EDC Science Weekly, Jan. 3-16, 2025

Post author:HEEDS
Post published:January 16, 2025
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed over the past two weeks.

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries, Reviews/Meta-Analyses, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Highlights:

Science summaries and highlights

Events

Jan. 22 webinar: Gamechanger: California sues ExxonMobil over plastic recycling lies [Beyond Plastics]

Jan. 23 webinar: PFAS and cancer [Health and Environment Alliance and Association of European Cancer Leagues]

Jan. 30 webinar: Product data for public health: Clearya case studies [CHE]

Jan. 30 and Feb. 13 webinars: EDC exposure and gonadal function: consequences and interventions [Endocrine Society EDC Special Interest Group]

Feb. 10-13: Childhood cancer prevention symposium, in person in Houston TX [CEHN and others]

Feb. 19 webinar: Ultrashort-chain PFAS: The global threat of trifluoracetic acid [EDC Strategies Partnership]

Mar. 14-15: Lou Guillette Jr. Symposium, in person at the University of Florida in Gainesville [HEEDS]

Apr. 27-29, 2025 conference: Break the Cycle of Children’s Environmental Health Disparities

More events

Regulations/Policy

Manufactured Chemicals and Children’s Health – The Need for New Law.

Optimism for a global plastics treaty.

More EDC policy and regulations open for comment

Methods/Tools/Screening

Improving the Health and Environmental Health Literacy of Professionals: Evaluating the Effect of a Virtual Intervention on Phthalate Environmental Health Literacy

Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: a case study examining associations between PFOA and PFOS exposures and vaccine response.

High-Throughput Effect-Directed Analysis of Androgenic Compounds in Hospital Wastewater: Identifying Effect Drivers through Non-Target Screening Supported by Toxicity Prediction.

An Adverse Outcome Pathway for food nanomaterial-induced intestinal barrier disruption.

A three-dimensional mouse liver organoid platform for assessing EDCs metabolites simulating liver metabolism.

Environmental justice mapping tools in the United States: A review of national and state tools.

Commentaries

Editorial: Endocrine disruptors in obesity. [Intro to a research topic in Frontiers in Endocrinology]

The Rise and Risks of Fluorinated Pesticides: A Call for Comprehensive Research to Address Environmental and Health Concerns.

Precision environmental health: Establishing the role of environmental exposures in personalized medicine for oncology.

Editorial: Reducing animal use in carcinogenicity testing.

Caution Needed in Interpreting the Evidence Base on Fluoride and IQ

Time to Reassess Systemic Fluoride Exposure, Again

Reviews/Meta-Analyses

Numerous Chemicals/Mixtures

Polyvinyl chloride (PVC), its additives, microplastic and hum Caution Needed in Interpreting the Evidence Base on Fluoride and IQ – PubMed an health: Unresolved and emerging issues.

Endocrine Disruptors in Child Obesity and Related Disorders: Early Critical Windows of Exposure.

Exploring the Impact of Environmental Factors on Male Reproductive Health through Epigenetics.

Impact of Endocrine Disrupting Pesticide Use on Obesity: A Systematic Review

BPA/Phenols

The Effect of Bisphenol and Its Cytotoxicity on Female Infertility and Pregnancy Outcomes: A Narrative Review.

Does Bisphenol A (BPA) Exposure Cause Human Diseases?

Disruptive multiple cell death pathways of bisphenol-A.

Bisphenol A and Its Emergent Substitutes: State of the Art of the Impact of These Plasticizers on Oxidative Stress and Its Role in Vascular Dysfunction

Phthalates

Comprehensive Review of Phthalate Exposure: Health Implications, Biomarker Detection and Regulatory Standards.

The role of di-(2-ethylhexyl) phthalate in cancer initiation and progression: Mechanisms and health implications.

Phthalates toxicity in vivo to rats, mice, birds, and fish: A thematic scoping review.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Effects of POPs-induced SIRT6 alteration on intestinal mucosal barrier function: A comprehensive review.

PFAS

PFAS Exposure and Male Reproductive Health: Implications for Sperm Epigenetics.

Per- and Polyfluoroalkyl Substances and Female Health Concern: Gender-based Accumulation Differences, Adverse Outcomes, and Mechanisms.

Insights into Toxicological Mechanisms of Per-/polyfluoroalkyl Substances by Using Omics-centered Approaches.

The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models.

Out of sight, into the spotlight: Beyond the current state of science on per- and poly-fluoroalkyl substances in groundwater.

A systematic review for non-targeted analysis of per- and polyfluoroalkyl substances (PFAS).

Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies

Contamination of the terrestrial food chain by per- and polyfluoroalkyl substances (PFAS) and related human health risks: A systematic review.

Pesticides

Neonicotinoid Pesticides in African Agriculture: What do we know and what should be the focus for future research?

Metals/Metalloids

Fluoride Exposure and Children’s IQ Scores: A Systematic Review and Meta-Analysis

How Effective Are Secondary Interventions at Improving Health Outcomes In Children Exposed to Lead in Early Childhood?

Arsenic and the placenta: A review with emphasis on the immune system.

Could the Effect of Arsenic on the Testis be Reversed after Removing the Insult? A Meta-analysis Study.

The Potential Metalloestrogenic Effect of Aluminum on Breast Cancer Risk for Antiperspirant Users.

Nutrient-heavy metal interaction and mixed heavy metal exposure in relation to cognition across lifespan: review evidence, potential mechanisms, and implications.

Microplastics/Nanomaterials

Impacts of microplastic accumulation in aquatic environment: Physiological, eco-toxicological, immunological, and neurotoxic effects.

Microplastics in aquatic environments: detection, abundance, characteristics, and toxicological studies.

Advancements and challenges in microplastic detection and risk assessment: Integrating AI and standardized methods.

Microplastics as an Emerging Potential Threat: Toxicity, Life Cycle Assessment, and Management.

What Gastroenterologists Should Know About Microplastics and Nanoplastics.

Current Trends, Spatio-Temporal Dynamics of Microplastics Research and Global Public Health: A Scientometric Study.

Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics.

Omics insights in responses of bivalves exposed to plastic pollution.

Human Health Studies

Numerous Chemicals/Mixtures

Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants.

Exposure to Environmental Chemicals and Infertility Among US Reproductive-Aged Women

Developmental exposure to legacy environmental contaminants, medial temporal lobe volumes and spatial navigation memory in late adolescents.

Estimating the environmental burden of disease resulting from exposure to chemicals in European countries – potentials and challenges revealed in selected case studies.

Environmental Exposures and Canine Bladder Cancer: A Case Control Study Using Silicone Passive Samplers. [not human but close…]

Phenols/Phthalates/Parabens

Association Between Endocrine-Disrupting Chemicals Exposure and Attention-Deficit/Hyperactivity Disorder Symptoms in Children With Attention-Deficit/Hyperactivity Disorder.

Associations of phenols, parabens, and phthalates with biological aging: stratified analyses by chronological age and lifestyle in NHANES 2005-2010.

The associations between prenatal plastic phthalate exposure and lipid acylcarnitine levels in humans and mice.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Association between dietary intake estimated levels of PCDD/Fs and human sperm quality.

Application of three statistical approaches to explore effects of dietary intake of multiple persistent organic pollutants on ER-positive breast cancer risk in the French E3N cohort.

PFAS

Perfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study.

Per- and Polyfluoroalkyl Substances in Semen Associated with Repeated Measures of Semen Quality in Healthy Adult Men.

Per- and polyfluoroalkyl substances (PFAS) exposure is associated with radioiodine therapy resistance and dedifferentiation of differentiated thyroid cancer.

Sex specificity in associations between exposure to a mixture of per and poly-fluoroalkyl substances and anxiety among US adults.

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) from contaminated water and risk of childhood cancer in California, 2000-2015.

Prenatal Perfluoroalkyl Substance Exposure in Association with Global Histone Post-Translational Methylation in 2-Year-Old Children

Common infections in children aged 6 months to 7 years after high prenatal exposure to perfluoroalkyl substances from contaminated drinking water in Ronneby, Sweden.

Associations between per-and polyfluoroalkyl substances (PFAS) and county-level cancer incidence between 2016 and 2021 and incident cancer burden attributable to PFAS in drinking water in the United States.

Associations of maternal per- and polyfluoroalkyl substance plasma concentrations during pregnancy with offspring polycystic ovary syndrome and related characteristics in Project Viva.

Flame Retardants

Associations Between Brominated Flame Retardant Exposure and Depression in Adults: A Cross-Sectional Study.

Pesticides

Glyphosate exposure and GM seed rollout unequally reduced perinatal health.

Associations between environmental glyphosate exposure and glucose homeostasis indices in US general adults: a national population-based cross-sectional study.

Sex steroid hormones mediate the association between neonicotinoids and obesity among children and adolescents.

Neurobehavioral Performance in Preschool Children Exposed Postnatally to Organophosphates in Agricultural Regions, Northern Thailand

Metals/Metalloids

Association between urinary arsenic and hearing threshold shifts in adults in the United States, National Health and Nutrition Examination Survey, 2015-2016.

The association between blood metals and cardiovascular diseases: findings from National Health and Nutrition Examination Survey 2011-2020.

Effects of prenatal exposure to multiple heavy metals on infant neurodevelopment: a multi-statistical approach.

Pharmaceuticals/Personal Care Products

Hair Straightener Use in Relation to Prevalent and Incident Fibroids in the Sister Study with a Focus on Black Women and related Invited Perspective: Critical Needs for Advancing Beauty Justice.

Mental Disorders Among Offspring Prenatally Exposed to Systemic Glucocorticoids.

Miscellaneous

Prenatal polycyclic aromatic hydrocarbons exposure and child growth and adiposity: A longitudinal study.

Is Polyhexamethylene Guanidine and Oligo(2-(2-Ethoxy) Ethoxyethyl Guanidium Chloride Exposure Related to Gestational Diabetes?

Laboratory Studies

Numerous Chemicals/Mixtures

Developmental Programming: Sex-specific Effects of Prenatal Exposure to a Real-Life Mixture of Environmental Chemicals on Liver Function and Transcriptome in Sheep.

Impact of Endocrine Disruptors on Key Events of Hepatic Steatosis in HepG2 Cells.

In Vitro Toxicity of a DEHP and Cadmium Mixture on Sheep Cumulus-Oocyte Complexes.

BPA/Phenols

Bisphenol A alters JUN promoter methylation, impairing steroid metabolism in placental cells and linking to sub-representative phenotypes.

Preparation, characterization, and stability of selenium nanoparticles decorated with Mori Fructus polysaccharide and its protective effects in bisphenol A-induced Sertoli cells.

Oxidative Stress and Keap1-Nrf2 Pathway Involvement in Bisphenol A-Induced Liver Damage in Rats.

Effects of environmental bisphenol S exposure on male rat reproductive health and gut-blood-testicular axis integrity.

Protective effects of resveratrol and naringenin against nonylphenol-induced oxidative stress in rats.

Exploring the role of Bisphenol A in obesity-driven colorectal cancer progression: network toxicology and multi-organ pathology in animal models.

Maternal Bisphenol A Exposure Induces Hippocampal-Dependent Learning and Memory Deficits Through the PI3K/Akt/mTOR Pathway in Male Offspring Rats.

Bisphenol S induced endothelial dysfunction via mitochondrial pathway in the vascular endothelial cells, and detoxification effect of albumin binding.

Bisphenol S accelerates the progression of high fat diet-induced NAFLD by triggering ferroptosis via regulating HMGCS2.

Bisphenol A induces apoptosis and disrupts testosterone synthesis in TM3 cells via reactive oxygen species-mediated mitochondrial pathway and autophagic flux inhibition.

Critical Structures of Bisphenol Analogues on Embryonic Toxicity Identified by a Computational Approach.

Protective roles of herbal teas against the toxicity of Bisphenol A on morphometry of uterus and improving murine reproductive health.

Bisphenol A Exacerbates Colorectal Cancer Progression through Enhancing Ceramide Synthesis.

Phthalates

Exploring DiPP (Diisopentyl Phthalate) Neurotoxicity and the Detoxification Process in Zebrafish Larvae – A Silent Contaminant?

Single cell RNA-seq reveals that granulosa cells are a target of phthalate toxicity in the ovary.

Neurodevelopmental toxicity and mechanism of action of monoethylhexyl phthalate (MEHP) in the developing zebrafish (Danio rerio).

Developmental and neurotoxic effects of dimethyl phthalate on zebrafish embryos and larvae.

Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway.

A comprehensive analysis-based study of Di-(2-ethylhexyl) Phthalate (DEHP)-environmental explanation of bladder cancer progression.

Common Chemical Plasticizer Di(2-Ethhylhexyl) Phthalate Exposure Exacerbates Coxsackievirus B3 Infection.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Transcriptomic Analysis of Effects of Developmental PCB Exposure in the Hypothalamus of Female Rats.

Non-dioxin-like polychlorinated biphenyls (PCB 101, 153, and 180) and adipocyte lipid dysfunctions: involvement of glycerol and role of aquaglyceroporins in mature 3T3-L1 cells.

Molecular insights into developmental toxicity induced by PCB77 exposure on zebrafish via integrating transcriptomics with adverse outcome pathway.

PFAS

Perfluorooctanoic acid and its alternatives disrupt the osteogenesis and osteoclastogenesis balance: Evidence from the effects on cell differentiation process.

Mixed exposure to PFOA and PFOS induces oocyte apoptosis and subfertility in mice by activating the Hippo signaling pathway.

Unraveling the impact of PFOA toxicity on Zostera marina using a multi-omics approach: Insights from growth, physiological, transcriptomic, and metabolomic signatures.

Hexafluoropropylene Oxide Trimer Acid Is an Unsafe Substitute to Perfluorooctanoic Acid Due to Its Remarkable Liver Accumulation in Mice Disclosed by Comprehensive Toxicokinetic Models.

Role of hepatocyte-specific FOXO1 in hepatic glucolipid metabolic disorders induced by perfluorooctane sulfonate.

FAS biodegradation by Labrys portucalensis F11: Evidence of chain shortening and identification of metabolites of PFOS, 6:2 FTS, and 5:3 FTCA.

Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA.

Reproductive toxicity of perfluorobutane sulfonate in zebrafish (Danio rerio): Impacts on oxidative stress, hormone disruption and HPGL axis dysregulation.

Arginine Metabolism Reprogramming in Perfluorooctanoic Acid (PFOA)-Induced Liver Injury.

Developmental exposure to perfluorooctane sulfonate(PFOS) impairs the endometrial receptivity.

Per- and polyfluoroalkyl substances (PFASs) inhibit larval metamorphosis by impairing larval muscle degeneration in the mussel Mytilus coruscus.

Photochemical Formation of Trifluoroacetic Acid: Mechanistic Insights into a Fluoxetine-Related Aryl-CF₃ Compound.

PFOS-Induced Perturbations in Trophoblast Functions through the Oip5os1/miR-155/Rnd3 Axis in PE.

Flame Retardants

Tris(2-chloroethyl) Phosphate Leads to Unbalanced Circulating Erythrocyte in Mice by Activating both Medullary and Extramedullary Erythropoiesis.

Toxicity of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) on Oligodendrocytes During Embryonic Zebrafish Development.

Melatonin attenuates BDE-209-caused spatial memory deficits in juvenile rats through NMDAR-CaMKⅡγ-mediated synapse-to-nucleus signaling.

Tetrabromobisphenol A, but not bisphenol A, disrupts plasma membrane homeostasis in myeloid cell models – A novel threat from an established persistent organic pollutant.

Pesticides

Early life exposure to deltamethrin impairs synaptic function by altering the brain derived extracellular vesicle proteome.

Comparison of oxidative stress status in the kidney tissue of male rats treated with paraquat and nanoparaquat.

Toxicological Impact of Chronic Chlorpyrifos Exposure: DNA Damage and Epigenetic Alterations Induces Neoplastic Transformation of Liver Cells.

The hygienic insecticide dimefluthrin induced neurodevelopmental deficits and behavioral disorders in zebrafish (Danio rerio) larvae.

Protective effects of Lavandula stoechas and Thymus numidicus essential oils against deltamethrin-induced hematological and biochemical toxicity in female rabbits.

From Cell to Organ: Exploring the Toxicological Correlation of Organophosphorus Compounds in Living System.

Glyphosate-Based Herbicide Stress During Pregnancy Impairs Intestinal Development in Newborn Piglets by Modifying DNA Methylation.

Metals/Metalloids

Evidence linking cadmium and/or lead exposure to immunomodulatory effects in mammals based upon an adverse outcome pathways approach, and research perspectives.

Arsenic Exposure Triggers Nonalcoholic Fatty Liver Disease through Repressing S–Adenosylmethionine-Dependent Histone Methylation in Rats.

Sodium arsenite induces islets β-cells apoptosis and dysfunction via SET-Rac1-mediated cytoskeleton disturbance.

Predictive model in silicon and pathogenicity mechanism of metabolic syndrome: Impacts of heavy metal exposure.

Active Vitamin D Ameliorates Arsenite-Induced Thyroid Dysfunction in Sprague-Dawley Rats by Inhibiting the Toll-like Receptor 4/NF-KappaB-Mediated Inflammatory Response

Microplastics/Nanomaterials

PD-like pathogenesis induced by intestinal exposure to microplastics: An in vivo study of animal models to a public health survey.

Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota.

Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring.

Teratological, neurochemical and histomorphic changes in the limbic areas of F1 mice progeny due to co-parental polystyrene nanoplastic exposure.

Nanoplastics induces arrhythmia in human stem-cells derived cardiomyocytes.

Microplastics Exposure Aggravates Synovitis and Pyroptosis in SLE by Activating NF-κB and NRF2/KEAP1 Signaling.

Co-exposure to polystyrene nanoplastics and F-53B induces vascular endothelial cell pyroptosis through the NF-κB/NLRP3 pathway.

Influence of selected dosages of plastic microparticles on the porcine fecal microbiome.

Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice.

Maternal Exposure to Polystyrene Nanoplastics Disrupts Spermatogenesis in Mouse Offspring by Inducing Prdm14 Overexpression in Undifferentiated Spermatogonia.

Amplification of benzo[a]pyrene toxicity persistence in earthworms by polystyrene nanoplastics: From organismal health to molecular responses.

Unseen Threats: The Long-term Impact of PET-Microplastics on Development of Male Reproductive Over a Lifetime.

Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage.

Miscellaneous

Exposure to 6PPD-Q induces dysfunctions of ovarian granulosa cells: Its potential role in PCOS.

Long-Term Exposure to Tire-Derived 6-PPD Quinone Causes Neurotoxicity and Neuroinflammation via Inhibition of HTR2A in C57BL/6 Mice.

Acute and Subchronic Toxicity of 6PPD-Quinone to Early Life Stage Lake Trout (Salvelinus namaycush).

Toxicity and intergenerational accumulation effect of tire wear particles and their leachate on Brachionus plicatilis.

Developmental Toxicity of Disinfection Byproducts in F344 Rats: Effects on Pregnancy Maintenance and Eye Development.

Exposure/Environment Studies

Numerous Chemicals/Mixtures

Participant perspectives related to individual chemical exposure report-back approaches in three environmental health studies.

Awareness and Knowledge of Endocrine-Disrupting Chemicals Among Pregnant Women and New Mothers: A Cross-Sectional Survey Study.

The dead can talk: Investigating trace element and organic pollutant exposure in mammalian roadkill under contrasting habitats.

BPA/Phenols

Release of Bisphenol A and Other Volatile Chemicals from New Epoxy Drinking Water Pipe Liners: The Role of Manufacturing Conditions.

Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula.

Phthalates

Temporal and spatial variations of urinary phthalate metabolites for adults in China (2005 – 2020): A synthesis of biomonitoring data.

Phthalates in the environment of China: A scoping review of distribution, anthropogenic impact, and degradation based on meta-analysis.

Assessing the effect of sunlight exposure and reuse of polyethylene terephthalate bottles on phthalate migration.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Temporal trends and spatial variations of chlorinated paraffins and olefins in sewage sludge from eight Swiss wastewater treatment plants from 1993 to 2020.

PFAS

High organofluorine concentrations in municipal wastewater affect downstream drinking water supplies for millions of Americans.

Assessment of modeled serum per- and polyfluoroalkyl substances concentrations from exposure estimates for pregnant women in the general population in comparison to previously measured serum concentrations.

Socioeconomic Disparities in Exposures to PFAS and Other Unregulated Industrial Drinking Water Contaminants in US Public Water Systems.

Association Between Serum Levels of Perfluoroalkyl and Polyfluoroalkyl Substances and Dental Floss Use: The Double-Edged Sword of Dental Floss Use-A Cross-Sectional Study.

Unveiling per- and polyfluoroalkyl substances contamination in e-cigarette refill liquids: A comprehensive analytical assessment.

PFAS contamination in tap water: Target and suspect screening of zwitterionic, cationic, and anionic species across Canada and beyond.

Tissue histology and depuration of per- and polyfluoroalkyl substances (PFAS) from dairy cattle with lifetime exposures to PFAS-contaminated drinking water and feed.

Comparative analysis of PFASs concentrations in fur, muscle, and liver of wild roe deer as biomonitoring matrices.

Sources and Pathways of PFAS Occurrence in Water Sources: Relative Contribution of Land-Applied Biosolids in an Agricultural Dominated Watershed.

Historical reconstruction of PFAS discharge into the Cooum River – before and after the great Chennai flood in 2015.

Nontarget Analysis and Characterization of a Group of Abundant Polyfluoroalkyl Substances─Fluorinated Benzoylurea Pesticides and Their Analogues and Transformation Products in Fish by LC-HRMS and Chemical Species-Specific Algorithms.

Flame Retardants

Occurrence of PBDEs in car and airplane dust in Poland – exposure assessment and health risk characterization for selected age ranges.

Global human exposure of atmospheric polybrominated diphenyl ethers: Variation patterns of exposure pathways and phase contributions.

Occurrence and bioaccumulation of organophosphate flame retardants in high-altitude regions: A comprehensive field survey in Qinghai Province, China.

Emerging and legacy organophosphate flame retardants in the tropical estuarine food web: Do they exhibit similar bioaccumulation patterns, trophic partitioning and dietary exposure?

Metals/Metalloids

Exposure to Lead, Cadmium, Mercury and Arsenic Among Asian and Non-Asian Children and Adolescents in the United States: NHANES 2015-2018.

Microplastics/Nanomaterials

Microplastic Particles Detected in Fetal Cord Blood, Placenta, and Meconium: A Pilot Study of Nine Mother-Infant Pairs in South China

Unveiling the Truth of Interactions between Microplastics and Per- and Polyfluoroalkyl Substances (PFASs) in Wastewater Treatment Plants: Microplastics as a Carrier of PFASs and Beyond.

Detection of microplastics in pterygium tissue: Implications for environmental hazards.

From the ocean to our kitchen table: anthropogenic particles in the edible tissue of U.S. West Coast seafood species.

Miscellaneous

Occurrence and potential risk of steroid hormones in selected surface water and wastewater treatment plants in western Kenya.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Industry-funded articles are included without notation. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me and ask to join the EDC Science Weekly group EDC_research@googlegroups.com. There are searchable archives. Compiled by Sarah Howard of Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

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EHN EHN

Webinar: Ultrashort-chain PFAS: the global threat of trifluoroacetic acid
by Sarah Howard on January 16, 2025 at 3:35 pm
This Feb. 19, 2025 webinar features Dr. Hans Peter Arp discussing TFA, a degradation product of many refrigerants and a widespread contaminant in the environment. Shorter-chain PFAS have been assumed to be less hazardous than longer-chain PFAS, but widespread exposures have not been taken into account in making this assessment. Sponsored by the EDC Strategies Partnership.
Webinar: PFAS and cancer
by Sarah Howard on January 13, 2025 at 4:53 pm
This Jan. 23, 2025 webinar is sponsored by the Health and Environment Alliance and Association of European Cancer Leagues. It will explore links between PFAS and cancer in the context of the International Agency for Research on Cancer (IARC) evaluation and relevant epidemiological data, and features Dr. Tony Fletcher, an environmental epidemiologist and Associate Professor at the London School of Hygiene & Tropical Medicine.
Webinar: Product data for public health: Clearya case studies
by Sarah Howard on January 13, 2025 at 2:55 pm
A variety of tools have been created for collecting consumer product data and making it available for research. This Jan. 30, 2025 webinar will explore one such product. Sponsored by the Collaborative for Health and Environment (CHE).

EHN EHN

Wastewater treatment plants fail to remove most toxic PFAS from drinking water sources
by Katherine McMahon,Sarah Howard on January 17, 2025 at 5:14 pm
Wastewater treatment facilities with technology similar to the plants that serve 70% of the US population are ill-equipped to address contamination from organofluorine chemicals, a class of chemicals that include toxic PFAS, according to recent findings published in the Proceedings of the National Academy of Sciences. “The US Food and Drug Administration’s drug approval process does not consider the environmental persistence and secondary human and ecological exposures to pharmaceuticals….The potential public health consequences of ubiquitous low-level exposures to these compounds require urgent consideration.”
Exposure to common household chemicals linked to bladder cancer in dogs
by Katherine McMahon,Sarah Howard on January 16, 2025 at 6:53 pm
In a recent study published in Environmental Science & Technology, researchers compared levels of chemical exposures between healthy dogs and dogs displaying early signs of bladder cancer. “Our household pets share our daily domestic environment and thus offer opportunities for consideration as sentinel species for exposure related concerns.”
Exposure to BPA during pregnancy disrupts uterine development, increasing preeclampsia risk
by EHN Curators on January 16, 2025 at 5:03 pm
Recent research using mouse models shows that bisphenol A (BPA), a common chemical in plastics, impairs uterine development during pregnancy and increases the risk of preeclampsia, a life-threatening condition. Pamela Ferdinand reports for U.S. Right To Know.

EHN EHN

EU facing pressure over PFAS ban as chemical industry ramps up lobbying
by EHN Curators on January 16, 2025 at 12:37 pm
A cross-European investigation has revealed how the chemical industry is intensifying efforts to influence the EU’s proposed ban on PFAS chemicals, raising concerns about regulatory delays and environmental harm. Robert Hodgson reports for Euronews.
Industry pushback intensifies against EU proposal to regulate all PFAS chemicals
by EHN Curators on January 15, 2025 at 12:15 pm
A cross-border investigation reveals that industry lobbying efforts, including funded research and exaggerated economic claims, are slowing attempts to regulate PFAS chemicals linked to environmental contamination and health concerns. Rachel Salvidge and Leana Hosea report for The Guardian.
Chemical regulations leave children vulnerable to harmful exposure
by EHN Curators on January 10, 2025 at 7:01 pm
A New England Journal of Medicine article warns that weak U.S. chemical regulations have failed to protect children from exposure to harmful synthetic chemicals, contributing to rising rates of childhood cancers, asthma and obesity. Jim Morris reports for Public Health Watch.