EDC Science Weekly, Feb. 14-27, 2025

Post author:HEEDS
Post published:February 27, 2025
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed the past two weeks.

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries, Reviews/Meta-Analyses, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Highlights:

Independent Science Key to Breaking Stalemates in Global Plastics Treaty Negotiations

Microplastics everywhere: in intestinal tissue of Crohn’s disease patients, in human ovarian follicular fluid, in human skeletal tissues, with major adverse cardiac events in patients with myocardial infarction and due to cardiopulmonary bypass in children. Along with chemical exposures in neonatal, pediatric, and cardiac intensive care units.

Science summaries and highlights

Events

Feb. 27 webinar (today!): Plastics, Chemicals & Cancer: The role of the Global Plastics Treaty in preventing breast cancer [CHE Alaska]

Mar. 4 webinar: GMO Corn & Glyphosate: New evidence for precaution from Mexican scientists [CHE]

Mar. 11 Grand Rounds: Childhood Cancer and the Environment: Prevention to Survivorship Objectives [Boston Children’s Hospital and New England PEHSU]

Mar. 11 webinar: Reducing single use plastics [National Academy of Medicine]

Mar. 14-15: Lou Guillette Jr. Symposium, in person at the University of Florida in Gainesville AND via zoom, details to come! [HEEDS]

Mar. 26 webinar: Impacts of Fracking in North & South America: Resources in English & Spanish [CHE]

Apr. 15-16: Iowa PFAS Conference, in person in Iowa City [Iowa College of Engineering]

Apr. 25: HEEDS EDC-North Carolina group 5th Annual Meeting, in person in Raleigh [HEEDS]

Apr. 27-29 conference: Break the Cycle of Children’s Environmental Health Disparities

June 16-17 workshop: Roadmap to phase out animal testing for chemical safety assessments [ECHA]

July 30 – Aug. 1 conference: U.S. DOHaD Society Annual Meeting.

More events

Regulations/Policy

Mapping commercial practices of the pesticide industry to shape science and policymaking: a scoping review.

New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use.

More EDC policy and regulations open for comment and links to preserved resources removed from U.S. federal websites

Methods/Tools/Screening

GRADE guidance 40: The GRADE evidence-to-decision framework for environmental and occupational health.

Use of alternatives to animal testing for Environmental Safety Assessment (ESA): Report from the 2023 EPAA partners’ forum

Integration of New Approach Methods for the Assessment of Data Poor Chemicals.

AOP-networkFinder-a versatile tool for the reconstruction and visualization of Adverse Outcome Pathway networks from AOP-Wiki.

Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology.

Intra-laboratory validation of yeast-based reporter gene assays for human thyroid hormone receptors.

Screening of Estrogen Receptor Activity of Per- and Polyfluoroalkyl Substances Based on Deep Learning and In Vivo Assessment.

Commentaries

Independent Science Key to Breaking Stalemates in Global Plastics Treaty Negotiations

Editorial: Thyroid endocrine disruptors. [intro to a research topic in Frontiers in Endocrinology]

Editorial: Endocrine disruptors in molecular and structural endocrinology. [intro to a research topic in Frontiers in Endocrinology]

Reviews/Meta-Analyses

Numerous Chemicals/Mixtures

Equity in Early Life: Advancing Environmental Justice for Maternal and Child Health.

Exposed and Vulnerable: Sources and Health Implications of Chemical Exposures in Neonatal, Pediatric, and Cardiac Intensive Care Units.

Prenatal and Perinatal Factors Associated with Infant Acute Lymphoblastic Leukaemia: A Scoping Review.

The Role of Genetic, Environmental, and Dietary Factors in Alzheimer’s Disease: A Narrative Review.

Chemical safety and risk assessment of bio-based and/or biodegradable polymers for food contact: A review.

Research status of anti-obesogenic functional foods: mechanism of endocrine-disrupting chemicals and glucocorticoid receptor pathway.

Rubber Crumb Infill in Synthetic Turf and Health Outcomes: A Review of the Literature on Polycyclic Aromatic Hydrocarbons and Metalloids.

EGFR in Placental Health and Disease: Pathways, Dysfunction, and Chemical Disruption.

Meta-Analysis of Endocrine-Disrupting Chemical Effects on Earthworm Functional Traits.

BPA/Phenols

The Biological Effects of Bisphenol AF in Reproduction and Development: What Do We Know So Far?

Uterine Microbiota and Bisphenols: Novel Influencers in Reproductive Health.

Phthalates

Association between phthalate exposure and metabolic dysfunction-associated steatotic liver disease (MASLD) – systematic literature review.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Dioxins do not only bind to AHR but also team up with EGFR at the cell-surface: a novel mode of action of toxicological relevance?

Uncovering the Potential Link Between Polychlorinated Biphenyls and Cardiovascular Diseases: A Comprehensive Analysis.

Polyhalogenated carbazoles in the environment: Analysis, origins, occurrence, and toxicity.

PFAS

A Review of the Occurrence and Distribution of Per- and Polyfluoroalkyl Substances (PFAS) in Human Organs and Fetal Tissues.

PFC/PFAS concentrations in human milk and infant exposure through lactation: a comprehensive review of the scientific literature.

Poly- and per-fluoroalkyl substances toxicity on skeletal and cognitive well-being: a comprehensive review.

A systematic review of methods for the analysis of total per- and polyfluoroalkyl substances (PFAS).

Ecotoxicological effects of per- and polyfluoroalkyl substances in aquatic organisms: A review.

Non-Invasive Matrices for the Human Biomonitoring of PFAS: An Updated Review of the Scientific Literature.

Pesticides

Pesticides have negative effects on non-target organisms.

Triazoles in the environment: An update on occurrence, fate, health hazards, and removal techniques.

DNA methylation in the association between pesticide exposures and type 2 diabetes.

Metals/Metalloids

Effects of Trace Elements on Endocrine Function and Pathogenesis of Thyroid Diseases-A Literature Review.

Association between toxic heavy metals and noncancerous thyroid disease: a scoping review.

Mercury exposure and childhood outcomes: an overview of systematic reviews.

Exposure to arsenic and cognitive impairment in children: A systematic review.

Microplastics/Nanomaterials

Microplastics in our diet: A growing concern for human health.

Microplastic effects on mouse colon in normal and colitis conditions: A literature review.

How aging microplastics influence heavy metal environmental fate and bioavailability: A systematic review.

The Risk from widespread Micro- and Nano-Plastic Contamination on a Global Scale and the Threat to Children’s Health.

Micro- and nano-plastics pollution in the marine environment: Progresses, drawbacks and future guidelines.

Miscellaneous

Ultra-Processed Foods and Type 2 Diabetes Mellitus: What Is the Evidence So Far? [includes BPA etc.]

Human Health Studies

Numerous Chemicals/Mixtures

Neurobehavioral effects of gestational exposure to mixtures of non-persistent endocrine disruptors in preschool-aged children: the Environmental influences on Child Health Outcomes (ECHO) Program.

White matter microstructural integrity mediates associations between prenatal endocrine-disrupting chemicals exposure and intelligence in adolescents. [PFAS and phthalates]

Exploring the Joint Association Between Agrichemical Mixtures and Pediatric Cancer.

Exploring the association between exposure to pesticides, polycyclic aromatic hydrocarbons, and phthalates and metabolic syndrome in National Health and Nutrition Examination Survey in the USA, 2007-2012: utilizing a multi-step statistical strategy.

Environmental Chemical-Induced Cardiometabolic Disorders: Combined Epidemiological and Experimental Evidence. [PFAS etc.]

Alterations of early-life gut microbiome in hospitalized infants with chemical pollutants exposure.

Early-life exposure to mixtures of Endocrine-Disrupting Chemicals and a Multi-domain Health Score in preschool children.

Co-exposure to multiple endocrine-disrupting chemicals and oxidative stress: Epidemiological evidence of nonmonotonic dose response curves.

Unveiling the effect of urinary xenoestrogens on chronic kidney disease in adults: A machine learning model.

Access to Interpretable Data to Support Disproportionate Health Risks from Industrial Releases: A Case Study on the Environmental Protection Agency’s Datasets and Their Application to the Latinx Communities of Houston, Texas

BPA

Association between bisphenol A exposure and adiposity measures in children.

Phthalates

Phthalate exposure profiles during baby delivery and their association with reproductive hormone changes and newborn outcomes.

Urinary concentrations of phthalate metabolites and the survival of high-grade serous ovarian cancer with advanced stage.

Parabens/Triclosan/Antimicrobials

Association of environmental phenol and paraben exposure with allergic biomarkers in eczema: findings from NHANES 2005-2006.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Metabolic Signatures in Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures to Blood Pressure Five Years After Bariatric Surgery Among Adolescents.

A novel approach to the relation of multi-pollutant effect and kidney dysfunction: data analysis from the Korean National Environmental Health Survey Cycle 3 (2015-2017).

Associations between blood levels of persistent organic pollutants and oxidative stress biomarkers among women in France in the 90’s.

Persistent organic pollutants and plasma microRNAs: A community-based profiling analysis.

Epigenetics-Based Age Acceleration Associated with 2,3,7,8 TCDD Exposure in Older Americans.

PFAS

Perfluoroalkyl substances and preterm birth.

Maternal per- and polyfluoroalkyl substance concentrations and placental DNA methylation of thyroid hormone-related genes.

PFAS exposure during pregnancy: Implications for placental health and functioning.

Exposure to per- and polyfluoroalkyl substances in residential settled dust and risk of childhood acute lymphoblastic leukemia.

Effects of Serum Insulin and Insulin-Like Growth Factor 1 Levels on the Association between Fetal Growth and Per- and Polyfluoroalkyl Substance Exposure Based on a Nested Case-Control Study.

Association between PFAS exposure and metabolic-related biomarkers in Spanish adolescents.

Concentrations of Serum Per- and Polyfluoroalkyl Substances and Lipid Health in Adolescents: A Cross-Sectional Study from the Korean National Environmental Health Survey 2018-2020.

Association between exposure to per- and polyfluoroalkyl substances (PFAS) and chronic cough in American adults: Results from NHANES 2003-2012.

Association of perfluoroalkyl substance (PFAS) on vitamin D biomarkers in a highly exposed population of the Veneto Region in Italy.

Flame Retardants

Effects of organophosphate esters on thyroid function during pregnancy: Risk of endocrine disruptors during early- and mid-pregnancy.

Identification of the associations between co-exposure to organophosphate flame retardants and thyroid dysfunction and exposure risk factors in residents of Shanghai, China.

Pesticides

Environmental exposure to pesticides is associated with oxidative stress, oxidative DNA damage, and elevated interleukin-8 in a child population.

Application of Simazine, Atrazine, and Lindane Pesticides Are Associated with Incident Parkinson’s Disease Risk in the Rocky Mountain Region

Effects of neonicotinoid pesticide exposure in the first trimester on gestational diabetes mellitus based on interpretable machine learning.

Comprehensive Cross-Sectional Study of the Triglyceride Glucose Index, Organophosphate Pesticide Exposure, and Cardiovascular Diseases: A Machine Learning Integrated Approach.

Metals/Metalloids

Association between urinary heavy metal/trace element concentrations and kidney function: a prospective study.

Association between Heavy metals and triglyceride-glucose-related index: a mediation analysis of inflammation indicators.

Arsenic exposure and trend of incidence in urinary cancer from 1979 to 2019: A nationwide population-based study.

Evaluation of apoptotic proteins and genotoxic damage in arsenic exposure during childhood in a population in northern Mexico.

Exposure to inorganic arsenic and hypertension among non-diabetic Mexican women.

Combined Effects of Arsenic, Cadmium, and Mercury with Cardiovascular Disease Risk: Insights from the All of Us Research Program

Microplastics/Nanomaterials

Microplastics and nanoplastics increase major adverse cardiac events in patients with myocardial infarction.

Microplastics Accumulation in Fibrotic Intestinal Tissue of Crohn’s Disease Patients.

First evidence of microplastics in human ovarian follicular fluid: An emerging threat to female fertility.

Microplastics in human skeletal tissues: Presence, distribution and health implications.

Laboratory Studies

Numerous Chemicals/Mixtures

Co-exposure to enrofloxacin and atrazine enhances the hepatotoxicity in Larimichthys crocea by targeting the hypothalamic-pituitary-thyroid and gut-liver axes.

BPA/Phenols

Embryonic BPF exposure induces neurodevelopmental and neurobehavioral toxicity by affecting neural stem cell proliferation in Drosophila.

Intake of Trans-Fat Diet With Prenatal Bisphenol A Exposure Induce Global DNA Methylation in Rats Offspring.

Low-dose bisphenol AF exerts slight effects on glycolipid metabolism but causes metabolic disorders under the stress of Western diet in mice.

Anti-obesogenic effect of standardized Brassica juncea extract on bisphenol A-induced 3T3-L1 preadipocytes and C57BL/6J obese mice.

Bisphenol S interrupted axonogenesis on a human embryonic stem cells derived neural differentiation model: Conserved axon guidance and WNT signaling pathway involved.

Ancestral bisphenol A exposure led to non-alcoholic fatty liver disease and sex-specific alterations in proline and bile metabolism pathways in the liver .

Bisphenol A exposure alters hormonal modulation and responsivity in the prostate of aged female gerbils.

Sub-network transcriptome dataset for diseases associated with exposure to bisphenol F and bisphenol S in human SH-SY5Y neuroblastoma cells.

Effects of multiple novel bisphenol S analogs on adipogenesis in 3T3-L1 cells.

The Mechanism of Bisphenol S-Induced Atherosclerosis Elucidated Based on Network Toxicology, Molecular Docking, and Machine Learning.

Exposure to bisphenol S induces organ toxicity by disrupting oxidative and antioxidant defense system and blood physiology in Labeo rohita (Hamilton, 1822).

BHPF inhibits early embryonic development in mice by disrupting maternal-to-zygotic transition and mitochondrial function.

Nonylphenol

Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats.

Phthalates

Prenatal exposure to an environmentally relevant phthalate mixture alters oxidative stress, apoptosis, cell cycle regulators, and steroidogenic factors in the ovaries of F1 mice.

Prenatal DEHP exposure induces hippocampal neurotoxicity in male offspring via PTEN dysregulation and impaired Akt/mTOR and NMDA signaling.

Phthalates in face masks and their effects on cellular energetics in human bronchial epithelial cells.

Short-term subacute di(2-ethylhexyl) phthalate exposure disrupts gut microbiota, metabolome, liver transcriptome, immunity, and induces liver injury in rats.

Parabens/Triclosan/Antimicrobials

Impact of paraben on uterine collagen: An integrated and targeted Correlative approach using second harmonic generation microscopy, nanoindentation, and atomic force microscopy.

Multigenerational immunotoxicity assessment: A three-generation study in Drosophila melanogaster upon developmental exposure to triclosan.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Unveiling the transcriptional pattern of Epithelial ovarian carcinoma-related microRNAs-mRNAs network after mouse exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin.

PFAS

Single-cell RNA sequencing reveals tissue-specific transcriptomic changes induced by perfluorooctanesulfonic acid (PFOS) in larval zebrafish (Danio rerio).

A group of novel polyfluoroether substances affects lipid metabolism in human hepatocyte HepaRG cells less than classic perfluoroalkyl compounds.

Identifying prognostic biomarkers and immune interactions in ovarian cancer associated with perfluorooctanoic acid exposure: Insights from comparative toxicogenomics and molecular docking studies.

6:2 fluorotelomer sulfonate as a safer alternative to PFOS: Comparative cytotoxicity and oxidative stress mechanisms in pancreatic β-cells (INS-1 model).

Perfluorobutanesulfonate Induces Hypothalamic-Pituitary-Gonadal Axis Disruption and Gonadal Dysplasia of Lithobates catesbeianus Tadpoles.

Neurotoxic effects of per- and polyfluoroalkyl substances (PFAS) mixture exposure in mice: Accumulations in brain and associated changes of behaviors, metabolome, and transcriptome.

Neurotoxic effects of chronic exposure to perfluorobutane sulfonate in adult zebrafish (Danio Rerio).

Protective Effects of Resveratrol Against Perfluorooctanoic Acid-Induced Testicular and Epididymal Toxicity in Adult Rats Exposed During Their Prepubertal Period.

Utilization of Artificial Intelligence Coupled with a High-Throughput, High-Content Platform in the Exploration of Neurodevelopmental Toxicity of Individual and Combined PFAS.

Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice.

Hepatotoxicity in Carp (Carassius auratus) Exposed to Perfluorooctane Sulfonate (PFOS): Integrative Histopathology and Transcriptomics Analysis

Flame Retardants

Interaction between Tetrabromobisphenol A and invertebrates in rigid polyurethane biodegradation: Inhibitory effects, chemical transformation and microbial adaptation.

Chronic Exposure to Environmental Concentrations of Tetrabromobisphenol A Disrupts Insulin and Lipid Homeostasis in Diet-Induced Obese Mice.

Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.

Organotins

Multi-omics analysis reveals the toxic mechanism of tributyltin exposure causing digestive gland oxidative stress in cuttlefish (Sepia pharaonis).

Pesticides

Ameliorating Paraquat-Induced Nephrotoxicity in Rats: Protective Effects of Nanocurcumin on Renal Histology and Molecular Pathways.

A network toxicology and molecular docking-based approach revealed shared hepatotoxic mechanisms and targets between the herbicide 2,4-D and its metabolite 2,4-DCP.

Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain.

The Effect of Chrysin Nanocrystal on the Thyroid Gland of Rats Exposed to Chlorpyrifos.

Gene × environment interaction between heterozygous deletion of the ADHD risk gene latrophilin-3 (adgrl3) and developmental deltamethrin exposure in Sprague Dawley rats.

Effect of the neonicotinoid pesticide clothianidin at a no-observed-adverse-effect-level (NOAEL) dose on maternal behavior in pregnant mice and their female offspring.

Metals/Metalloids

Gut Dysbiosis Exacerbates Intestinal Absorption of Cadmium and Arsenic from Cocontaminated Rice in Mice Due to Impaired Intestinal Barrier Functions.

Exacerbation of polyethylene microplastics in animal models of DSS-induced colitis through damage to intestinal epithelial cell conjunctions.

Microplastics/Nanomaterials

Adolescent exposure to micro/nanoplastics induces cognitive impairments in mice with neuronal morphological damage and multi-omic alterations.

Fate of polystyrene micro- and nanoplastics in zebrafish liver cells: Influence of protein corona on transport, oxidative stress, and glycolipid metabolism.

Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.

Mixtures of polystyrene micro and nanoplastics affects fat and glucose metabolism in 3T3-L1 adipocytes and zebrafish larvae.

Baicalein inhibited amino-modified polystyrene nanoplastics induced human umbilical vein endothelial cells pyroptosis by reducing the expression of NLRP3/Caspase-1/GSDMD pathway.

Polystyrene Microplastics Trigger Colonic Inflammation in Rats via the TLR4/NF-κB/COX-2 Pathway and Modulation of Intestinal Microbiota.

Lactobacillus plantarum reduces polystyrene microplastic induced toxicity via multiple pathways: A potentially effective and safe dietary strategy to counteract microplastic harm.

Short-term PS-NP exposure in early adulthood induces neuronal damage in middle-aged mice via microglia-mediated neuroinflammation.

Exposure to polyethylene and polyvinylchloride microplastics caused advanced puberty onset in females through promoting hypothalamic GnRH expression.

Combined toxicity of polystyrene microplastics and perfluorobutane sulfonate on mouse liver: Impact on lipid metabolism and gut-liver axis disruption.

Exposure to Polystyrene Nanoplastics Compromise Ovarian Reserve Function and Endometrial Decidualization in Early Pregnant Mice.

Pharmaceuticals/Personal Care Products

Exploring the mechanism of PPCPs on human metabolic diseases based on network toxicology and molecular docking.

Tire Wear Particles

Molecular insight on conformational alterations and functional changes of acetylcholinesterase induced by an emerging environmental pollutant 6PPD-quinone.

6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: in vitro and in silico approaches.

Low-dose tire wear chemical 6PPD-Q exposure elicit fatty liver via promoting fatty acid biosynthesis in ICR mice.

6PPD impairs growth performance by inducing intestinal oxidative stress and ferroptosis in zebrafish.

Mass Spectrometry Imaging Unveils the Metabolic Effect of 6PPD-Quinone in Exposed Mice.

Exposure/Environment Studies

Numerous Chemicals/Mixtures

Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort.

Serum concentrations of persistent endocrine-disrupting chemicals in U.S. military personnel: A comparison by race/ethnicity and sex.

Detection and risk assessment of bisphenol-A and phthalate esters in bottled water: implications for public health.

Formation and aqueous phase leaching of organic compounds following thermal degradation of commercial drinking water plastic pipes.

Early life development and sex determination of brown trout affected by treated wastewater discharge.

The Common Kestrel as an Environmental Bioindicator of Toxic Chemicals on Tenerife Island (Canary Islands, Spain).

Using Intervention Mapping and Behavior Change Techniques to Develop a Health Promotion Intervention on Endocrine Disruptors: Development Study

Phthalates

Filling gaps in population estimates of phthalate exposure globally: A systematic review and meta-analysis of international biomonitoring data.

Parabens/Triclosan/Antimicrobials

Young infants’ exposure to parabens: lotion use as a potential source of exposure.

Effects of dietary sources and personal care products on paraben exposure in young Korean adults: A crossover intervention study.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Housing characteristics, dietary patterns, and sociodemographic characteristics as predictors of persistent organic pollutant exposure among African American pregnant women in Atlanta.

PFAS

Serum concentrations of PFAS across Australian States and Territories.

Quantification of PFAS in soils treated with biosolids in ten northeastern US farms.

Accumulation and trophic transfer of per- and polyfluoroalkyl substances (PFAS) in estuarine organisms determined via stable isotopes.

Per- and polyfluoroalkyl substances in untreated and treated sludge/biosolids from 27 water resource recovery facilities across the United States and Canada.

Broad-spectrum capture of hundreds of per- and polyfluoroalkyl substances from fluorochemical wastewater.

A High Efficiency Method for the Extraction and Quantitative Analysis of 45 PFAS in Whole Fish.

Exploring per- and polyfluoroalkyl substance distribution in Arctic wastewater treatment lagoons and natural wetlands: First record in Nunavik, Canada.

Whale baleen to monitor per- and polyfluoroalkyl substances (PFAS) in marine environments.

Perfluoroalkyl Acids (PFAAs) and their precursors in sediments and adjacent riparian soils from the Three Gorges Reservoir, China: Contamination characteristics, source apportionment and ecological risks.

Flame Retardants

National urinary metabolites of organophosphate flame retardants in urban Chinese residents.

Pesticides

Temporal trends of 46 pesticides and 8 transformation products in surface and drinking water in Québec, Canada (2021-2023): Potential higher health risks of transformation products than parent pesticides.

Metals/Metalloids

Mercury concentrations in historic autopsies from Grassy Narrows First Nation.

Microplastics/Nanomaterials

Nanoplastics in the human brain and their change in abundance over time.

Micronanoplastic exposure due to cardiopulmonary bypass in children: A prospective observational study.

Unveiling the deep-sea microplastic Odyssey: Characteristics, distribution, and ecological implications in Pacific Ocean sediments.

Air Pollution

Notes from the Field: Elevated Atmospheric Lead Levels During the Los Angeles Urban Fires – California, January 2025.

Pharmaceuticals/Personal Care Products

Evaluating personal care product use by Environmental Working Group hazard scores in relation to consumers’ sociodemographic characteristics, purchasing behaviors, and product safety perceptions.

Validating the Black Identity, Hair Product Use, and Breast Cancer Scale (BHBS) Among Black Breast Cancer Survivors

Miscellaneous

Machine learning-enhanced surface-enhanced spectroscopic detection of polycyclic aromatic hydrocarbons in the human placenta

Projecting airborne tire wear particle emissions in the United States in the era of electric vehicles.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Industry-funded articles are included without notation. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me and ask to join the EDC Science Weekly group EDC_research@googlegroups.com. There are searchable archives. Compiled by Sarah Howard of Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

If you enjoy this newsletter, please feel free to donate here! Thank you!

EHN EHN

Lou Guillette Jr. Memorial Symposium
by Sarah Howard on February 14, 2025 at 3:36 pm
The agenda is now available for the March 14-15 Lou Guillette Jr. Memorial Symposium, hosted by HEEDS, at the University of Florida and online via Zoom. It will celebrate the life and legacy of Dr. Guillette, gather together his trainees and colleagues, and focus on the endocrine disruption research that Lou made famous. Information and agenda here.
North Carolina EDC working group 5th annual meeting
by Sarah Howard on February 13, 2025 at 12:46 pm
On Friday, April 25, 2025, Healthy Environment and Endocrine Disruptor Strategies (HEEDS) is hosting the 5th Annual Meeting of EDC-NC, its North Carolina working group on endocrine disrupting chemicals (EDCs). Attendance is open to anyone and the cost is free. More information.
Webinar: Impacts of fracking in North and South America (in English and Spanish)
by Sarah Howard on February 11, 2025 at 4:04 pm
This March 26 webinar will be presented with simultaneous English/Spanish interpretation. It will discuss the 9th edition of the Compendium of Scientific, Medical, and Media Findings Demonstrating Risks and Harms of Fracking and Associated Gas and Oil Infrastructure, published in 2023 by Concerned Health Professionals of New York and Physicians for Social Responsibility. The webinar is hosted by the Collaborative on Health and Environment (CHE).

EHN EHN

Plastic water pipes leach dangerous chemicals when damaged in wildfires
by Katherine McMahon,Sarah Howard on March 7, 2025 at 10:18 pm
A new study published in Journal of Hazardous Materials demonstrates how plastic drinking water pipes break down when subjected to high temperatures. “Various VOCs, such as benzene… and vinyl chloride, have been detected in drinking water systems exceeding their health-based state and federal maximum contaminant levels.”
Standing up for science: Around the world, scientists protest Trump threats to their work
by EHN Curators on March 7, 2025 at 12:51 pm
Thousands of scientists worldwide are uniting against the Trump administration’s attacks on science, with major protests planned today to defend research funding, diversity initiatives, and academic freedom. Bob Berwyn reports for Inside Climate News.
Pesticide mixtures linked to higher rates of childhood cancer, study finds
by EHN Curators on March 7, 2025 at 11:04 am
Exposure to multiple pesticides significantly increases the risk of childhood cancers, with new research showing higher rates of brain cancer and leukemia in agricultural communities. Tom Perkins reports for The Guardian.

EHN EHN

Trump’s EPA moves to roll back chemical safety rules
by EHN Curators on March 7, 2025 at 12:52 pm
The Trump administration is pulling back on Biden-era rules that required chemical facilities to adopt stronger safety measures against disasters. Hiroko Tabuchi reports for The New York Times.
Canada moves to regulate PFAS as toxic chemicals
by EHN Curators on March 7, 2025 at 11:40 am
The Canadian government is adding per- and polyfluoroalkyl substances (PFAS) to its list of toxic substances, a move that could lead to restrictions on the chemicals, which have been linked to cancer and other health risks. Inayat Singh reports for CBC.
Tennessee bill could limit state regulation of PFAS and other chemicals
by EHN Curators on March 7, 2025 at 10:56 am
A proposed Tennessee bill would restrict state agencies from enacting regulations on hazardous chemicals, including PFAS, unless lawmakers prove the rules are based on “sound science.” Cassandra Stephenson reports for Tennessee Lookout.