EDC Science Weekly, Mar. 24 – 30, 2023

Post author:HEEDS
Post published:March 30, 2023
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Highlights: Series in The Lancet on the Commercial determinants of health; the Minderoo-Monaco commission on plastics; Human studies on PFAS and diabetes, ADHD, cancer, the liver, kidney, and thyroid…

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Webinar Mar. 31 11am ET: Pregnancy PFAS Exposure and Later-Life Maternal Cardiometabolic Health (this is the actual zoom link)

Apr. 11: Intersectoral Centre for Endocrine Disruptor Analysis (ICEDA) Awards Conference

Webinar April 13: Long-term Health Effects of Childhood Glyphosate Exposure (EDC Strategies Partnership)

For more events, see the March edition of HEEDS News

Regulations/Policy

Commercial determinants of health: future directions– one of many articles in a series in The Lancet

The Minderoo-Monaco Commission on Plastics and Human Health– a Special Collection in the Annals of Global Health [see the overall review article, an editorial, and a related article in Environmental Health News]

Persistent chemicals, persistent activism: scientific opportunity structures and social movement organizing on contamination by per-and polyfluoroalkyl substances

A Horizon Scan to support Chemical Pollution related policymaking for sustainable and climate resilient economies.

Impacts of emissions policies on future UK mortality burdens associated with air pollution.

Methods/Tools/Screening

Identification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study.

Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.

Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals.

Inadequate Definition of the Limit of Quantification Applied for the Quantification of Perfluoroalkyl Substances in Food by LC-MS/MS May Compromise the Reliability of the Data Requested by the European Regulation.

An innovative index to incorporate transcriptomic data into weight of evidence approaches for environmental risk assessment.

Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish.

Cuttlefish color change as an emerging proxy for ecotoxicology.

Triazine Herbicides Risk Management Strategies on Environmental and Human Health Aspects Using In-Silico Methods.

Commentaries

Editorial: Exploring impacts of combined exposures to particles and chemicals on immune reactions across living organisms. [intro to a research topic in Frontiers in Toxicology]

Nanoparticles in the Environment and Nanotoxicology. [intro to a research topic in Nanomaterials]

Molecular Mechanism of Action of Neonicotinoid Insecticides. [intro to a special issue in the International Journal of Molecular Sciences]

Emerging Research Needs for Characterizing the Risks of Global Lithium Pollution under Carbon Neutrality Strategies.

Manufactured doubt and the EPA 2020 chrysotile asbestos risk assessment.

Reviews

Numerous Chemicals/Mixtures

Interventions to Reduce Exposure to Synthetic Phenols and Phthalates from Dietary Intake and Personal Care Products: a Scoping Review.

Inherited Epigenetic Hallmarks of Childhood Obesity Derived from Prenatal Exposure to Obesogens.

Endocrine-Disrupting Chemicals and Disease Endpoints.

Endocrine Disruptor Compounds in Environment: Focus on Women’s Reproductive Health and Endometriosis.

Exposure to environmental chemicals and cancer risk: epidemiological evidence from Japanese studies.

BPA/Phenols

Current Evidence on Bisphenol A Exposure and the Molecular Mechanism Involved in Related Pathological Conditions.

Parabens/Triclosan/Antimicrobials

Adverse effects of triclosan exposure on health and potential molecular mechanisms.

Perfluoroalkyl Substances

Occupational exposure to per- and polyfluoroalkyl substances: a scope review of the literature from 1980-2021.

Flame Retardants

A Review on Tetrabromobisphenol A: Human Biomonitoring, Toxicity, Detection and Treatment in the Environment.

Pesticides

Are Botanical Biopesticides Safe for Bees (Hymenoptera, Apoidea)?

Organophosphate-Pesticide-Mediated Immune Response Modulation in Invertebrates and Vertebrates.

Metals/Metalloids

Pancreas-Liver-Adipose Axis: Target of Environmental Cadmium Exposure Linked to Metabolic Diseases.

Interaction of Metals, Menopause and COVID-19-A Review of the Literature

Microplastics/Nanomaterials

Transport of microplastics in the body and interaction with biological barriers, and controlling of microplastics pollution.

Organismal response to micro(nano)plastics at environmentally relevant concentrations: Toxicity and the underlying mechanisms.

Microplastics in water systems: A review of their impacts on the environment and their potential hazards.

Nanoplastics Toxicity Specific to Liver in Inducing Metabolic Dysfunction-A Comprehensive Review.

Biogenic metallic nanoparticles as enzyme mimicking agents.

Microfluidics as a Ray of Hope for Microplastic Pollution.

Pharmaceuticals/Personal Care Products

Do Synthetic Fragrances in Personal Care and Household Products Impact Indoor Air Quality and Pose Health Risks?

Miscellaneous

Analysis, environmental occurrence, fate and potential toxicity of tire wear compounds 6PPD and 6PPD-quinone.

Human Health Studies

Numerous Chemicals/Mixtures

Association of the urinary polycyclic aromatic hydrocarbons with sex hormones stratified by menopausal status older than 20 years: a mixture analysis.

Associations of perchlorate, nitrate, and thiocyanate with metabolic syndrome and its components among US adults: A cross-sectional study from NHANES.

Influence of Environmental Exposure to Steel Waste on Endocrine Dysregulation and PER3 Gene Polymorphisms.

Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.

BPA/Phenols

The associations between concentrations of gestational bisphenol analogues and thyroid related hormones in cord blood: A prospective cohort study.

Phthalates

Oxidative stress mediates the associations between phthalate exposures and thyroid cancer/benign nodule risk.

Individual and joint effects of phthalates exposure on the risk of early miscarriage.

Phthalate mixtures and insulin resistance: an item response theory approach to quantify exposure burden to phthalate mixtures.

DNA Hypomethylation Is Associated with Increased Inflammation in Peripheral Blood Neutrophils of Children with Autism Spectrum Disorder: Understanding the Role of Ubiquitous Pollutant Di(2-ethylhexyl) Phthalate.

Association between phthalates and sleep problems in the U.S. adult females from NHANES 2011-2014.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Dietary intake of polychlorinated dibenzo-p-dioxins and furans, adiposity and obesity status.

Perfluoroalkyl Substances

Occurrence of legacy and alternative per- and polyfluoroalkyl substances in serum from high exposure population and their disrupting effects on serum lipids and thyroid function.

Associations between per- and polyfluoroalkyl substances (PFAS) and diabetes in two population-based cohort studies from Sweden.

Exposure to per- and polyfluoroalkyl substances in early pregnancy, risk of gestational diabetes mellitus, potential pathways, and influencing factors in pregnant women: A nested case-control study.

Association between early-childhood exposure to perfluoroalkyl substances and ADHD symptoms: A prospective cohort study.

A prospective nested case-control study of serum concentrations of per- and polyfluoroalkyl substances and aggressive prostate cancer risk.

The variable associations between PFASs and biological aging by sex and reproductive stage in NHANES 1999-2018.

Mediation effects of DNA methylation and hydroxymethylation on birth outcomes after prenatal per- and polyfluoroalkyl substances (PFAS) exposure in the Michigan mother-infant Pairs cohort.

Association of per- and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults.

Exposure to perfluoroalkyl and polyfluoroalkyl substances and estimated glomerular filtration rate in adults: a cross-sectional study based on NHANES (2017-2018).

The Association of Combined Per- and Polyfluoroalkyl Substances and Metals with Allostatic Load Using Bayesian Kernel Machine Regression.

Kinetics of Excretion of the Perfluoroalkyl Surfactant cC₆O₄ in Humans.

Unveiling Distribution of Per- and Polyfluoroalkyl Substances in Matched Placenta-Serum Tetrads: Novel Implications for Birth Outcome Mediated by Placental Vascular Disruption.

Flame Retardants

A preliminary report on the association between maternal serum organophosphate ester concentrations and gestational diabetes mellitus.

Associations of brominated flame retardants exposure with chronic obstructive pulmonary disease: A US population-based cross-sectional analysis.

Early-life exposure to a mixture of organophosphate esters and child behavior.

Pesticides

Influence of exposure to pesticides on telomere length and pregnancy outcome: Diethylphosphates but not Dimethylphosphates are associated with accelerated telomere attrition in a Palestinian cohort.

Metals/Metalloids

Multiple exposures to heavy metals and changes in steroid hormones production in 4-year-old children.

The Folic Acid and Creatine Trial: Treatment Effects of Supplementation on Arsenic Methylation Indices and Metabolite Concentrations in Blood in a Bangladeshi Population.

Association of genetic polymorphisms in detoxifying systems and urinary metal(loid) levels with excess body weight among Spanish children: A proof-of-concept study.

Arsenic exposure alters the expression of genes related to metabolic diseases in differentiated adipocytes and in newborns and children.

Associations of metal mixtures with metabolic-associated fatty liver disease and non-alcoholic fatty liver disease: NHANES 2003-2018.

Association of urinary metal levels with metabolic syndrome in coal workers.

Multiple metal exposure and metabolic syndrome in elderly individuals: A case-control study in an active mining district, Northwest China.

Combined Exposure to Multiple Metals and Kidney Function in a Midlife and Elderly Population in China: A Prospective Cohort Study.

Higher Levels of Blood Selenium are Associated with Higher Levels of Serum Lipid Profile in US Adults with CKD: Results from NHANES 2013-2018.

[Association between urinary arsenic level and serum testosterone in Chinese men aged 18 to 79 years]. [in Chinese]

Air Pollution

Air Pollution and Mortality at the Intersection of Race and Social Class.

Preterm birth and term low birth weight associated with wildfire-specific PM_2.5: A cohort study in New South Wales, Australia during 2016-2019.

Associations between maternal exposure to ambient air pollution and very low birth weight: A birth cohort study in Chongqing, China.

Exposure to ultrafine particles and cognitive decline among older people in the United States.

Comparison of traditional cox regression and causal modeling to investigate the association between long-term air pollution exposure and natural-cause mortality within European cohorts.

Alterations to biomarkers related to long-term exposure to diesel exhaust at concentrations below occupational exposure limits in the European Union and the USA.

Miscellaneous

The association of prenatal amniotic sex hormones and digit ratio (2D:4D) in children aged 5 to 70 months: A longitudinal study.

The Environmental influences on Child Health Outcomes (ECHO)-wide Cohort.

Laboratory Studies

Numerous Chemicals/Mixtures

Gestational and Lactational Co-Exposure to DEHP and BPA Impairs Hepatic Function via PI3K/AKT/FOXO1 Pathway in Offspring.

Combined effects of climate change and environmentally relevant mixtures of endocrine disrupting compounds on the fitness and gonads’ maturation dynamics of Nucella lapillus (Gastropoda).

Toxic effects of the cylindrospermopsin and chlorpyrifos combination on the differentiated SH-SY5Y human neuroblastoma cell line.

BPA/Phenols

Postnatal exposure to Bisphenol S induces liver injury in mice: Possible implication of PPARγ receptor.

High-content analysis of testicular toxicity of BPA and its selected analogs in mouse spermatogonial, Sertoli cells, and Leydig cells revealed BPAF induced unique multinucleation phenotype associated with the increased DNA synthesis.

Cuscuta chinensis flavonoids reducing oxidative stress of the improve sperm damage in bisphenol A exposed mice offspring.

Low-dose BPA and its substitute BPS promote ovarian cancer cell stemness via a non-canonical PINK1/p53 mitophagic signaling.

Phthalates

Role of ROS/JAK2/STAT3 signaling pathway in di-n-butyl phthalate-induced testosterone synthesis inhibition and antagonism of lycopene.

In-depth profiling of di(2-ethylhexyl) phthalate metabolic footprints in rats using click chemistry-mass spectrometry probes.

Mitocytosis Is Critical for Phthalate-Induced Injury to the Ovarian Granulosa Cell Layer in Quail (Coturnix japonica).

Effects of phthalates on marine organisms: cytotoxicity and genotoxicity of mono-(2-ethylhexyl)-phthalate (MEHP) on European sea bass (Dicentrarchus labrax) embryonic cell line.

Di-(2-ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation by activating Notch signaling pathway.

Perfluoroalkyl Substances

Effects of PFOS, F53-B and F53-B on locomotor behaviour, the dopamine system and mitochondrial function in developing zebrafish (Danio rerio).

PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics.

Transcriptomic effects of Perfluoralkyl acids on the adipose tissue of a songbird species at environmentally relevant concentrations.

Gut Microbiome-Host Metabolome Homeostasis upon Exposure to PFOS and GenX in Male Mice.

Assessment of Mouse Liver Histopathology Following Exposure to HFPO-DA With Emphasis on Understanding Mechanisms of Hepatocellular Death.

Perfluorooctane sulfonate-induced apoptosis in kidney cells by triggering the NOX4/ROS/JNK axis and antagonism of cannabidiol.

Flame Retardants

Spleen Toxicity of Organophosphorus Flame Retardant TDCPP in Mice and the Related Mechanisms.

Organotins

Marine Pollutant Tributyltin Affects DNA Methylation and Fitness of Banded Murex (Hexaplex trunculus) Populations.

Evaluating the histomorphological and biochemical changes induced by Tributyltin Chloride on pituitary-testicular axis of adult albino rats and the possible ameliorative role of hesperidin.

The effect of acute toxicity from tributyltin on Liza haematocheila liver: Energy metabolic disturbance, oxidative stress, and apoptosis.

Pesticides

Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish.

Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro-in vivo extrapolation.

Heatwaves, elevated temperatures, and a pesticide cause interactive effects on multi-trophic levels of a freshwater ecosystem.

The combined effects of atrazine and warming on environmental adaptability in lizards (Eremias argus) from the perspective of a life-history traits trade-off: Gender differences in trade-off strategies may reverse mortality risk.

Atrazine contaminated sites and bullfrog tadpoles: evasive trends and biochemical consequences.

The analysis of pesticides and fungicides in the inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase activity: mode of inhibition and mechanism.

Molecular and Biochemical Evidence of the Toxic Effects of Terbuthylazine and Malathion in Zebrafish.

Molecular and phenotypic effects of early exposure to an environmentally relevant pesticide mixture in the Pacific oyster, Crassostrea gigas.

Metals/Metalloids

Lactiplantibacillus plantarum P101 alleviated lead-induced more severe hepatic injury in obese mice, by promoting fecal lead excretion and enhancing antioxidative defense system.

Fluoride exposure disrupts the cytoskeletal arrangement and ATP synthesis of HT-22 cell by activating the RhoA/ROCK signaling pathway.

Baicalein alleviates arsenic-induced oxidative stress through activation of the Keap1/Nrf2 signalling pathway in normal human liver cells.

Joint effects of temperature and copper exposure on developmental and gene-expression responses of the marine copepod Tigriopus japonicus.

Effect of Interaction between Chromium(VI) with 17β-Estradiol and Its Metabolites on Breast Cancer Cell Lines MCF-7/WT and MDA-MB-175-VII: Preliminary Study.

Microplastics/Nanomaterials

Polystyrene microplastics promote liver inflammation by inducing the formation of macrophages extracellular traps.

Size-dependent effects of polystyrene microplastics on gut metagenome and antibiotic resistance in C57BL/6 mice.

Reproductive and metabolic toxic effects of polystyrene microplastics in adult female Wistar rats: a mechanistic study.

Increase in temperature increases ingestion and toxicity of polyamide microplastics in Nile tilapia.

Reproductive toxicity of microplastics in female mice and their offspring from induction of oxidative stress.

Polystyrene microplastic particles induced hepatotoxic injury via pyroptosis, oxidative stress, and fibrotic changes in adult male albino rats; the therapeutic role of silymarin.

Hemotoxic effects of polyethylene microplastics on mice.

The simultaneous administration of microplastics and cadmium alters rat testicular activity and changes the expression of PTMA, DAAM1 and PREP.

Biochemical, Genotoxic and Histological Implications of Polypropylene Microplastics on Freshwater Fish Oreochromis mossambicus: An Aquatic Eco-Toxicological Assessment.

Polystyrene Microplastics Induced Ovarian Toxicity in Juvenile Rats Associated with Oxidative Stress and Activation of the PERK-eIF2α-ATF4-CHOP Signaling Pathway.

Impact of Plastic-Related Compounds on P-Glycoprotein and Breast Cancer Resistance Protein In Vitro.

Polystyrene Microplastics of Varying Sizes and Shapes Induce Distinct Redox and Mitochondrial Stress Responses in a Caco-2 Monolayer.

Air Pollution

Multidimensional Analysis of Lung Lymph Nodes in a Mouse Model of Allergic Lung Inflammation following PM2.5 and Indeno[1,2,3-cd]pyrene Exposure. [see related Invited Perspective: Environmental Chemical-Sensing AHR Remains an Enigmatic Key Player in Toxicology.]

Pharmaceuticals/Personal Care Products

Cocktails of NSAIDs and 17α Ethinylestradiol at Environmentally Relevant Doses in Drinking Water Alter Puberty Onset in Mice Intergenerationally.

Miscellaneous

Cetyl Alcohol Polyethoxylates Disrupt Metabolic Health in Developmentally Exposed Zebrafish. [replacement chemicals for nonylphenols and others]

Crude oil exposure of early life stages of Atlantic haddock suggests threshold levels for developmental toxicity as low as 0.1 μg total polyaromatic hydrocarbon (TPAH)/L.

Comparative analysis of two new zebrafish models: the cyp1a low-expression line and cyp1a knockout line under PAHs exposure.

Biotransformation, metabolic response, and toxicity of UV-234 and UV-326 in larval zebrafish (Danio rerio).

Exposure/Environment Studies

Numerous Chemicals/Mixtures

PFAS, bisphenol, and paraben in Malaysian food and estimated dietary intake.

BPA/Phenols

Detection of bisphenol A in thermal paper receipts and assessment of human exposure: A case study from Sharjah, United Arab Emirates.

Phthalates

Exposure to Phthalates in European Children, Adolescents and Adults since 2005: A Harmonized Approach Based on Existing HBM Data in the HBM4EU Initiative.

Exposure to phthalates and DiNCH among preschool children in Sweden: Urinary metabolite concentrations and predictors of exposure.

Widespread distribution of phthalic acid esters in indoor and ambient air samples collected from Hanoi, Vietnam.

Occurrence of phthalates in different food matrices: A systematic review of the main sources of contamination and potential risks.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in blood samples from historically herbicide-sprayed areas and rural and industrialized unsprayed areas in Vietnam.

Prenatal exposure to 209 PCBs in mother-infant pairs from two cities in China: Levels, congener profiles, and transplacental transfer.

The effect of military conflict zone in the Middle East on atmospheric persistent organic pollutant contamination in its north.

The first full-congener analysis of 209 polychlorinated biphenyls (PCBs) in the blubber of short-finned pilot whales (Globicephala macrorhynchus) stranded along the coast of Savu Island, Indonesia.

Perfluoroalkyl Substances

Uptake of Per- and Polyfluoroalkyl Substances by Fish, Mussel, and Passive Samplers in Mobile-Laboratory Exposures Using Groundwater from a Contamination Plume at a Historical Fire Training Area, Cape Cod, Massachusetts.

PFAS in fish from AFFF-impacted environments: Analytical method development and field application at a Canadian international civilian airport.

Improved total organic fluorine methods for more comprehensive measurement of PFAS in industrial wastewater, river water, and air.

Complete defluorination of perfluorooctanoic acid (PFOA) by ultrasonic pyrolysis towards zero fluoro-pollution.

Longer-term temporal trends in PFAS concentrations in Midwestern landfill leachate.

Electronic-waste-associated pollution of per- and polyfluoroalkyl substances: Environmental occurrence and human exposure.

PFAS Contamination: Pathway from Communication to Behavioral Outcomes.

Perfluoroalkyl substances (PFASs) in aquatic products from the Yellow-Bohai Sea coasts, China: Concentrations and profiles across species and regions.

Pesticides

Occurrence, distribution and potential risk to infants of neonicotinoids in breast milk: A case study in Hangzhou, China.

Metals/Metalloids

National-Scale Assessment of Environmental Justice Trends in Public School Proximity to Industrial Lead Sources.

Microplastics/Nanomaterials

Accumulation and re-distribution of microplastics via aquatic plants and macroalgae – A review of field studies.

Current levels of microplastic pollution impact wild seabird gut microbiomes.

Air Pollution

Breaking New Ground: Space Agencies and Epidemiologists Partner Up on Particulates.

Pharmaceuticals/Personal Care Products

Potential Carcinogens in Makeup Cosmetics.

Miscellaneous

Occupational Exposure and Health Impact Assessment of Diisocyanates in Finland.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me and ask to join the EDC Science Weekly group EDC_research@googlegroups.com. The searchable archives are at https://groups.google.com/d/forum/edc_research or online at https://heeds.org/category/edc-science-weekly/. Compiled by Sarah Howard of Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

If you enjoy this newsletter, please feel free to donate here! Thank you!

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.