EDC Science Weekly, Dec. 23, 2020 – Jan. 5, 2021

Post author:HEEDS
Post published:January 5, 2021
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed over the past two weeks (and thus twice as long as usual!).

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries/News Items, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Webinar Jan 13: An introduction to the “essential use” concept and its application to PFAS

Online conference June 15-17: 1st International Endocrine Disruptor Conference on the Island of Ireland

Regulations/Policy

An evaluation of health-based federal and state PFOA drinking water guidelines in the United States

Methods/Tools/Screening

Knowledge Organization Systems for Systematic Chemical Assessments.

Community Approaches for Integrating Environmental Exposures into Human Models of Disease.

Incorporating Lines of Evidence from New Approach Methodologies (NAMs) to Reduce Uncertainties in a Category Based Read-Across: A Case Study for Repeated Dose Toxicity.

Towards a systematic use of effect biomarkers in population and occupational biomonitoring.

Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models.

Structure-activity relationship-based chemical classification of highly imbalanced Tox21 datasets.

Impact of environmental neurotoxic: current methods and usefulness of human stem cells.

Prediction of aquatic toxicity of chemical mixtures by the QSAR approach using 2D structural descriptors.

Proposal for a neurotoxic classification for chemicals at work.

Commentaries/News Items

Knowledge gaps and research needs on microplastics. [Editorial]

A growing drive to get rid of cancer-linked “forever chemicals”: As concern mounts over the health effects of a huge and ubiquitous family of persistent organic compounds, researchers are making headway on remediation strategies despite uncertainties over costs and regulations.

Linking Environmental Science with Geochemistry.

Reviews

Numerous EDCs

Praegnatio Perturbatio – Impact of Endocrine Disrupting Chemicals.

Endocrine disrupting chemicals and metabolic disorders in the liver: What if we also looked at the female side?

Endocrine disrupting chemicals: impacts on human fertility and fecundity during the peri-conception period.

Multisystemic alterations in humans induced by bisphenol A and phthalates: Experimental, epidemiological and clinical studies reveal the need to change health policies.

An integrative toxicogenomic analysis of plastic additives.

Human Health and Ocean Pollution.

Effects of endocrine disrupting chemicals on myelin development and diseases.

Developmental programming of the female reproductive system-a review.

Paternal metabolic and cardiovascular programming of their offspring: A systematic scoping review.

Environmental pollutants exposure: A potential contributor for aging and age-related diseases.

Environmental exposures and the etiopathogenesis of Alzheimer’s disease: The potential role of BACE1 as a critical neurotoxic target.

BPA/Phenols

A targeted review on fate, occurrence, risk and health implications of bisphenol analogues.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

The Aryl Hydrocarbon Receptor in Energy Balance: The Road from Dioxin-Induced Wasting Syndrome to Combating Obesity with Ahr Ligands.

The Role of Epidemiology Studies in Human Health Risk Assessment of Polychlorinated Biphenyls.

Perfluoroalkyl Substances

Assessing the human health risks of per- and polyfluoroalkyl substances: A need for greater focus on their interactions as mixtures.

PFAS and cancer, a scoping review of the epidemiologic evidence.

Pesticides

Glyphosate: How do ongoing controversies, market characteristics, and funding influence the global research landscape?

Organopesticides and fertility: where does the link lead to?

Environmental Health Threats to Latino Migrant Farmworkers.

Potentially Toxic Elements

Zinc and Cadmium in the Aetiology and Pathogenesis of Osteoarthritis and Rheumatoid Arthritis.

Microplastics/Nanoplastics

Microplastic Contamination of Seafood Intended for Human Consumption: A Systematic Review and Meta-Analysis.

Mangroves as unique but understudied traps for anthropogenic marine debris: A review of present information and the way forward.

Microplastics Pollution as an Invisible Potential Threat to Food Safety and Security, Policy Challenges and the Way Forward.

Reviewing nanoplastic toxicology: It’s an interface problem.

Air Pollution

Acute effect of ambient fine particulate matter on heart rate variability: an updated systematic review and meta-analysis of panel studies.

The Role of Traffic-Related Air Pollution on Neurodegenerative Diseases in Older People: An Epidemiological Perspective.

Air pollution and pre-eclampsia; associations and potential mechanisms.

Long-Term PM_2.5 Exposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta-Analysis.

Airway hyperresponsiveness development and the toxicity of PM2.5.

Air Pollution and Central Nervous System Disease: A Review of the Impact of Fine Particulate Matter on Neurological Disorders.

Pharmaceuticals/Personal Care Products

Possible Adverse Effects of Food Additive E171 (Titanium Dioxide) Related to Particle Specific Human Toxicity, Including the Immune System.

Miscellaneous

Gut microbiota of animals living in polluted environments are a potential resource of anticancer molecules.

Progression of potential etiologies of the chronic kidney disease of unknown etiology in Sri Lanka

The impact of xenoestrogens on effectiveness of treatment for hormone-dependent breast cancer – current state of knowledge and perspectives for research

Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies.

Water quality prospective in Twenty First Century: Status of water quality in major river basins, contemporary strategies and impediments: A review.

Human Health Studies

Numerous Chemicals

Identifying windows of susceptibility to endocrine disrupting chemicals in relation to gestational weight gain among pregnant women attending a fertility clinic.

Association of exposure to polycyclic aromatic hydrocarbons and heavy metals with thyroid hormones in general adult population and potential mechanisms.

BPA/Phenols

Maternal environmental exposure to bisphenols and epigenome-wide DNA methylation in infant cord blood.

High fetal bisphenol A exposure enhances IL22 secretion: A proinflammatory cytokine.

Exposure to bisphenol A and breast cancer risk in northern Mexican women.

Phthalates

Incidence of uterine leiomyoma in relation to urinary concentrations of phthalate and phthalate alternative biomarkers: A prospective ultrasound study.

Phthalate levels in urine of pregnant women and their associated missed abortion risk.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Dioxin exposure associated with fecundability and infertility in mothers and daughters of Seveso, Italy.

Effects of organochlorine exposure on male reproductive disorders in an electronic waste area of South China.

High levels of organochlorine pesticides in drinking water as a risk factor for type 2 diabetes: A study in north India.

Perfluoroalkyl Substances

Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Umbilical Cord Blood DNA Methylation, and Cardio-Metabolic Indicators in Newborns: The Healthy Start Study.

The association between perfluoroalkyl substances and lipid profile in exposed pregnant women in the Veneto region, Italy.

Associations between perfluoroalkyl substances and thyroid hormones after high exposure through drinking water

Prenatal exposure to per- and polyfluoroalkyl substances in association with autism spectrum disorder in the MARBLES study.

Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort.

Flame Retardants

Exposure to organophosphate flame esters during early pregnancy and risk of spontaneous abortion: A case-control study.

Prenatal exposure to halogenated, aryl, and alkyl organophosphate esters and child neurodevelopment at two years of age.

Prenatal exposure to polybrominated diphenyl ethers (PBDEs) and cognitive ability in early childhood.

Pesticides

Occupational exposure to pesticides in female tea garden workers and adverse birth outcomes.

Potentially Toxic Elements

Prenatal exposure to mercury and precocious puberty: a prospective birth cohort study.

Association of lead, mercury, and cadmium with metabolic syndrome of young adults in South Korea: The Korea National Health and Nutrition Examination Survey (KNHANES) 2016.

Elevated lead levels in relation to low serum neuropeptide Y and adverse behavioral effects in preschool children with e-waste exposure.

Arsenic Exposure and Cancer-Related Proteins in Urine of Indigenous Bolivian Women.

Urinary trace elements in association with disease severity and outcome in patients with COVID-19.

Environmental doses of arsenic exposure are associated with increased reproductive-age male urinary hormone excretion and in vitro Leydig cell steroidogenesis.

Air Pollution

Maternal exposure to air pollution and umbilical asprosin concentration, a novel insulin-resistant marker.

The impact of particulate matter air pollution (PM2.5) on atherosclerosis in modernizing China: a report from the CATHAY study.

Associations between COVID-19 Incidence Rates and the Exposure to PM2.5 and NO₂: A Nationwide Observational Study in Italy.

Air Pollution Is Associated with COVID-19 Incidence and Mortality in Vienna, Austria.

Interaction between Long-Term Exposure to Fine Particulate Matter and Physical Activity, and Risk of Cardiovascular Disease and Overall Mortality in U.S. Women.

Long-term exposure to fine particulate matter and dementia incidence: A cohort study in Hong Kong.

Associations between changes in adipokines and exposure to fine and ultrafine particulate matter in ambient air in Beijing residents with and without pre-diabetes.

Polymorphisms in Oxidative Stress, Metabolic Detoxification, and Immune Function Genes, Maternal Exposure to Ambient Air Pollution, and Risk of Preterm Birth in Taiyuan, China.

Ambient air pollution exposure during the late gestational period is linked with lower placental iodine load in a Belgian birth cohort

Ambient Particle Components and Newborn Blood Pressure in Project Viva.

Is Environmental and Occupational Particulate Air Pollution Exposure Related to Type-2 Diabetes and Dementia? A Cross-Sectional Analysis of the UK Biobank.

Ambient particulate matter compositions and increased oxidative stress: Exposure-response analysis among high-level exposed population.

Ecological Study on Thyroid Cancer Incidence and Mortality in Association with European Union Member States’ Air Pollution.

Short-Term Exposure to Fine Particulate Matter and Hospitalizations for Acute Lower Respiratory Infection in Korean Children: A Time-Series Study in Seven Metropolitan Cities.

Air pollution and breast cancer risk in the Black Women’s Health Study.

Child buccal telomere length and mitochondrial DNA content as biomolecular markers of ageing in association with air pollution.

Association between airborne particulate matter and renal function: An analysis of 2.5 million young adults.

Dietary patterns and associations between air pollution and gestational diabetes mellitus.

Outdoor air pollution exposure and inter-relation of global cognitive performance and emotional distress in older women.

A National Difference in Differences Analysis of the Effect of PM_2.5 on Annual Death Rates.

Miscellaneous

Integrative Analysis of Gene-Specific DNA Methylation and Untargeted Metabolomics Data from the ELEMENT Cohort.

A Retrospective Chart Review Evaluating the Relationship between Cancer Diagnosis and Residential Water Source on the Lower Eastern Shore of Maryland, USA.

Laboratory Studies

BPA/Phenols

Bisphenol A promotes breast cancer cell proliferation by driving miR-381-3p-PTTG1-dependent cell cycle progression.

Bisphenol A promotes autophagy in ovarian granulosa cells by inducing AMPK/mTOR/ULK1 signalling pathway.

Mechanisms for the impacts of graphene oxide on the developmental toxicity and endocrine disruption induced by bisphenol A on zebrafish larvae.

Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S.

Bisphenol S perturbs Sertoli cell junctions in male rats via alterations in cytoskeletal organization mediated by an imbalance between mTORC1 and mTORC2

Isobaric tags for relative and absolute quantitation-based proteomics analysis of the effect of ginger oil on bisphenol A-induced breast cancer cell proliferation.

Multigenerational reproduction and developmental toxicity, and HPG axis gene expression study on environmentally-relevant concentrations of nonylphenol in zebrafish.

Phthalates

LncRNAs activate longevity regulation pathway due to aging of Leydig cells caused by DEHP exposure: A transcriptome-based study.

Short- and long-term effects of perinatal phthalate exposures on metabolic pathways in the mouse liver.

Aggravation of autism-like behavior in BTBR T+tf/J mice by environmental pollutant, di-(2-ethylhexyl) phthalate: Role of nuclear factor erythroid 2-related factor 2 and oxidative enzymes in innate immune cells and cerebellum.

Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line.

Parabens/Triclosan/Antimicrobials

Use of Parabens (Methyl and Butyl) during the Gestation Period: Mitochondrial Bioenergetics of the Testes and Antioxidant Capacity Alterations in Testes and Other Vital Organs of the F1 Generation.

Paraben exposure alters cell cycle progression and survival of spontaneously immortalized secretory murine oviductal epithelial (MOE) cells.

Exploring the multilevel effects of triclosan from development, reproduction to behavior using Drosophila melanogaster

ABC proteins activity and cytotoxicity in zebrafish hepatocytes exposed to triclosan.

Triclosan induces apoptosis in Burkitt lymphoma-derived BJAB cells through caspase and JNK/MAPK pathways.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Effects of an environmentally relevant PCB-mixture on immune function, clinical chemistry, and thyroid hormone levels in adult female B₆C₃F₁ mice.

Perfluoroalkyl Substances

Perfluorooctanoic acid (PFOA) exposure induces splenic atrophy via overactivation of macrophages in male mice.

Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells

Adult female rats perinatally exposed to perfluorohexane sulfonate (PFHxS) and a mixture of endocrine disruptors display increased body/fat weights without a transcriptional footprint in fat cells.

Toxic effects and mechanisms of PFOA and its substitute GenX on the photosynthesis of Chlorella pyrenoidosa.

Flame Retardants

Tetrabromobisphenol A induces THR β-mediated inflammation and uterine injury in mice at environmentally relevant exposure concentrations.

Chlorinated Flame-Retardant Dechlorane 602 Potentiates Type 2 Innate Lymphoid Cells and Exacerbates Airway Inflammation.

Decabromodiphenyl ether (BDE-209) exposure to lactating mice perturbs steroidogenesis and spermatogenesis in adult male offspring.

Effects of SiO₂ nanoparticles on the uptake of tetrabromobisphenol A and its impact on the thyroid endocrine system in zebrafish larvae.

Organotins

Effects of tributyltin on gonad and brood pouch development of male pregnant lined seahorse (Hippocampus erectus) at environmentally relevant concentrations.

Tributyltin triggers lipogenesis in macrophages via modifying PPARγ pathway.

Pesticides

Epigenome-wide association study (EWAS) for potential transgenerational disease epigenetic biomarkers in sperm following ancestral exposure to the pesticide methoxychlor.

Screening of potential oestrogen receptor α agonists in pesticides via in silico, in vitro and in vivo methods.

Maternal exposure during organogenesis to chlorpyrifos insecticide induce apoptosis process.

Exposure to nitenpyram during pregnancy causes colonic mucosal damage and non-alcoholic steatohepatitis in mouse offspring: The role of gut microbiota.

Evaluation and comparison of the mitochondrial and developmental toxicity of three strobilurins in zebrafish embryo/larvae.

The protective function of taurine on pesticide-induced permanent neurodevelopmental toxicity in juvenile rats.

Influence of acute exposure to a low dose of systemic insecticide fipronil on locomotor activity and emotional behavior in adult male mice.

Effect of cypermethrin on the postnatal development of the medulla oblongata and the possible protective role of melatonin in albino rats.

A combination of Tropilaelaps mercedesae and imidacloprid negatively affects survival, pollen consumption and midgut bacterial composition of honey bee.

Pre-differentiation exposure to low-dose of atrazine results in persistent phenotypic changes in human neuronal cell lines.

Potentially Toxic Elements

Arsenic-induced autophagy regulates apoptosis in AML-12 cells.

Ameliorative Effects of Caffeic Acid Against Arsenic-Induced Testicular Injury in Mice.

Arsenic suppresses GDF1 expression via ROS-dependent downregulation of specificity protein 1

Mechanisms involved in the possible protective effect of chrysin against sodium arsenite-induced liver toxicity in rats.

Sodium metavanadate treatment improves glycogen levels in multiple tissues in a model of metabolic syndrome caused by chronic cadmium exposure in Wistar rats.

Effect of Zinc on Hepatic and Renal Tissues of Chronically Arsenic Exposed Rats: A Biochemical and Histopathological Study.

Inorganic mercury effects on biomarker gene expressions of a freshwater amphipod at two temperatures.

Microplastics/Nanomaterials

Plastic pollution – A case study with Enchytraeus crypticus – From micro-to nanoplastics.

Time-dependent metabolic disorders induced by short-term exposure to polystyrene microplastics in the Mediterranean mussel Mytilus galloprovincialis.

Toxic effects of naturally-aged microplastics on zebrafish juveniles: A more realistic approach to plastic pollution in freshwater ecosystems.

Does microplastic ingestion dramatically decrease the biomass of protozoa grazers? A case study on the marine ciliate Uronema marinum.

A preliminary study of the association between colonization of microorganism on microplastics and intestinal microbiota in shrimp under natural conditions.

Combined effect of microplastics and DDT on microbial growth: A bacteriological and metabolomics investigation in Escherichia coli.

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.

PET nanoplastics interactions with water contaminants and their impact on human cells.

Maternal Responses and Adaptive Changes to Environmental Stress via Chronic Nanomaterial Exposure: Differences in Inter and Transgenerational Interclonal Broods of Daphnia magna.

Dietary exposure to polyethylene terephthalate microplastics (PET-MPs) induces faster growth but not oxidative stress in the giant snail Achatina reticulata.

Chemicals associated with biodegradable microplastic drive the toxicity to the freshwater oligochaete Lumbriculus variegatus.

Revisiting the cellular toxicity of benzo[a]pyrene from the view of nanoclusters: size- and nanoplastic adsorption-dependent bioavailability.

Air Pollution

In utero exposure to diesel exhaust particles, but not silica, alters post-natal immune development and function.

Exposure to Traffic-Generated Air Pollution Promotes Alterations in the Integrity of the Brain Microvasculature and Inflammation in Female ApoE^-/- mice.

Pharmaceuticals/Personal Care Products

New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio).

Mixtures

Risk Characterization and Probabilistic Concentration-Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays.

Exposure to estrogenic mixtures results in tissue-specific alterations to the metabolome of oysters.

Immunity and inflammatory responses in gilthead sea bream (Sparus aurata L.) exposed to sub-lethal mixture of carbamazepine, cadmium chloride and polybrominated diphenyl ether.

Effects of an environmentally relevant mixture of organophosphate esters derived from house dust on endochondral ossification in murine limb bud cultures.

Effects of contaminated surface water and groundwater from a rare earth mining area on the biology and the physiology of Sprague-Dawley rats.

Co-exposure of Bi₂O₃ nanoparticles and bezo[a]pyrene-enhanced in vitro cytotoxicity of mouse spermatogonia cells.

Miscellaneous

Developmental Programming: Adipose Depot-Specific Transcriptional Regulation by Prenatal Testosterone Excess in a Sheep Model of PCOS.

Dietary ingestion of 2-aminoanthracene (2AA) and the risk for type-1 diabetes (T1D).

Exposure/Environment Studies

BPA/Phenols

Bisphenol A and six other environmental phenols in urine of children and adolescents in Germany – human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V).

Bisphenol A and Its Analogues in Chinese Total Diets: Contaminated Levels and Risk Assessment.

Plasticizer contamination in the urine and hair of preschool children, airborne particles in kindergartens, and drinking water in Hong Kong. [phthalates and bisphenols]

Phthalates

Levels and determinants of urinary phthalate metabolites in Chinese community-dwelling older adults.

Urinary concentrations of phthalate metabolites in pregnant women living near Chapala Lake, Jalisco, Mexico.

Parabens/Triclosan/Antimicrobials

Persistence of the parabens in soil and their potential toxicity to earthworms.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Chlorinated and brominated persistent compounds in hard coral, soft coral, and parrotfish from remote Mascarene islands.

An Update on the Content of Fatty Acids, Dioxins, PCBs and Heavy Metals in Farmed, Escaped and Wild Atlantic Salmon (Salmo salar L.) in Norway.

Sources of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Other Dioxins in Lower Passaic River, NJ, Sediments.

Concentrations and Toxic Equivalency of Polycyclic Aromatic Hydrocarbons (PAHs) and Polychlorinated Biphenyl (PCB) Congeners in Groundwater Around Waste Dumpsites in South-West Nigeria.

The occurrence and sources of polychlorinated biphenyls (PCBs) in agricultural soils across China with an emphasis on unintentionally produced PCBs.

Dietary risk assessment of organochlorine pesticide residues in maize-based complementary breakfast food products in Nigeria.

Associations of residential and occupational history with the distribution of persistent pollutants mixtures in adipose tissue samples. [POPs and metals]

Perfluoroalkyl Substances

Development of Per and Polyfluoroalkyl Substances (PFAS) Ecological Risk Based Screening Levels (RBSLs).

Serum perfluoroalkyl substances in residents following long-term drinking water contamination from firefighting foam in Ronneby, Sweden

Profiling of emerging and legacy per-/polyfluoroalkyl substances in serum among pregnant women in China.

Deposition of PFAS ‘forever chemicals’ on Mt. Everest.

Per- and polyfluoroalkyl substances (PFASs) are positively associated with thyroid hormones in an arctic seabird.

High levels of fluoroalkyl substances and potential disruption of thyroid hormones in three gull species from South Western France.

Target, Nontarget, and Suspect Screening and Temporal Trends of Per- and Polyfluoroalkyl Substances in Marine Mammals from the South China Sea.

Environmental Risk Assessment Resulting from Sediment Contamination with Perfluoroalkyl Substances.

Characterizing the Air Emissions, Transport, and Deposition of Per- and Polyfluoroalkyl Substances from a Fluoropolymer Manufacturing Facility.

Pesticides

Pesticide exposure among Latinx children: Comparison of children in rural, farmworker and urban, non-farmworker communities.

Neonicotinoids in the agroecosystem: In-field long-term assessment on honeybee colony strength and microbiome.

Spiromesifen induces histopathological and cytotoxic changes in the midgut of the honeybee Apis mellifera (Hymenoptera: Apidae).

Birds feeding on tebuconazole treated seeds have reduced breeding output.

Estimating household exposure to pyrethroids and the relative contribution of inhalation pathway in a sample of Japanese children.

Potentially Toxic Elements

Human biomonitoring initiative (HBM4EU): Human biomonitoring guidance values (HBM-GVs) derived for cadmium and its compounds.

Rolling back the gains: Maternal stress undermines pregnancy health after Flint’s water switch.

Problem Definition and Community Participation in Environmental Health Interventions: An Exploratory Study of Groundwater Arsenic Remediation.

Assessment of potentially toxic element pollution in soils and related health risks in 271 cities across China.

Mercury exposure in an endangered seabird: long-term changes and relationships with trophic ecology and breeding success.

Effects of Contamination by Heavy Metals and Metalloids on Chromosomes, Serum Biochemistry and Histopathology of the Bonylip Barb Fish Near Sepon Gold-Copper Mine, Lao PDR.

Endocrine disrupting effects of copper and cadmium in the oocytes of the Antarctic Emerald rockcod Trematomus bernacchii.

Use of mercury isotopes to quantify sources of human inorganic mercury exposure and metabolic processes in the human body

The fate of anthropogenic Pb in soils; years after Pb terminated as a fuel additive; Northern Israel.

Cadmium exposure as a key risk factor for residents in a world large-scale barite mining district, southwestern China.

Identifying dust as the dominant source of exposure to heavy metals for residents around battery factories in the Battery Industrial Capital of China.

Preferential Liver Accumulation of Mercury Explains Low Concentrations in Muscle of Caiman yacare (Alligatoridae) in Upper Amazon.

Microplastics

Microplastics and other anthropogenic particles are prevalent in mussels from San Francisco Bay, and show no correlation with PAHs.

Occurrence and distribution of microplastic particles and the concentration of Di 2-ethyl hexyl phthalate (DEHP) in microplastics and wastewater in the wastewater treatment plant.

COVID-19 pandemic repercussions on plastic and antiviral polymeric textile causing pollution on beaches and coasts of South America.

Modelling the accumulation of microplastics through food webs with the example Baiyangdian Lake, China.

Cigarette butts as a microfiber source with a microplastic level of concern. ‘

Ecological risk assessment of microplastics in coastal, shelf, and deep sea waters with a consideration of environmentally relevant size and shape.

Microplastic footprints in the Qinghai-Tibet Plateau and their implications to the Yangtze River Basin.

Revisiting Microplastics in Landfill Leachate: Unnoticed Tiny Microplastics and Their Fate in Treatment Works.

Air Pollution

Exploring the external exposome using wearable passive samplers – The China BAPE study.

COVID-19, Air Pollution, and Racial Inequity: Connecting the Dots.

Changing air pollution scenario during COVID-19: Redefining the hotspot regions over India.

Changes in air quality during COVID-19 ‘lockdown’ in the United Kingdom.

Surface and Satellite Observations of Air Pollution in India during COVID-19 Lockdown: Implication to Air Quality.

Analysis of lockdown for CoViD-19 impact on NO₂ in London, Milan and Paris: What lesson can be learnt?

Pharmaceuticals/Personal Care Products

Occurrence and distribution of endocrine-disrupting chemicals in mariculture fish and the human health implications.

Occurrence, seasonal variations, and ecological risk of pharmaceuticals and personal care products in River Ganges at two holy cities of India.

Estimation of community-wide multi-chemical exposure via water-based chemical mining: Key research gaps drawn from a comprehensive multi-biomarker multi-city dataset.

Mixtures

Co-occurrence of antiseptic triclocarban and chiral anti-inflammatory ibuprofen in environment: Association between biological effect in sediment and risk to human health

Miscellaneous

Towards a systematic method for assessing the impact of chemical pollution on ecosystem services of water systems.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sa…@healthandenvironment.org and ask to join the group EDC_re…@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

EHN EHN

Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.
Lou Guillette Jr. Memorial Symposium
by Sarah Howard on October 22, 2024 at 1:30 pm
On March 14-15, 2025, HEEDS is hosting the Lou Guillette Jr. Memorial Symposium on endocrine disrupting science at the University of Florida. It will celebrate the life and legacy of Dr. Guillette, gather together his trainees and colleagues, and focus on the research topics that Lou made famous. Information here.
Webinar: The overturning of Chevron deference: impacts on environmental health decision making
by Sarah Howard on October 17, 2024 at 4:21 pm
In this Nov. 13 webinar, legal experts will discuss the implications of the overturning of Chevron deference and its profound impact on science, public health and decision-making. Sponsored by CHE and UCSF's EaRTH Center.

EHN EHN

Ultra-processed foods and plastic packaging make for the ultimate toxic pair, scientists say
by Katherine McMahon,Sarah Howard on October 25, 2024 at 10:37 am
A recent paper published in Globalization and Health explores the relationship between ultra-processed foods (UPFs), plastic packaging, and their combined threat to public health. “Consumers do not have the power to solve a problem of this scale, and thus it is the responsibility of policymakers to ensure that transitions away from unhealthy, unsustainable foods are accompanied by structural measures that support demand and access to healthy foods.”
Microplastic exposure linked to reduced sperm quality in humans
by Katherine McMahon,Sarah Howard on October 23, 2024 at 4:29 pm
Exposure to microplastics is associated with a decrease in sperm concentration, motility, and shape, according to a new study published in The Lancet. “The identification of non-stick pan coating material PTFE as a particularly hazardous microplastic for male fertility underscores the importance of targeted interventions to reduce exposure to this and similar substances.”
Exposure to PFAS in ski wax may be linked to high cholesterol
by Katherine McMahon,Sarah Howard on October 16, 2024 at 7:42 pm
According to a new study published in Environmental Research, skiers and snowboarders may face health risks from their exposure to PFAS via ski wax, which can contain up to 100% PFAS by mass. “Interventions to remove PFAS from fluorinated wax could decrease direct exposure to skiers and reduce PFAS release into the environment.”

EHN EHN

Stricter toxic chemical rules reduce Californians’ exposures
by Kristina Marusic on October 31, 2024 at 11:25 am
Californians have lower levels of toxic chemicals linked to cancer, birth defects and reproductive harm in their bodies than people in the rest of the country, according to a new study. The study, published in Environmental Health Perspectives and conducted by researchers at Silent Spring Institute, a nonprofit scientific research organization, and the University of California at Berkeley (UC Berkeley), looked at nationwide data on the levels of 37 toxic chemicals in people’s blood before and after California introduced its stringent regulations. It found that for 18 of these chemicals, Californians have lower levels in their bodies than the rest of the country.
EPA dismissed data on the neurotoxicity of common insecticides
by Katherine McMahon,Sarah Howard on October 30, 2024 at 5:56 pm
A recent paper in Frontiers in Toxicology examined research submitted by industry to the U.S. Environmental Protection Agency (EPA) on the neurotoxicity of neonicotinoids - the most widely used class of insecticides in the U.S. and worldwide - and found that the data was evaluated improperly by the agency. Why this matters: Neonicotinoids are widely used not only for commercial agriculture but also for more personal uses like home gardens and in some flea and tick treatments for pets. Humans are regularly exposed to neonicotinoids – which are structurally similar to nicotine – through the environment, food and water. Neonicotinoids’ popularity partly comes from the belief that their harmful effects are mostly limited to insects, but studies like this one demonstrate that mammals may also be harmed by the chemicals, and highlight the urgent need for stronger regulations around their use.
Pesticide regulations ignore critical threats to insect health and ecosystems
by EHN Curators on October 30, 2024 at 10:26 am
In a study revealing regulatory gaps, researchers found that pesticides impact insect behavior and survival at non-lethal doses, especially in warmer temperatures, calling into question the effectiveness of current pesticide safety protocols. Dave Goulson writes for The Conversation.