1999 First Environment and Hormone (e-hormone) conference held at Tulane, organized by Dr. John McLachlan.
No threshold or safe levels: This study showed that there was no threshold when an estrogen was added to a biological system that already had an above threshold level of estradiol, falsifying the assumption by the FDA and EPA that all non-genotoxic chemicals had a threshold below which no adverse effects occurred. The threshold assumption has still not been abandoned by regulatory agencies:
Sheehan DM, Willingham E, Gaylor D, Bergeron JM, Crews D. No threshold dose for estradiol-induced sex reversal of turtle embryos: how little is too much? Environ Health Perspect. 1999 Feb;107(2):155-9.
Hormonally Active Agents in the Environment report by the National Academies.
Community Strategy for Endocrine Disrupters report by the European Commission.
The Yokohama International Workshop on the effects of Endocrine Disruptors in Living Things resulted in The Yokohama Consensus Statement.