symptoms in Adolescents.

Manganese exposure and working memory-related brain activity in smallholder farmworkers in Costa Rica: Results from a pilot study.

Maternal heavy metal exposure, thyroid hormones, and birth outcomes: a prospective cohort study.

A curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager.

Serum Selenium and Lead Levels: a Possible Link with Diabetes and Associated Proteinuria.

Miscellaneous

Influence of the Urban Exposome on Birth Weight.

Laboratory Studies

BPA/Phenols

Bisphenol-A induced oxidative stress, inflammatory gene expression, and metabolic and histopathological changes in male Wistar albino rats: protective role of boron.

Transcriptional Analysis of Chlorella Pyrenoidosa Exposed to Bisphenol A.

Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats.

Design, synthesis, and biological evaluation of lipophilically modified bisphenol Z derivatives.

Potential Toxic Effect of Bisphenol A on the Cardiac Muscle of Adult Rat and the Possible Protective Effect of Omega-3: A Histological and Immunohistochemical Study.

Phthalates

Endoplasmic reticulum stress, a novel significant mechanism responsible for DEHP-induced increased distance between seminiferous tubule of mouse testis.

Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats.

Mono-2-ethylhexyl phthalate induces the expression of genes involved in fatty acid synthesis in HepG2 cells.

Fibroblast growth factor 21 secretion enhances glucose uptake in mono(2-ethylhexyl)phthalate-treated adipocytes.

Effects of di-n-butyl phthalate on photosynthetic performance and oxidative damage in different growth stages of wheat in cinnamon soils.

Persistent Organic Pollutants

Concentration dependence of human and mouse aryl hydrocarbon receptor responsiveness to polychlorinated biphenyl exposures: Implications for aroclor mixtures.

Protective effects of genistein on cytochrome P-450 and vitellogenin expression in liver of zebrafish after PCB-126 exposure.

PCB52 induces hepatotoxicity in male offspring through aggravating loss of clearance capacity and activating the apoptosis: Sex-biased effects on rats.

Biochanin A prevents 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced adipocyte dysfunction in cultured 3T3-L1 cells.

Perfluoroalkyl Substances

Effects of perfluorooctanoic acid on stem Leydig cell functions in the rat.

Role of astrocytes-derived D-serine in PFOS-induced neurotoxicity through NMDARs in the rat primary hippocampal neurons.

Flame Retardants

OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway.

Pesticides

Pregnane X receptor mediates steatotic effects of propiconazole and tebuconazole in human liver cell lines.

Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies.

Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats.

Glyphosate, but not its metabolite AMPA, alters the honeybee gut microbiota.

Assessment of acute toxicity and biochemical responses to chlorpyrifos, cypermethrin and their combination exposed earthworm, Eudrilus eugeniae.

Protective effects of resveratrol on biomarkers of oxidative stress, biochemical and histopathological changes induced by sub-chronic oral glyphosate-based herbicide in rats.

Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries In Mice by Modifying Oxidative Stress and Apoptosis.

Gene expression, genotoxicity, and physiological responses in an Amazonian fish, Colossoma macropomum (CUVIER 1818), exposed to Roundup® and subsequent acute hypoxia.

Doxycycline alleviates paraquat-induced acute lung injury by inhibiting neutrophil-derived matrix metalloproteinase 9.

Arsenic/Metals

Toxicological effects of toxic metals (cadmium and mercury) on blood and the thyroid gland and pharmacological intervention by vitamin C in rabbits.

Perinatal Lead (Pb) Exposure and Cortical Neuron-Specific DNA Methylation in Male Mice.

Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mice.

Chronic low-level cadmium exposure in rats affects cytokine production by activated T cells.

Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.

Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS.

Organotins

Effects of Tributyltin (TBT) on Rat Bone and Mineral Metabolism.

Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans.

Microplastics

Microplastic-Contaminant Interactions: Influence of Non-Linearity and Coupled Mass Transfer.

Pharmaceuticals

Flutamide-induced alterations in transcriptional profiling of neonatal porcine ovaries.

Transcriptomic analysis of the impacts of ethinylestradiol (EE2) and its consequences for proliferative kidney disease outcome in rainbow trout (Oncorhynchus mykiss).

Mixtures

Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays.

Adverse and hormetic effects in rats exposed for 12 months to low dose mixture of 13 chemicals: RLRS part III.

Joint toxic effects of cadmium and four pesticides on the earthworm (Eisenia fetida).

Miscellaneous

3-Monochloropropane-1, 2-diol causes irreversible damage to reproductive ability independent of hormone changes in adult male rats.

The flavonoid chrysin protects against zearalenone induced reproductive toxicity in male mice.

Using a hybrid read-across method to evaluate chemical toxicity based on chemical structure and biological data.

Wildlife/Environment/Exposure Studies

BPA/Phenols

Investigating the role of colloids on the distribution of bisphenol analogues in surface water from an ecological demonstration area, China.

Atmospheric levels of BPA associated with particulate matter in an urban environment.

Phthalates

Distribution and Dietary Predictors of Urinary Phthalate Metabolites among Pregnant Women in Shanghai, China.

Determinants of phthalate exposure and risk assessment in children from Poland.

Persistent Organic Pollutants

Polycyclic aromatic hydrocarbons in breast milk of obese vs normal women: Infant exposure and risk assessment.

Biomonitoring Organochlorine Pesticides in Didelphis virginiana from Yucatan, Mexico by GC-ECD.

Occurrence and Potential Risk of Polychlorinated Biphenyls in Surface Soils from the Yellow River Delta Natural Reserve, China.

Male workers’ exposure characteristics of ΣPCDD/F from a municipal solid waste incinerator in south China through hair analysis.

Elevated atmospheric CO2 might increase the health risk of long-term ingestion of leafy vegetables cultivated in residual DDT polluted soil.

Background levels of dioxin-like polychlorinated biphenyls (dlPCBs), polychlorinated, polybrominated and mixed halogenated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, PBDD/Fs & PXDD/Fs) in sera of pregnant women in Accra, Ghana.

PCB Emissions from Paint Colorants.

Organochlorine pesticides in the soils from Benevento provincial territory, southern Italy: Spatial distribution, air-soil exchange, and implications for environmental health.

Wax esters of uropygial gland secretion as biomarkers of endocrine disruption in birds exposed to treated sewage water.

Perfluoroalkyl Substances

Multiple crop bioaccumulation and human exposure of perfluoroalkyl substances around a mega fluorochemical industrial park, China: Implication for planting optimization and food safety.

Levels, spatial distribution and isomer profiles of perfluoroalkyl acids in soil, groundwater and tap water around a manufactory in China.

Identification of Per- and Polyfluoroalkyl Substances in the Cape Fear River by High Resolution Mass Spectrometry and Nontargeted Screening.

Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances.

Determination of 20 perfluoroalkyl substances in greenhouse vegetables with a modified one-step pretreatment approach coupled with ultra performance liquid chromatography tandem mass spectrometry(UPLC-MS-MS).

Temporal trends and sediment-water partitioning of per- and polyfluoroalkyl substances (PFAS) in lake sediment.

Flame Retardants

Halogenated flame retardants in mangrove sediments from the Pearl River Estuary, South China: Comparison with historical data and correlation with microbial community.

Analysis of brominated and chlorinated flame retardants, organophosphate esters, and polycyclic aromatic hydrocarbons in silicone wristbands used as personal passive samplers.

Stereoisomer-specific occurrence, distribution, and fate of chiral brominated flame retardants in different wastewater treatment systems in Hong Kong.

A preliminary screening of HBCD enantiomers transported by microplastics in wastewater treatment plants.

Polybrominated diphenyl ethers and biphenyl in serum – time trend study from the national health and nutrition examination survey for years 2005/06 through 2013/14.

Polyurethane heat preservation materials: The significant sources of organophosphorus flame retardants.

Concentrations of selected chemicals in indoor air from Norwegian homes and schools.

Pesticides

Dietary risk evaluation of tetraconazole and bifenazate residues in fresh strawberry from protected field in North China.

Arsenic/Metals

Chronic arsenic poisoning from traditional Chinese medicine.

Potentially toxic elements (PTEs) and polycyclic aromatic hydrocarbons (PAHs) in fish and prawn in the Persian Gulf, Iran.

Arsenic in Rice Bran Products: In Vitro Oral Bioaccessibility, Arsenic Transformation by Human Gut Microbiota, and Human Health Risk Assessment.

Modifying the Parboiling of Rice to Remove Inorganic Arsenic, While Fortifying with Calcium.

Bioaccumulation and human health implications of essential and toxic metals in freshwater products of Northeast China.

Correlation of arsenic level in drinking water and hair of male respondents of district Sheikhupura.

Fractions and colloidal distribution of arsenic associated with iron oxide minerals in lead-zinc mine-contaminated soils: Comparison of tailings and smelter pollution.

Inorganic arsenic content in Ecuadorian rice-based products.

Arsenic, Cadmium, Lead, and Mercury Concentrations in the Livers of Free-Ranging Common Garter Snakes (Thamnophis sirtalis) from Minnesota, USA.

Microplastics

Biodynamics of mercury in mussel tissues as a function of exposure pathway: natural vs microplastic routes.

Microplastic pollution in streams spanning an urbanisation gradient.

Distribution characteristics of microplastics in the seawater and sediment: A case study in Jiaozhou Bay, China.

This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.