EDC Science Weekly, Oct. 7-13, 2020 – HEEDS

EDC Science Weekly, Oct. 7-13, 2020

Post author:HEEDS
Post published:October 13, 2020
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Events,Commentaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Webinars

Oct 14:Non-Toxic: Guide to Living Healthy in a Chemical World

Oct. 29: Generation Chemical: How Environmental Exposures are Affecting Reproductive Health and Development

Commentarie

COVID-19 and clean air: an opportunity for radical change [comment in The Lancet]

Phthalates and Autistic Traits: Exploring the Association between Prenatal Exposures and Child Behavior. [Science Selection in EHP]

PFAS and Miscarriage in Humans: Expanding a Sparse Evidence Base. [Science Selection in EHP]

Letter to the Editor from Dorota Napierska et al: Unwitting Accomplices: Endocrine Disruptors Confounding Clinical Care.
Response Letter to the Editor from Napierska: “Unwitting Accomplices: Endocrine Disruptors Confounding Clinical Care”.

Reviews

Numerous EDCs

Interactions between environmental pollutants and dietary nutrients: current evidence and implications in epidemiological research.

Endocrine-disrupting chemicals and breastfeeding duration: a review.

An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment.

Environmental toxicant exposure and menstrual cycle length.

Phthalates

Effect of environmental contamination on female and male gametes – A lesson from bovines.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Are Persistent Organic Pollutants Linked to Lipid Abnormalities, Atherosclerosis and Cardiovascular Disease? A Review.

Perfluoroalkyl Substances

Reductive Defluorination and Mechanochemical Decomposition of Per- and Polyfluoroalkyl Substances (PFASs): From Present Knowledge to Future Remediation Concepts.

Potentially Toxic Elements

Heavy metals in indoor dust: Spatial distribution, influencing factors, and potential health risks.

Arsenic in shellfish: A systematic review of its dynamics and potential health risks.

Microplastics

A critical review of interactions between microplastics, microalgae and aquatic ecosystem function.

Plastic in agricultural soils – A global risk for groundwater systems and drinking water supplies? – A review.

Air Pollution

SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection?

Effects of PM_2.5 exposure on reproductive system and its mechanisms.

Long-term exposure to NO₂ and O₃ and all-cause and respiratory mortality: A systematic review and meta-analysis.

Pharmaceuticals/Personal Care Products

A review of the biotransformations of priority pharmaceuticals in biological wastewater treatment processes.

Miscellaneous

Risks of organic UV filters: a review of environmental and human health concern studies.

Co-Occurrence of Cyanobacteria and Cyanotoxins with Other Environmental Health Hazards: Impacts and Implications.

A critical review on the detection, occurrence, fate, toxicity, and removal of cannabinoids in the water system and the environment.

Advances and novel developments in environmental influences on the development of atopic diseases.

Human Health Studies

Perfluoroalkyl Substances

PFAS concentration during pregnancy in relation to cardiometabolic health and birth outcomes.

Pesticides

Household insecticide use and urinary 3-phenoxybenzoic acid levels in an elder population: a repeated measures data.

Longitudinal Study of Thyroid Hormones between Conventional and Organic Farmers in Thailand.

Parkinson Disease and Occupational and Environmental Exposure to Pesticides in a Region of Intense Agribusiness Activity in Brazil: A Case-Control Study.

Potentially Toxic Elements

Metal(loid)s role in the pathogenesis of amyotrophic lateral sclerosis: Environmental, epidemiological, and genetic data.

Plasma titanium level is positively associated with metabolic syndrome: A survey in China’s heavy metal polluted regions.

Early-Life Dietary Cadmium Exposure and Kidney Function in 9-Year-Old Children from the PROGRESS Cohort.

Air Pollution

Breast cancer among Danish women occupationally exposed to diesel exhaust and polycyclic aromatic hydrocarbons, 1964-2016.

Personal exposure to fine particulate air pollutants impacts blood pressure and heart rate variability.

Effects of long-term exposure to air pollution on all-cause mortality and cause-specific mortality in seven major cities of South Korea: Korean National Health and Nutritional Examination Surveys with mortality follow-up.

Associations between short-term exposure to PM2.5 and stroke incidence and mortality in China: A case-crossover study and estimation of the burden.

The determinants of COVID-19 case fatality rate (CFR) in the Italian regions and provinces: An analysis of environmental, demographic, and healthcare factors.

Personal PM_2.5 exposure and lung function: Potential mediating role of systematic inflammation and oxidative damage in urban adults from the general population.

Polycyclic aromatic hydrocarbons in particulate matter and serum club cell secretory protein change among schoolchildren: a molecular epidemiology study.

Ambient air pollution exposure during pregnancy and gestational diabetes mellitus in Shenyang, China: a prospective cohort study.

Associations between PM₁ exposure and daily emergency department visits in 19 hospitals, Beijing.

Associations between air pollution and outpatient visits for arrhythmia in Hangzhou, China.

Temporal and spatial effect of air pollution on hospital admissions for myocardial infarction: a case-crossover study.

Fine Particulate Matter Exposure and Cancer Incidence: Analysis of SEER Cancer Registry Data from 1992-2016.

Miscellaneous

Trimester-Specific Blood Trihalomethane and Urinary Haloacetic Acid Concentrations and Adverse Birth Outcomes: Identifying Windows of Vulnerability during Pregnancy. [disinfection byproducts]

Laboratory Studies

BPA/Phenols

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

Bisphenol A impaired cell adhesion by altering the expression of adhesion and cytoskeleton proteins on human podocytes.

In vitro effects of selected endocrine disruptors (DEHP, PCB118, BPA) on narrow-clawed crayfish (Astacus leptodactylus) primary cells.

Phthalates

Activation of forkhead box O3a by mono(2-ethylhexyl)phthalate and its role in protection against mono(2-ethylhexyl)phthalate-induced oxidative stress and apoptosis in human cardiomyocytes.

Effects of Phthalate Esters on Human Myometrial and Fibroid Cells: Cell Culture and NOD-SCID Mouse Data.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Effects of PCB126 on Adipose-to-Muscle Communication in an in Vitro Model.

Nontarget analysis reveals gut microbiome-dependent differences in the fecal PCB metabolite profiles of germ-free and conventional mice.

Telomeres as targets for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) in rats.

Natural organic matter does not diminish the mammalian bioavailability of 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Perfluoroalkyl Substances

Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA).

Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons.

Effect of perfluorohexane sulfonate on pig oocyte maturation, gap-junctional intercellular communication, mitochondrial membrane potential and DNA damage in cumulus cells in vitro.

Pesticides

Co-exposure to deltamethrin and thiacloprid induces cytotoxicity and oxidative stress in human lung cells.

Transcriptome analysis of fetal rat testis following intrauterine exposure to the azole fungicides triticonazole and flusilazole reveals subtle changes despite adverse endocrine effects.

Exposure to hydrocarbons and chlorpyrifos alters the expression of nuclear receptors and antioxidant, detoxifying, and immune response proteins in the liver of the rainbow trout, Oncorhynchus mykiss.

Chronic trichlorfon stress induces differential transcriptome expression and interferes with multifunctional pathways in the brain of Rana chensinensis.

A single dose of the organophosphate triazophos induces fear extinction deficits accompanied by hippocampal acetylcholinesterase inhibition.

Nano selenium protects against deltamethrin-induced reproductive toxicity in male rats.

Potentially Toxic Elements

Low dose lead exposure induces alterations on heterochromatin hallmarks persisting through SH-SY5Y cell differentiation.

Effects of environmental metals on mitochondrial bioenergetics of the CD-1 mice pancreatic beta-cells.

Microplastics/Nanoparticles

Interacting effects of simulated eutrophication, temperature increase, and microplastic exposure on Daphnia.

Toxicological alterations induced by subacute exposure of silver nanoparticles in Wistar rats.

Synergistic Effects of Selenium and Magnesium Nanoparticles on Growth, Digestive Enzymes, Some Serum Biochemical Parameters and Immunity of Asian Sea Bass (Lates calcarifer).

Pharmaceuticals/Personal Care Products

Toxicological outcome of exposure to psychoactive drugs carbamazepine and diazepam on non-target insect Nauphoeta cinerea.

Mixtures

Increased apoptosis, reduced Wnt/β-catenin signaling, and altered tail development in zebrafish embryos exposed to a human-relevant chemical mixture. [phthalates, triclosan, PFAS]

Miscellaneous

17α-ethinylestradiol and 4-tert-octylphenol concurrently disrupt the immune response of common carp.

Exposure/Environment Studies

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Distribution characteristics and environmental fate of PCBs in marine sediments at different latitudinal regions: Insights from congener profiles.

Life cycle bioenergetics of the gray seal (Halichoerus grypus) in the Baltic Sea: Population response to environmental stress.

Lipid metabolites as indicators of body condition in highly contaminant-exposed belugas from the endangered St. Lawrence Estuary population (Canada).

Perfluoroalkyl Substances

Per- and Polyfluoroalkyl Substances (PFAS) in Surface Water Near US Air Force Bases: Prioritizing Individual Chemicals and Mixtures for Toxicity Testing and Risk Assessment.

Identifying and Managing Aqueous Film-Forming Foam (AFFF)-Derived PFAS in the Environment.

Consumption of freshwater fish: a variable but significant risk factor for PFOS exposure.

Diet Shifts Explain Temporal Trends of Pollutant Levels in Indo-Pacific Humpback Dolphins (Sousa chinensis) from the Pearl River Estuary, China.

Flame Retardants

Legacy and alternative halogenated flame retardants in Lake Geneva fish.

Pesticides

Toxic compounds in herbicides without glyphosate.

Estimating human exposure to pyrethroids’ mixtures from biomonitoring data using physiologically based pharmacokinetic modeling.

Exposure to pesticides in bats.

Potentially Toxic Elements

Temporal variation of total mercury levels in the hair of pregnant women from the Maternal-Infant Research on Environmental Chemicals (MIREC) study.

Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden- a 23 year long temporal trend study.

A Comprehensive Risk Assessment of Toxic Elements in International Brands of Face Foundation Powders.

Heavy metal pollution and risk assessment by the battery of toxicity tests.

Heavy metal accumulation in two synanthropic avian species in Sri Lanka.

Potential Ecological Risk of Heavy Metals in a Typical Tributary of the Three Gorges Reservoir.

Brown watersnakes (Nerodia taxispilota) as bioindicators of mercury contamination in a riverine system.

Microplastics

Electric clothes dryers: An underestimated source of microfiber pollution.

The global biological microplastic particle sink.

Microplastics in freshwater and wild fishes from Lijiang River in Guangxi, Southwest China.

Air Pollution

Toward Environmental Justice in Civic Science: Youth Performance and Experience Measuring Air Pollution Using Moss as a Bio-Indicator in Industrial-Adjacent Neighborhoods.

Household and personal air pollution exposure measurements from 120 communities in eight countries: results from the PURE-AIR study.

Pre-to-post lockdown impact on air quality and the role of environmental factors in spreading the COVID-19 cases – a study from a worst-hit state of India.

Mixtures

Biomarker Responses of the Clams Ruditapes decussatus Exposed to a Complex Mixture of Environmental Stressors Under the Influence of an Urban Wastewater Treatment Plant.

Emerging organic contaminants in groundwater under a rapidly developing city (Patna) in northern India dominated by high concentrations of lifestyle chemicals.

Miscellaneous

Sustaining a nurse-led community partnership to promote environmental justice.

Biomonitoring of polycyclic aromatic hydrocarbons in the urine of lactating mothers: Urinary levels, association with lifestyle factors, and risk assessment.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sa…@healthandenvironment.org and ask to join the group EDC_re…@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.