A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.
Contents: Regulations/Policy, Methods/Screening, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies.
Regulations/Policy
Guidelines on the benefit-risk assessment of the presence of phthalates in certain medical devices covering phthalates which are carcinogenic, mutagenic, toxic to reproduction (CMR) or have endocrine-disrupting (ED) properties. [full text pdf version here]
Methods/Screening
Computational evaluation of interactions between organophosphate esters and nuclear hormone receptors. [uses Endocrine Disruptome, an online computational tool]
A novel lipidomics-based approach to evaluating the risk of clinical hepatotoxicity potential of drugs in 3D human microtissues. [for pharmaceuticals]
Reviews
Commentaries/Conference Summaries
New Toxicology Tools and the Emerging Paradigm Shift in Environmental Health Decision-Making. [Commentary re a 2018 National Academies workshop]
Pesticides
Potentially Toxic Elements
Microplastics
Air Pollution
Mixtures
Miscellaneous
The chemical exposome of type 2 diabetes mellitus: Opportunities and challenges in the omics era. [physical and chemical environment, including POPs, phthalates, metals, air pollution, pesticides, etc.]
Human Health Studies
Perfluoroalkyl Substances
Flame Retardants
Pesticides
Pesticide exposure and diabetes mellitus in a semi-urban Nepali population: a cross-sectional study.
Potentially Toxic Elements
Air Pollution
Mixtures
Complex contaminant mixtures and their associations with intima-media thickness. [POPs, metals, etc.]
Miscellaneous
Laboratory Studies
BPA/Phenols
Endocrine Disruptors Induced Distinct Expression of Thyroid and Estrogen Receptors in Rat versus Mouse Primary Cerebellar Cell Cultures. [BPA, arsenic, zearalenone]
Emergent contaminants in sediments and fishes from the Tamsui River (Taiwan): Their spatial-temporal distribution and risk to aquatic ecosystems and human health. [BPA, phthalates, PBDEs]
Phthalates
Triclosan/Antimicrobials
Persistent Organic Pollutants: PCBs, Dioxin, OCPs
Perfluoroalkyl Substances
Flame Retardants
Organotins
Pesticides
Potentially Toxic Elements
Effects of chronic cadmium exposure at food limitation-relevant levels on energy metabolism in mice.
Microplastics
Air Pollution
Pharmaceuticals
Mixtures
Corticosterone mediates telomere length in raptor chicks exposed to chemical mixture. [metals and pesticides]
Miscellaneous
Exposure/Environment Studies
BPA/Phenols
Phthalates
Occurrence of organic plastic additives in surface waters of the Rhône River (France). [phthaltes, bisphenols, organophosphates]
Assessment of water contamination and health risk of endocrine disrupting chemicals in outdoor and indoor swimming pools. [4 phenols, 6 estrogens, 4 progestogens, 5 androgens, and 1 pharmaceutical]
Parabens
Persistent Organic Pollutants: PCBs, Dioxin, OCPs
Perfluoroalkyl Substances
Flame Retardants
Pesticides
Potentially Toxic Elements
Microplastics
Air Pollution
Pharmaceuticals
Aquatic macroinvertebrates under stress: Bioaccumulation of emerging contaminants and metabolomics implications. [pharmaceuticals and other EDCs]
Mixtures
——-
This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sarah@healthandenvironment.org and ask to join the group EDC_research@googlegroups.com. Archives are at https://groups.google.com/d/ forum/edc_research. Feel free to forward. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.