EDC Science Weekly, Aug. 5 – 18, 2021

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed for the past two weeks (so it’s longer than normal this time).

Contents: Events,Regulations/Policy, Methods/Tools/Screening, Commentaries/Conference Summaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Webinar September 22: Multi- and transgenerational outcomes of an exposure to a mixture of EDCs on puberty and maternal behavior in the female rat

Regulations/Policy

The EU chemicals strategy for sustainability: in support of the BfR position.

Comparing Environmental Risk Regulations in China and the United States.

Methods/Tools/Screening

The 2021 update of the EPA’s adverse outcome pathway database.

Harnessing electronic health records to study emerging environmental disasters: a proof of concept with perfluoroalkyl substances (PFAS).

Phenomics Approach to Investigate Behavioral Toxicity of Environmental or Occupational Toxicants in Adult Zebrafish (Danio rerio).

Dictyostelium discoideum: an alternative non-animal model for developmental toxicity testing.

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health.

Commentaries/Conference Summaries

Marine Debris and Human Health: An Exposure Pathway of POPs?

Paving the Way for Application of Next Generation Risk Assessment to Safety Decision-Making for Cosmetic Ingredients.

Air pollution and COVID-19: clearing the air and charting a post-pandemic course: a joint workshop report of ERS, ISEE, HEI and WHO.

Climate change and environmental pollution induced risks on children’s health: are pediatricians prepared to meet the challenge?

“Old” and “new” contaminants and their management: learning from the past, looking to the future.

The Global Legacy of POPs: Special Issue.

Reviews

Numerous EDCs

Exploring the evidence for epigenetic regulation of environmental influences on child health across generations.

Endocrine disrupting chemicals in the pathogenesis of hypospadias; developmental and toxicological perspectives.

Critical review on hazardous pollutants in water environment: Occurrence, monitoring, fate, removal technologies and risk assessment.

Exposure of Environmental Contaminants and Development of Neurological Disorders.

Exposure to Environmental Toxins and Autoimmune Conditions.

Contribution of prenatal endocrine-disrupting chemical exposure to genital anomalies in males: The pooled results from current evidence.

Environmental Toxicants and NAFLD: A Neglected yet Significant Relationship.

Study on toxicity effects of environmental pollutants based on metabolomics: A review.

Meta-analysis shows environmental contaminants elevate cortisol levels in teleost fish – Effect sizes depend on contaminant class and duration of experimental exposure.

Research progress on the association between environmental pollutants and the resistance mechanism of PARP inhibitors in ovarian cancer.

Environmental Toxins Are a Major Cause of Bone Loss.

Current applications and future perspectives on elemental analysis of non-invasive samples for human biomonitoring.

Ecological Risks Due to Immunotoxicological Effects on Aquatic Organisms.

BPA/Phenols

A Systematic Review of Bisphenol A from Dietary and Non-Dietary Sources during Pregnancy and Its Possible Connection with Fetal Growth Restriction: Investigating Its Potential Effects and the Window of Fetal Vulnerability.

Perfluoroalkyl Substances

The Role of Perfluorinated Compound Pollution in the Development of Acute and Chronic Kidney Disease.

Modern methods for the synthesis of perfluoroalkylated aromatics.

Removal of per- and poly-fluoroalkyl substances (PFASs) by wetlands: Prospects on plants, microbes and the interplay.

Flame Retardants

Occupational risk of organophosphates and other chemical and radiative exposure in the aircraft cabin: A systematic review.

A review of environmental occurrence, analysis, bioaccumulation, and toxicity of organophosphate esters.

Potentially Toxic Elements

Role of Heavy Metals in Diabetes: Mechanisms and Treatment Strategies.

Mercury and Movement Disorders: The Toxic Legacy Continues.

Paradoxical effects of arsenic in the lungs.

Arsenic and weight loss: At a crossroad between lipogenesis and lipolysis

Plant Polyphenols: Potential Antidotes for Lead Exposure.

Microplastics/Nanomaterials/Plastics

Toxicity of nanoplastics for zebrafish embryos, what we know and where to go next.

Micro- and Nanoplastic-Mediated Pathophysiological Changes in Rodents, Rabbits, and Chickens: A Review.

Microplastic pollution in freshwater systems in Southeast Asia: contamination levels, sources, and ecological impacts

Nanomaterials-induced toxicity on cardiac myocytes and tissues, and emerging toxicity assessment techniques.

Continental microplastics: Presence, features, and environmental transport pathways.

Are Biobased Plastics Green Alternatives?-A Critical Review.

Freshwater wild biota exposure to microplastics: A global perspective.

Challenges and possible solutions to mitigate the problems of single-use plastics used for packaging food items: a review.

Air Pollution

Exposure to Stress and Air Pollution from Bushfires during Pregnancy: Could Epigenetic Changes Explain Effects on the Offspring?

Pharmaceuticals/Personal Care Products

Evidence of intergenerational transmission of Diethylstilbestrol (DES) health effects: Hindsight and insight.

Drug pollution & Sustainable Development Goals.

Analytical methods for the determination of endocrine disrupting chemicals in cosmetics and personal care products: A review.

Impact of Estrogens Present in Environment on Health and Welfare of Animals.

Miscellaneous

Spike in pollution to ignite the bursting of COVID-19 second wave is more dangerous than spike of SAR-CoV-2 under environmental ignorance in long term: a review.

Human Health Studies

Numerous Chemicals/Mixtures

Urinary phenols and parabens metabolites associated with cardiovascular disease among adults in the United States.

Urinary concentrations of phenols, parabens, and triclocarban in relation to uterine leiomyomata incidence and growth.

The early-life exposome and epigenetic age acceleration in children.

Exposure to concentrated animal feeding operations (CAFOs) and risk of mortality in North Carolina, USA.

BPA/Phenols

Urinary Bisphenol A Concentrations and Parameters of Ovarian Reserve among Women from a Fertility Clinic.

Could endocrine disruptors be a new player for acne pathogenesis? The effect of bisphenol A on the formation and severity of acne vulgaris: A prospective, case-controlled study.

Phthalates

Urinary phthalate metabolite concentrations are negatively associated with follicular fluid anti-müllerian hormone concentrations in women undergoing fertility treatment.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Effects of prenatal exposure to persistent organic pollutants on neonatal Outcomes:A mother-child cohort (Shanghai, China).

Which factors influence the frequency of participation in longitudinal cohort studies? – An analysis of demographics, social factors, and medical preconditions in participants of the health effects in high level exposure to polychlorinated biphenyls (HELPcB) cohort.

Perfluoroalkyl Substances

Perfluoroalkyl substances (PFAS) in drinking water and risk for polycystic ovarian syndrome, uterine leiomyoma, and endometriosis: A Swedish cohort study.

Serum perfluoroalkyl substances and breast cancer risk in Japanese women: A case-control study.

Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects ex vivo in murine intestinal tissue.

Associations of Prenatal Exposure to Per- and Polyfluoroalkyl Substances with the Neonatal Birth Size and Hormones in the Growth Hormone/Insulin-Like Growth Factor Axis.

Effect of polyfluoroalkyl chemicals on the occurrence of urge urinary incontinence: a population-based study.

Pesticides

Health Impacts of Perchlorate and Pesticide Exposure: Protocol for Community-Engaged Research to Evaluate Environmental Toxicants in a US Border Community.

Cancer risk and nullity of Glutathione-S-transferase mu and theta 1 in occupational pesticide workers.

Potentially Toxic Elements

An atlas of metallome and metabolome interactions and associations with incident diabetes in the Strong Heart Family Study.

Hair mercury levels, intake of omega-3 fatty acids and ovarian reserve among women attending a fertility center.

Association between serum folate levels and blood concentrations of cadmium and lead in US adults.

Assessment of Metal Concentrations and Associations with Pulmonary Function among Children with Asthma in Chicago, Illinois.

Associations of exposure to cadmium, antimony, lead and their mixture with gestational thyroid homeostasis.

Increased serum levels of cadmium are associated with an elevated risk of cardiovascular disease in adults.

Evaluation of zinc and cadmium levels in the biological samples of Ewing sarcomas patients and healthy subjects.

The Relationship between the Urinary Cadmium Concentration and Cause-Specific Mortality in Subjects without Severe Renal Damage: A 35-Year Follow-Up Study in a Cadmium-Polluted Area of Japan.

Air Pollution

Fine Particulate Matter and Dementia Incidence in the Adult Changes in Thought Study. [accompanied by Invited Perspective: Air Pollution and Dementia: Challenges and Opportunities.]

Longitudinal relationship of particulate matter and metabolic control and severe hypoglycaemia in children and adolescents with type 1 diabetes.

Air pollution and autism spectrum disorder in Israel: A negative control analysis.

Racial/Ethnic Disparities in Alzheimer’s Disease Risk: Role of Exposure to Ambient Fine Particles.

Effect of Environmental Pollutants PM2.5, CO, NO₂, and O₃ on the Incidence and Mortality of SARS-CoV-2 Infection in Five Regions of the USA.

Prenatal household air pollutant exposure is associated with reduced size and gestational age at birth among a cohort of Ghanaian infants.

The effect of prenatal temperature and PM_2.5 exposure on birthweight: Weekly windows of exposure throughout the pregnancy.

Environmental Air Pollutants Inhaled during Pregnancy Are Associated with Altered Cord Blood Immune Cell Profiles.

Pharmaceuticals/Personal Care Products

Associations of hair dye and relaxer use with breast tumor clinicopathologic features: Findings from the Women’s circle of Health Study.

Incidence of testicular cancer in trans women using gender-affirming hormonal treatment: a nationwide cohort study.

Does administration of vaginal estrogens increase the risk of venous thromboembolism: a case-control study.

Laboratory Studies

BPA/Phenols

Perfluorooctane sulfonate and bisphenol A induce a similar level of mast cell activation via a common signaling pathway, Fyn-Lyn-Syk activation.

BPA and BPS affect the expression of anti-Mullerian hormone (AMH) and its receptor during bovine oocyte maturation and early embryo development.

Study on the chemical behaviour of Bisphenol S during the in vitro gastrointestinal digestion and its bioaccessibility.

Influence of anions on ozonation of bisphenol AF: Kinetics, reaction pathways, and toxicity assessment.

Bisphenol A and genistein have opposite effects on adult chicken ovary by acting on ERα/Nrf2-Keap1-signaling pathway.

Phthalates

Toxicokinetic studies of di-isobutyl phthalate focusing on the exploration of gender differences in rats.

Transcriptome and in silico approaches provide new insights into the mechanism of male reproductive toxicity induced by chronic exposure to DEHP.

Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion.

Parabens/Triclosan/Antimicrobials

Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation.

Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR.

Large chromosomal deletions and impaired homologous recombination repairing in HEK293T cells exposed to polychlorinated biphenyl 153.

The endocrine disruptor hexachlorobenzene can cause oxidative damage in the testis of mice.

Bone toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the retinoid system: A causality analysis anchored in osteoblast gene expression and mouse data.

Transcriptional profiling of Chinese hamster ovary (CHO) cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Perfluoroalkyl Substances

Perfluoroalkyl Substance Exposure and the BDNF Pathway in the Placental Trophoblast.

Combined effects of mixed per- and polyfluoroalkyl substances on the Nrf2-ARE pathway in ARE reporter-HepG2 cells.

Comprehensive multi-omics approaches reveal the hepatotoxic mechanism of perfluorohexanoic acid (PFHxA) in mice.

Effects of an environmentally relevant PFAS mixture on dopamine and steroid hormone levels in exposed mice.

Immunotoxicity of F53B, an alternative to PFOS, on zebrafish (Danio rerio) at different early life stages.

Perfluorooctane sulfonate (PFOS) disturbs fatty acid metabolism in Caenorhabditis elegans: Evidence from chemical analysis and molecular mechanism exploration.

Probiotic supplementation mitigates the developmental toxicity of perfluorobutanesulfonate in zebrafish larvae.

Interactions of perfluorooctanoic acid with acyl-CoA thioesterase 1 (Acot1).

Developing potency factors for thyroid hormone disruption by PFASs using TTR-TRβ CALUX® bioassay and assessment of PFASs mixtures in technical products.

Flame Retardants

A PBPK model describing the pharmacokinetics of γ-HBCD exposure in mice.

Significance of biotransformation and excretion on the enantioselective bioaccumulation of hexabromocyclododecane (HBCDD) in laying hens and developing chicken embryos.

Impact of dietary exposure to low-dose tris(1,3-dichloro-2-propyl)phosphate in allergic asthmatic mice.

Human CYP enzyme-activated clastogenicity of 2-ethylhexyl diphenyl phosphate (a flame retardant) in mammalian cells.

The brominated flame retardant, TBCO, impairs oocyte maturation in zebrafish (Danio rerio).

Adrenal Corticosteroid Perturbation by the Endocrine Disruptor BDE-47 in a Human Adrenocortical Cell Line and Male Rats.

Bone developmental toxicity of organophosphorus flame retardants TDCIPP and TPhP in marine medaka Oryzias melastigma.

Pesticides

The ameliorative effect of N-acetylcysteine against penconazole induced neurodegenerative and neuroinflammatory disorders in rats.

Tralopyril affects locomotor activity of zebrafish (Danio rerio) by impairing tail muscle tissue, the nervous system, and energy metabolism.

Temephos decreases sperm quality and fertilization rate and is metabolized in rat reproductive tissues at low dose exposure.

Context-Dependent Effect of Dietary Phytochemicals on Honey Bees Exposed to a Pesticide, Thiamethoxam.

Exposure to chlorpyrifos leads to spindle disorganization and mitochondrial dysfunction of porcine oocytes during in vitro maturation.

Lambda-cyhalothrin-loaded nanocapsules pose an unacceptable acute toxicological risk to zebrafish (Danio rerio) at the adult and larval stages but present an acceptable risk to embryos.

Acute toxicity of the insecticide abamectin and the fungicide difenoconazole (individually and in mixture) to the tropical stingless bee Melipona scutellaris.

Toxic effects of chlorpyrifos, cypermethrin and glyphosate on the non-target organism Selenastrum capricornutum (Chlorophyta).

Response of the nuclear xenobiotic receptors to alleviate glyphosate-based herbicide-induced nephrotoxicity in weaned piglets.

Paternal fenvalerate exposure transgenerationally impairs cognition and hippocampus in female offspring.

Atrazine Inhalation Causes Neuroinflammation, Apoptosis and Accelerating Brain Aging.

Potentially Toxic Elements

Low-level cadmium doses do not jeopardize the insulin secretion pathway of β-cell models until the onset of cell death.

NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.

Effects of cadmium on the female reproductive axis of a Neotropical fish.

Ameliorative effects of morel mushroom (Morchella esculenta) against Cadmium-induced reproductive toxicity in adult male rats.

The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.

Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior.

Cadmium significantly changes major morphometrical points and cardiovascular functional parameters during early development of zebrafish.

Molybdenum and cadmium co-induce mitophagy and mitochondrial dysfunction via ROS-mediated PINK1/Parkin pathway in Hepa1-6 cells.

Environmental exposure to cadmium reduces the primary antibody-mediated response of wood mice (Apodemus sylvaticus) from differentially polluted locations in the Netherlands.

Impact of selenium on cerebellar injury and mRNA expression in offspring of rat exposed to methylmercury.

Microplastics/Nanomaterials

Noxic effects of polystyrene microparticles on murine macrophages and epithelial cells.

Nanoplastics Induce More Serious Microbiota Dysbiosis and Inflammation in the Gut of Adult Zebrafish than Microplastics.

Microplastic Polystyrene Ingestion Promotes the Susceptibility of Honeybee to Viral Infection.

Cardiovascular toxicity assessment of polyethylene nanoplastics on developing zebrafish embryos.

Microplastics induced developmental toxicity with microcirculation dysfunction in zebrafish embryos.

Micro/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): Insight from brain-gut-microbiota axis.

Effects of nanoplastic on toxicity of azole fungicides (ketoconazole and fluconazole) in zebrafish embryos.

Polystyrene microplastics disrupt the blood-testis barrier integrity through ROS-Mediated imbalance of mTORC1 and mTORC2.

Toxicity of boron and vanadium nanoparticles on Danio rerio embryos – Phenotypical, biochemical, and behavioral alterations.

Mixtures

Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat. [accompanied by Invited Perspective: Does Developmental Adaptation Pose Risks with Changing Toxicant Exposures?]

A targeted transcriptomics approach for the determination of mixture effects of pesticides.

A disease-specific screening-level modeling approach for assessing the cancer risks of pesticide mixtures.

Lipidomic analysis of single and combined effects of polyethylene microplastics and polychlorinated biphenyls on human hepatoma cells.

Co-Treatment of Copper Oxide Nanoparticle and Carbofuran Enhances Cardiotoxicity in Zebrafish Embryos.

Miscellaneous

Prenatal androgen excess impairs beta cell function by decreased Sirtuin3 expression.

Perchlorate exposure does not induce obesity or non-alcoholic fatty liver disease in zebrafish.

Gene expression analysis on growth, development and toxicity pathways of male Nile tilapia (Oreochromus niloticus), after acute and sub-chronic benzo (a) pyrene exposures.

Exposure/Environment Studies

Numerous Chemicals/Mixtures

Exposure of men and lactating women to environmental phenols, phthalates, and DINCH.

Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis.

Concentrations and related health risk assessment of pesticides, phthalates and heavy metals in strawberry from Shanghai, China.

BPA/Phenols

Effect of common consumer washing methods on bisphenol A release in tritan drinking bottles.

Parabens/Triclosan/Antimicrobials

Temporal Trends of Phenol, Paraben, and Triclocarban Exposure in California Pregnant Women during 2007-2014.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Polychlorinated biphenyls and organochlorine pesticides in breast milk samples and their correlation with dietary and reproductive factors in lactating mothers in Istanbul.

Biomonitoring of toxic metals, organochlorine pesticides, and polybrominated biphenyl 153 in Michigan urban anglers.

Impact of sociodemographic profile, generation and bioaccumulation on lifetime dietary and internal exposures to PCBs.

Accumulations and temporal trends of polychlorinated biphenyls (PCBs) in olive tree components.

Historic changes of polychlorinated biphenyls (PCBs) in juvenile and adult cetaceans from the Pearl River estuary from 2003 to 2020.

Measurement of polychlorinated biphenyls with hand wipes and matched serum collected from Chinese E-waste dismantling workers: Exposure estimates and implications.

Factors affecting multiple persistent organic pollutant concentrations in the air above Japan: A panel data analysis.

Effect of abiotic factors and environmental concentrations on the bioaccumulation of persistent organic and inorganic compounds to freshwater fish and mussels.

Perfluoroalkyl Substances

Chlorinated polyfluoroalkyl ether sulfonic acids in fish, dust, drinking water and human serum: From external exposure to internal doses.

A machine learning approach for prioritizing groundwater testing for per-and polyfluoroalkyl substances (PFAS).

PFASs intake from fish, eggs and drinking water in Greece in relation to the safety limits for weekly intake proposed in the EFSA scientific opinion of 2020.

Investigation of distribution, sources and flux of perfluorinated compounds in major southern Indian rivers and their risk assessment.

Computational estimates of daily aggregate exposure to PFOA/PFOS from 2011 to 2017 using a basic intake model.

Perfluoroalkyl acids in surface sediments from the lower Yangtze River: Occurrence, distribution, sources, inventory, and risk assessment.

Thermal decomposition of perfluorinated carboxylic acids: Kinetic model and theoretical requirements for PFAS incineration.

Ticks as novel sentinels to monitor environmental levels of per- and polyfluoroalkyl substances (PFAS).

Plant uptake of perfluoroalkyl substances in freshwater environments (Dongzhulong and Xiaoqing Rivers, China).

Flame Retardants

Polybrominated diphenyl ethers and the multi-element profile of house dust in Croatia: Indoor sources, influencing factors of their accumulation and health risk assessment for humans.

Concentrations, sources, and exposure risk of polychlorinated biphenyls in soil profiles of the floodplain of the lower reaches of the River Niger, Nigeria.

Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption.

Health risk assessment and development of human health ambient water quality criteria for PBDEs in China.

Pesticides

A tale of two metrics: the EPA Risk Quotient Approach versus the delay in Population Growth Index for determination of pesticide risk to aquatic species.

Inferring pesticide toxicity to honey bees from a field-based feeding study using a colony model and Bayesian inference.

Residues of glyphosate in food and dietary exposure.

Potentially Toxic Elements

Exposure to metals and metalloids among pregnant women from Spain: Levels and associated factors.

Relationship between personal-sampled air lead and blood lead in low-lead-exposure workers in Japan to apply multiple regression models determining permissible air lead concentration.

Health Risk Assessment of Mercury Exposure from Fish Consumption in Munduruku Indigenous Communities in the Brazilian Amazon.

Mercury accumulation in reef fishes: a comparison among red grouper, scamp, and gag of the Atlantic southeastern US and evaluation of “grouper” consumption guidelines.

Probabilistic multi-pathway human health risk assessment due to heavy metal(loid)s in a traditional gold mining area in Ecuador.

Co-Occurrence of Metal Contaminants in United States Public Water Systems in 2013-2015.

Is Time Spent Outside the Family Home a Risk Factor for Lead Exposure in Pre-School Children Living in Broken Hill?

Inner Workings: Keeping arsenic out of rice.

Uncertainty and sensitivity analyses of human health risk from bioaccessible arsenic exposure via rice ingestion in Bangkok, Thailand.

Aluminium in cosmetics and personal care products.

Aluminum Content of Human Milk and Antiperspirant Use.

Polyvinyl chloride in consumer and environmental plastics, with a particular focus on metal-based additives.

The effect of experimental lead pollution on DNA methylation in a wild bird population.

Effect of heavy metals pollution on the composition and diversity of the intestinal microbial community of a pygmy grasshopper (Eucriotettix oculatus).

Hair to blood mercury concentration ratios and a retrospective hair segmental mercury analysis in the Northwest Territories, Canada.

Mercury levels in humpback whales, and other Southern Ocean marine megafauna.

Microplastics

Temporal Variability of Microparticles Under the Seattle Aquarium, WA: Documenting the Global Covid-19 Pandemic.

Sampling, Identification and Characterization of Microplastics Release from Polypropylene Baby Feeding Bottle during Daily Use.

Air Pollution

Forecasting the impact of environmental stresses on the frequent waves of COVID19.

Pharmaceuticals/Personal Care Products

Pharmaceuticals in drinking water sources and tap water in a city in the middle reaches of the Yangtze River: occurrence, spatiotemporal distribution, and risk assessment.

Miscellaneous

The Tire Wear Compounds 6PPD-Quinone and 1,3-Diphenylguanidine in an Urban Watershed.

Comprehensive assessment of water quality through different approaches: Physicochemical and ecotoxicological parameters.

Polycyclic aromatic hydrocarbons in beverage and dairy products in South Korea: a risk characterization using the total diet study.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sa…@healthandenvironment.org and ask to join the group EDC_re…@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Feel free to forward. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

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