EDC Science Weekly, Aug. 22 – Sept. 5, 2024

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed for the past two weeks, so a little longer this time.

Contents: Events, Methods/Tools/Screening, Commentaries, Reviews/Meta-Analyses, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Highlights:

Science evolves but outdated testing in the US delay protection to human health;
The dose disrupts the pathway: application of Paracelsus principle to mechanistic toxicology;
European partnership on the assessment of risks from chemicals (PARC): focus on new approach methodologies (NAMs);
Should pregnant women consume probiotics to combat endocrine-disrupting chemical-induced health risks to their unborn offspring?

We are now accepting applications for the Lou Guillette, Jr Outstanding Young Investigator Award, due Sept. 30!

Science summaries and highlights

Events

Sept. 18 webinar: Artificial Turf: Research on Plastic Pollution, PFAS, and Health Concerns [CHE]

Sept. 23-24: Plastics and Human Health Symposium [NYU Langone Health Center for the Investigation of Environmental Hazards]

Sept. 25: Public Meeting on the Development of an Enhanced Systematic Process for FDA’s Post-Market Assessment of Chemicals in Food [US FDA]

Sept. 30 and Oct. 1: Webinar on Next Round of Chemical Substances Being Considered for Prioritization Under TSCA [US EPA]

Oct. 7-8: Workshop on Advancing Quantitative Analysis in Human Health Assessments through Probabilistic Methods [US EPA]

Oct. 10: Children’s Environmental Health Day [Children’s Environmental Health Network]

Oct. 14-16: 8th Annual meeting of the U.S. DOHaD Society: exploring translational DOHaD science: from cells to communities in Chapel Hill, NC.

Oct. 28: Swiss Symposium on Endocrine Disrupting Chemicals [Food Packaging Forum and ETH Zurich]

Nov. 5-6 conference: State of the science on development and use of NAMs for chemical safety testing [U.S. EPA]

More events

Methods/Tools/Screening

The dose disrupts the pathway: application of Paracelsus principle to mechanistic toxicology

Seminar: Functional Exposomics and Mechanisms of Toxicity-Insights from Model Systems and NAMs.

Exposure range matters: considering non-linear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes.

Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin. [PFAS]

The Role of Mass Spectrometry in Protecting Public Health and the Environment from Synthetic Chemicals.

Advancing Ecotoxicological Studies: Utilizing New Approach Methodologies to Enable Cross-Species Extrapolation and Reduce Avian Testing.

Integration of Advanced Large Language Models into the Construction of Adverse Outcome Pathways: Opportunities and Challenges.

Incorporating Tissue-Specific Gene Expression Data to Improve Chemical-Disease Inference of in Silico Toxicogenomics Methods.

Machine learning for environmental justice: Dissecting an algorithmic approach to predict drinking water quality in California.

Prediction of Endocrine-Disrupting Chemicals Related to Estrogen, Androgen, and Thyroid Hormone (EAT) Modalities Using Transcriptomics Data and Machine Learning.

AOP Report: An Upstream Network for Reduced Androgen Signaling Leading to Altered Gene Expression of Androgen Receptor-Responsive Genes in Target Tissues.

Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis.

Progress in toxicogenomics to protect human health.

An innovative mixture sampling strategy with uniform design: Application to global sensitivity analysis of mixture toxicity.

There is no need for overnight fasting of rats in regulatory toxicology studies.

Metabolic disrupting chemicals in the intestine: the need for biologically relevant models: Zebrafish: what can we learn from this small environment-sensitive fish?

Leveraging New Approach Methodologies: Ecotoxicological Modelling of Endocrine Disrupting Chemicals to Danio rerio through Machine Learning and Toxicity Studies.

Advancing high quality longitudinal data collection: Implications for the HEALthy Brain and Child Development (HBCD) Study design and recruitment.

Commentaries

Science evolves but outdated testing and static risk management in the US delay protection to human health.

Climate Actions, Persistent Pollutants, and Human Health: A Call for Integrated Assessments.

Understanding PFAS: Occurrence, Fate, Removal, and Effects. [Intro to a special issue in Toxics]

Transforming toxicology one cell at a time: A special issue on the application of scRNA-seq to the study of environmental response

Editorial: European partnership on the assessment of risks from chemicals (PARC): focus on new approach methodologies (NAMs) in risk assessment.

Endogenous hormones matters in evaluation of endocrine disruptive effects mediated by nuclear receptors.

The unfairness of fairness creams: unveiling the toxic impact on kidneys of mercury in beauty products.

Neurotox Screen? Zebrafish Study Points to PFOS Early-Life Exposure Effects. [Science Selection in EHP]

Reviews/Meta-Analyses

Numerous Chemicals/Mixtures

Should Pregnant Women Consume Probiotics to Combat Endocrine-Disrupting Chemical-Induced Health Risks to Their Unborn Offspring?

Endocrine Disrupting Chemicals, Reproductive Aging, and Menopause: A Review.

Canine on the Couch: The New Canary in the Coal Mine for Environmental Health Research.

An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.

Main Factors Influencing the Perceived Health Risk of Endocrine-Disrupting Chemicals: A Systematic Literature Review.

Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms.

Environmental endocrine disruptor-induced mitochondrial dysfunction: a potential mechanism underlying diabetes and its complications.

Environmental pollutants as risk factors for autism spectrum disorders: a systematic review and meta-analysis of cohort studies.

Endocrine disrupting chemicals and obesity prevention: scoping review.

BPA/Phenols/Phthalates

Adverse outcomes of the newly emerging bisphenol A substitutes.

Biological significance of long-term bisphenol A release in the saliva of patients wearing orthodontic appliances: A systematic review and meta-analysis.

Evaluating Phthalates and Bisphenol in Foods: Risks for Precocious Puberty and Early-Onset Obesity

Association between the Exposure to Phthalates and the Risk of Endometriosis: An Updated Review

Association between phthalate exposure and risk of allergic rhinitis in children: A systematic review and meta-analysis.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

How Agent Orange impacts prostate cancer risk, pathology, and treatment outcomes.

PFAS

Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts.

Asthma and Decreased Lung Function in Children Exposed to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs): An Updated Meta-Analysis Unveiling Research Gaps.

Per- and Polyfluoroalkyl Substances (PFASs) and Their Potential Effects on Female Reproductive Diseases.

Per- and polyfluoroalkyl substances (PFAS) and Hypertensive disorders of Pregnancy- Integration of Epidemiological and Mechanistic Evidence.

Pesticides

Potential Role of Glyphosate, Glyphosate-Based Herbicides, and AMPA in Breast Cancer Development: A Review of Human and Human Cell-Based Studies

Dietary Exposure to Pesticide and Veterinary Drug Residues and Their Effects on Human Fertility and Embryo Development: A Global Overview.

Effects of Insecticide and Herbicides on Thyroid Disturbances in Zebrafish.

Respiratory system: Highly exposed yet under-reported organ in pyrethrin and pyrethroid toxicity.

Metals/Metalloids

Heavy metals exposure and Alzheimer’s disease: Underlying mechanisms and advancing therapeutic approaches.

Microplastics/Nanomaterials

Detection of microplastics in human tissues and organs: A scoping review.

Mixtures of Micro and Nanoplastics and Contaminants of Emerging Concern in Environment: What We Know about Their Toxicological Effects.

The Impact of Maternal Nanoplastic and Microplastic Particle Exposure on Mammal’s Offspring.

Plastic induced urinary tract disease and dysfunction: a scoping review.

Air Pollution

Effect of air pollutants particulate matter (PM_2.5, PM₁₀), sulfur dioxide (SO₂) and ozone (O₃) on cognitive health.

Pharmaceuticals/Personal Care Products

Tiny Pills, Big Impacts: A systematic review on the endocrine disrupting effects of pediatric pharmaceuticals.

Are natural estrogens used in contraception at lower risk of venous thromboembolism than synthetic ones? A systematic literature review and meta-analysis.

Miscellaneous

Comparing environmental fate and ecotoxicity of conventional and biodegradable plastics: A critical review.

The Environment, Lifestyles and Climate Change: The Many Nongenetic Contributors to The Long and Winding Road to Autoimmune Diseases.

Human Health Studies

Numerous Chemicals/Mixtures

Perinatal Exposure to Phenols and Poly- and Perfluoroalkyl Substances and Gut Microbiota in One-Year-Old Children.

Sex-Specific Associations between Prenatal Exposure to Bisphenols and Phthalates and Infant Epigenetic Age Acceleration.

Co-exposure to parabens, bisphenol A, and triclosan and the associations with dyslipidemia in Chinese older adults: the mediation effect of oxidative stress.

Mixtures of Urinary Phenol and Phthalate Metabolite Concentrations in Relation to Serum Lipid Levels among Pregnant Women: Results from the EARTH Study.

Persistent endocrine-disrupting chemicals and incident uterine leiomyomata: A mixtures analysis.

Associations between Structural Racism, Environmental Burden, and Cancer Rates: An Ecological Study of US Counties.

Potential mechanisms and modifications of dietary antioxidants on the associations between co-exposure to plastic additives and diabetes.

BPA/Phenols

Association between Bisphenol A and Prostate-Specific Antigen (PSA) among U.S. Older Males: National Health and Nutrition Examination Survey (NHANES), 2003-2012.

Influence of Genetic Polymorphisms on Cognitive Function According to Dietary Exposure to Bisphenols in a Sample of Spanish Schoolchildren.

Association of phenol exposure during pregnancy and asthma development in children: The Japan Environment and Children’s Study.

Phthalates

Maternal symptoms of depression and anxiety as modifiers of the relationship between prenatal phthalate exposure and infant neurodevelopment in the Atlanta African American maternal-child cohort.

Association of phthalates exposure and sex steroid hormones with late-onset preeclampsia: a case-control study.

Gene-environment interaction between phthalate exposure and pubertal genetic polymorphisms on blood pressure variability in children: Exploring the moderating effects of lifestyle behaviours.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Prospective study on the joint effect of persistent organic pollutants and glucose metabolism on chronic kidney disease: Modifying effects of lifestyle interventions.

Organochlorine pesticides and their markers of exposure in serum and urine of children from a nodding syndrome hotspot in Northern Uganda, East Africa.

High Expression of AhR and Environmental Pollution as AhR-Linked Ligands Impact on Oncogenic Signaling Pathways in Western Patients with Gastric Cancer-A Pilot Study

PFAS

Association between exposure to perfluoroalkyl substances (PFAS) and endometriosis in the ENDEA case-control study.

Prenatal Exposure to Per- and Polyfluoroalkyl Substances and ASD-Related Symptoms in Early Childhood: Mediation Role of Steroids.

Association Between Prenatal Exposure to Per- and Poly-Fluoroalkyl Substances From Electronic Waste Disassembly Areas and Steroid Hormones in Human Milk Samples.

Exposure to per- and polyfluoroalkyl substances and age-related macular degeneration in U.S. middle-aged and older adults.

Perfluoroalkyl and Polyfluoroalkyl Substances in Relation to the Participant-Reported Total Pregnancy and Live Birth Numbers among Reproductive-Aged Women in the United States.

Dissect the association between per- and polyfluoroalkyl substances (PFAS) and kidney function from the perspective of lipid molecules.

Isomer of per- and polyfluoroalkyl substances and red blood cell indices in adults: The Isomers of C8 Health Project in China.

Perfluoroalkyl substances exposure and the risk of breast cancer: A nested case-control study in Jinchang Cohort.

Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2.

Gestational PFAS exposure and newborn size: The modifying effect of cord blood fatty acids.

Association between Serum 6:2 Chlorinated Polyfluorinated Ether Sulfonate Concentrations and Lung Cancer.

Flame Retardants

Identification of serum metabolites associated with polybrominated diphenyl ethers (PBDEs) exposure in papillary thyroid carcinoma: a case-control study.

Association between brominated flame retardants (BFRs) and periodontitis: Results from a large population-based study.

Pesticides

Associations between Glyphosate Exposure and Glycemic Disorders: A Focus on the Modifying Effect of Sex Hormones.

Association of Urinary Glyphosate with All-Cause Mortality and Cardiovascular Mortality among Adults in NHANES 2013-2018: Role of Alkaline Phosphatase.

Association of urinary glyphosate levels with iron homeostasis among a representative sample of US adults: NHANES 2013-2018.

Exposure to agricultural pesticides and wheezing among 5-12-year-old children in the Imperial Valley, CA, USA.

Exposure to household pesticides and Parkinson’s disease in the Parkinson’s Progression Markers Initiative cohort.

Metals/Metalloids

Arsenic exposure and measures of glucose tolerance in Bangladeshi adults: A cross-sectional study.

Association between gestational arsenic exposure and infant physical development: a prospective cohort study.

Serum and urinary cadmium and zinc profiles in breast cancer patients and their association with estrogen and HER-2 receptors, and redox status.

Associations between Non-Essential Trace Elements in Women’s Biofluids and IVF Outcomes in Euploid Single-Embryo Transfer Cycles.

Association between Liver and Kidney Function and Birth Outcomes in Pregnant Surinamese Women Exposed to Mercury and Lead in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study.

Early Postnatal and Concurrent Exposure to Metals and Neurobehavioral Outcomes at 5 Years: Associations with Individual Environmental Exposures and Mixtures.

Associations of urinary heavy metals with age at menarche, age at menopause, and reproductive lifespan: A cross-sectional study in U.S. women.

Microplastics/Nanomaterials

Microplastics are associated with elevated atherosclerotic risk and increased vascular complexity in acute coronary syndrome patients.

Consumption of Bottled Water and Chronic Diseases: A Nationwide Cross-Sectional Study

Air Pollution

Extreme temperatures, PM_2.5 and trajectories of impaired thyroid hormone sensitivity: A longitudinal study of patients with schizophrenia.

Multidimensional structural racism and estimated cancer risk from traffic-related air pollution.

Carcinogenic industrial air pollution and postmenopausal breast cancer risk in the National Institutes of Health AARP Diet and Health Study.

Exposure to Low-Level Air Pollution and Hyperglycemia Markers during Pregnancy: A Repeated Measure Analysis.

The relationship between air pollution and the occurrence of hypertensive disorders of pregnancy: Evidence from a study in Wuhan, China.

Miscellaneous

Role of Propolis Consumption on Endocrine Disruption in Children.

Laboratory Studies

Numerous Chemicals/Mixtures

Preconception and/or preimplantation exposure to a mixture of environmental contaminants altered fetoplacental development and placental function in a rabbit model.

Multiomics Screening Identified CpG Sites and Genes That Mediate the Impact of Exposure to Environmental Chemicals on Cardiometabolic Traits.

Prenatal Exposure to Bisphenol A and/or Diethylhexyl Phthalate Impacts Brain Monoamine Levels in Rat Offspring.

BPA/Phenols

Heterogeneity effects of bisphenol A and its substitute, fluorene-9-bisphenol, on intestinal homeostasis.

A Potential Neurotoxic Mechanism: Bisphenol S-Induced Inhibition of Glucose Transporter 1 Leads to ATP Excitotoxicity in the Zebrafish Brain.

Prenatal low-dose Bisphenol A exposure impacts cortical development via cAMP-PKA-CREB pathway in offspring.

The Toxic Effects and Mechanisms of Maternal Exposure to Bisphenol F During Gestation and Lactation on Lungs in Female Offspring Mice.

Evaluation of Bisphenol S (BPS) Toxicity on the Reproductive system of Channa striatus: Insights for Environmental Risk Assessment.

Unraveling the role of bisphenol A in osteosarcoma biology: insights into prognosis and immune microenvironment modulation.

Exploring the interplay between bisphenol A exposure, the immune microenvironment and hepatocellular carcinoma progression.

The possible protective effect of ginger extract on toxic changes induced by bisphenol A on the thyroid gland of adult male albino rats: light and electron microscopic study.

Geraniol alleviates liver injury induced by bisphenol A via modulating NLRP3/caspase-1 pathway and gut microbiota in mice model.

Green Tea Diet Can Effectively Antagonize the Toxicity Induced by Environmental-Related Concentrations of BPA: An Implication from In Vivo and In Silico Studies.

Bisphenol C Induces Cardiac Developmental Defects by Disrupting m⁶A Homeostasis.

Bisphenol A-induced ovarian damage countered by luteolin: Experiments in in vitro CHO cells and in vivo PCOS phenotype zebrafish.

High-throughput transcriptomics toxicity assessment of eleven data-poor bisphenol A alternatives

Phthalates

Mono-(2-ethylhexyl) phthalate induces trophoblast hypoxia and mitochondrial dysfunction through HIF-1α-miR-210-3p axis in HTR-8/SVneo cell line.

Confirmation of Di(2-ethylhexyl) phthalate-induced micronuclei by repeated dose liver micronucleus assay: focus on evaluation of liver micronucleus assay in young rats.

Elucidating the mechanism of plasticizers inducing breast cancer through network toxicology and molecular docking analysis.

Exposure to endocrine disruptor DEHP promotes the progression and radiotherapy resistance of pancreatic cancer cells by increasing BMI1 expression and properties of cancer stem cells.

Intergenerational metabolism-disrupting effects of maternal exposure to plasticizer acetyl tributyl citrate (ATBC).

Parabens/Triclosan/Antimicrobials

Understanding the molecular pathway of triclosan-induced ADHD-like behaviour: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Polychlorinated Biphenyls (PCBS)-induced oxidative stress and inflammation in human thyrocytes: involvement of AhR and NRF-2/HO-1 pathway.

Perinatal exposure to Aroclor 1254 disrupts thyrotropin-releasing hormone mRNA expression in the paraventricular nucleus of male and female rats.

Daily exposure to chlordecone, an organochlorine pesticide, increases cardiac fibrosis and atrial fibrillation vulnerability.

Adaptation of Brown Adipose Tissue in Response to Chronic Exposure to the Environmental Pollutant 1,1-Dichloro-2,2-bis(p-chlorophenyl) Ethylene (DDE) and/or a High-Fat Diet in Male Wistar Rats.

Medium-Chain Chlorinated Paraffins Trigger Thyroid Hormone Synthesis and Interfere with Mitochondrial Function in the Thyroid Gland.

PFAS

Exposure of Ldlr–/– Mice to a PFAS Mixture and Outcomes Related to Circulating Lipids, Bile Acid Excretion, and the Intestinal Transporter ASBT

Neurotoxicity and intestinal microbiota dysbiosis induced by per- and polyfluoroalkyl substances in crucian carp (Carassius auratus).

Critical new insights into the interactions of hexafluoropropylene oxide-dimer acid (GenX or HFPO-DA) with albumin at molecular and cellular levels.

PFOS and PFOSA induce oxidative stress-mediated cardiac defects in zebrafish via PPARγ and AHR pathways, respectively.

The phosphorylation of Smad3 by CaMKIIγ leads to the hepatocyte pyroptosis under perfluorooctane sulfonate exposure.

Transcriptomics-based analysis reveals hexafluoropropylene oxide trimer acid (HFPO-TA) induced kidney damage and lipid metabolism disorders in SD rats.

Interaction of Per- and Polyfluoroalkyl Substances with Estrogen Receptors in Rainbow Trout (Oncorhynchus mykiss): An In Silico Investigation.

Perfluorooctane sulfonate causes damage to L-02 cells via Wnt/β-catenin signal path and endoplasmic reticulum stress pathway.

Transport of perfluoroalkyl substances across human induced pluripotent stem cell-derived intestinal epithelial cells in comparison with primary human intestinal epithelial cells and Caco-2 cells.

Impact of the novel chlorinated polyfluorinated ether sulfonate, F-53B, on gill structure and reproductive toxicity in zebrafish.

Exploring maternal and developmental toxicity of perfluoroalkyl ether acids PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics.

Chronic Toxicity of Per- and Polyfluoroalkyl Substance-Free Firefighting Foams to Aquatic Organisms.

Flame Retardants

Effects of novel flame retardants tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and triphenyl phosphate (TPhP) on function and homeostasis in human and rat pancreatic beta-cell lines.

Developmental toxicity of an emerging organophosphate Ester Bis-(2-ethylhexyl)-phenyl phosphate on embryonic zebrafish: Comparison to 2-ethylhexyl diphenyl phosphate.

Maternal Exposure to Low-Dose BDE-47 Induced Weight Gain and Impaired Insulin Sensitivity in the Offspring

Pesticides

Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development-potential mediation by glucocorticoid receptor.

Perinatal Exposure to Glyphosate or a Commercial Formulation Alters Uterine Mechanistic Pathways Associated with Implantation Failure in Rats.

Effects of glyphosate on neurotoxicity, oxidative stress and immune suppression in red swamp crayfish, Procambarus Clarkii.

Sensitivity Variations in Developmental Toxicity of Imidacloprid to Zebrafish Embryos at Different Neurodevelopmental Stages.

Pyrethroids and reproductive function: some endocrine disrupting perspectives from molecular simulations.

Vitamin E alleviates glyphosate-based herbicide-induced progesterone secretion inhibition and oxidative stress increase in chicken primary granulosa cells.

Melatonin attenuates affective disorders and cognitive deficits induced by perinatal exposure to a glyphosate-based herbicide via antioxidant pathway in adult male and female rats.

Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats.

Metals/Metalloids

Cadmium activation of wild-type and constitutively active estrogen receptor alpha.

Cadmium exposure induces skeletal muscle insulin resistance through the reactive oxygen species-mediated PINK1/Parkin pathway.

Epicatechin ameliorates glucose intolerance and hepatotoxicity in sodium arsenite-treated mice.

Co-exposure to multiple heavy metals and metalloid induces dose dependent modulation in antioxidative, inflammatory, DNA damage and apoptic pathways progressing to renal dysfunction in mice.

Microplastics/Nanomaterials

Eco-toxicity assessment of polypropylene microplastics in juvenile zebrafish (Danio rerio).

Polystyrene nanoplastics alter intestinal toxicity of 2,4-DTBP in a sex-dependent manner in zebrafish (Danio rerio).

Integrated transcriptomics and metabolomics reveal the mechanism of polystyrene nanoplastics toxicity to mice.

Impacts of Environmental Concentrations of Nanoplastics on Zebrafish Neurobehavior and Reproductive Toxicity.

Chronic Polystyrene Microplastic Exposure Reduces Testosterone Levels in Mice through Mitochondrial Oxidative Stress and BAX/BCL2-Mediated Apoptosis.

Toxicity to the Male Reproductive System after Exposure to Polystyrene Nanoplastics: A Macrogenomic and Metabolomic Analysis.

Impact of polyethylene nanoplastics on human intestinal cells.

The Potential Mechanisms Involved in the Disruption of Spermatogenesis in Mice by Nanoplastics and Microplastics

Long-Term Exposure to Polystyrene Microspheres and High-Fat Diet-Induced Obesity in Mice: Evaluating a Role for Microbiota Dysbiosis.

Air Pollution

Chronic maternal exposure to low-dose PM_2.5 impacts cognitive outcomes in a sex-dependent manner.

Miscellaneous

Emerging investigator series: in-depth chemical profiling of tire and artificial turf crumb rubber: aging, transformation products, and transport pathways.

Exposure/Environment Studies

Numerous Chemicals/Mixtures

A randomized controlled trial of a housing intervention to reduce endocrine disrupting chemical exposures in children.

Wristband Personal Passive Samplers and Suspect Screening Methods Highlight Gender Disparities in Chemical Exposures.

Chemical and non-chemical stressors in a postpartum cohort through wristband and self report data: Links between increased chemical burden, economic, and racial stress.

Silicone tags as an effective method of monitoring environmental contaminant exposures in a geographically diverse sample of dogs from the Dog Aging Project.

Comprehensive survey on the use of plastic additives in toy products used in Japan.

Do dietary exposures to multi-class endocrine disrupting chemicals translate into health risks for Gangetic dolphins? An assessment and way forward.

Occupational exposure of nail technicians to industrial chemicals: A pilot study.

Organic food and internal exposure to pollutants among Flemish adolescents.

Female-Biased Sex Ratios and Delayed Puberty in Two Fish Species with Different Ecologies in an Anthropogenically Affected Urban Lake.

Occurrence, distribution, and fate evaluation of endocrine disrupting compounds in three wastewater treatment plants with different treatment technologies in Türkiye.

BPA/Phenols

Investigation of bisphenol S (BPS) in packaged fish, meat, cheese, and price labels on their corresponding packages.

Determination of the occurrence of and exposure to bisphenol A and its analogues in carbonated beverages and canned tuna using liquid chromatography - tandem mass spectrometry.

Phthalates

Impact of Skin Care Products on Phthalates and Phthalate Replacements in Children: the ECHO-FGS.

Phthalate and DINCH metabolites in the urine of Hungarian schoolchildren: cumulative risk assessment and exposure determinants.

Parabens/Triclosan/Antimicrobials

Accumulation of Parabens, Their Metabolites, and Halogenated Byproducts in Migratory Birds of Prey: A Comparative Study in Texas and North Carolina, USA.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Utilizing machine learning to classify persistent organic pollutants in the serum of pregnant women: a predictive modeling approach.

PFAS

Monitoring of per- and polyfluoroalkyl substances (PFAS) in human blood samples collected in three regions with known PFAS releases in the environment and three control regions in South Germany.

Silicone Wristbands as a Personal Passive Sampler to Evaluate Indoor Exposure to Volatile and Non-volatile PFASs.

Per- and polyfluoroalkyl substances (PFAS) in homegrown crops: accumulation and human risk assessment.

Tissue Distribution of Emerging Per- and Polyfluoroalkyl Substances in Wild Fish Species from Qiantang River, east China: Comparison of 6:2 Cl-PFESA with PFOS.

Characterization of the Bioavailability of Per- and Polyfluoroalkyl Substances in Farmland Soils and the Factors Impacting Their Translocation to Edible Plant Tissues.

Identification of Emerging Per- and Polyfluoroalkyl Substances (PFAS) in E-waste Recycling Practices and New Precursors for Trifluoroacetic Acid.

Distribution and bioaccumulation of per- and polyfluoroalkyl substances (PFASs) in the Kuroshio Extension region of Northwest Pacific Ocean.

Current Challenges in Monitoring Low Contaminant Levels of Per- and Polyfluoroalkyl Substances in Water Matrices in the Field.

Have per- and polyfluoroalkyl substances (PFAS) infiltrated Florida’s freshwater springs?

Leaching of per- and polyfluoroalkyl substances (PFAS) from food contact materials with implications for waste disposal.

Pesticides

Biomonitoring of 2,4-dichlorophenoxyacetic acid (2,4-D) herbicide: A global view.

Metals/Metalloids

A Mixed Methods Approach to Understanding the Public Health Impact of a School-Based Citizen Science Program to Reduce Arsenic in Private Well Water [see related Invited Perspective: The All About Arsenic Program-A Blueprint for Leveraging Youth Engagement to Advance Water Justice.]

Arsenic speciation analysis in human urine for long term epidemiological studies: The Multi-Ethnic Study of Atherosclerosis (MESA).

Microplastics/Nanomaterials

Assessment of microplastics in human stool: A pilot study investigating the potential impact of diet-associated scenarios on oral microplastics exposure

Beyond the food on your plate: Investigating sources of microplastic contamination in home kitchens.

Microplastics are effective carriers of bisphenol A and facilitate its escape from wastewater treatment systems.

Granulated rubber in playgrounds and sports fields: A potential source of atmospheric plastic-related contaminants and plastic additives after runoff events.

Air Pollution

The effects of ambient air pollution exposure on Thoroughbred racehorse performance.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me and ask to join the EDC Science Weekly group EDC_research@googlegroups.com. The searchable archives are at https://groups.google.com/d/forum/edc_research or online at https://heeds.org/category/edc-science-weekly/. Feel free to forward this email. Compiled by Sarah Howard of Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

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