EDC Science Weekly, Dec. 16-23, 2022

Post author:HEEDS
Post published:December 23, 2022
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

I’ll be off next week so see you in January and happy holidays!

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

See the December issue of HEEDS Monthly for some upcoming events.

Regulations/Policy

Advancing exposure knowledge and its uptake into policy: The European exposure science strategy 2020-2030 (Special Issue). [see this special issue in Environ Int]

Unlocking India’s Potential in Managing Endocrine-Disrupting Chemicals (EDCs): Importance, Challenges, and Opportunities.

The HBM4EU chromates study – Outcomes and impacts on EU policies and occupational health practices. [also includes PFAS]

Risk assessment of food contact materials.

foodsafety4eu: paving the way for the food safety system of the future.

Toxicological Comparison of Pesticide Active Substances Approved for Conventional vs. Organic Agriculture in Europe.

Methods/Tools/Screening

Methods

From Protein Sequence to Structure: The Next Frontier in Cross Species Extrapolation for Chemical Safety Evaluations.

Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.

Computational chromatography: A machine learning strategy for demixing individual chemical components in complex mixtures.

New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs.

Assessment of the per- and polyfluoroalkyl substances analysis under the Stockholm Convention – 2018/2019.

The use of NAMs and omics data in risk assessment.

An interdisciplinary framework for derivation of occupational exposure limits. [from ExxonMobil]

Tools

PACEMweb: a tool for aggregate consumer exposure assessment.

Screening

Thyroid-on-a-chip: An Organoid Platform For In Vitro Assessment of Endocrine Disruption.

Predicting Endocrine Disruption Using Conformal Prediction – A Prioritization Strategy to Identify Hazardous Chemicals with Confidence.

Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework.

High-Throughput Screening of Toxicants that Modulate Extravillous Trophoblast Migration.

Physicochemical and bioinformatic characterization of Oreochromis niloticus vitellogenin as an endocrine disruption biomarker.

Advantages and Disadvantages of Two In Vitro Assays in Evaluating Aromatase Activity: “A Cell-Based and a Cell-Free Assay”.

Commentaries

Integrating a Chemicals Perspective into the Global Plastic Treaty.

The Importance of Fostering and Funding Scientific Research and Its Relevance to Environmental Toxicology and Chemistry.

Editorial: Application of computational tools to health and environmental sciences, Volume II. [intro to a research topic in Frontiers in Pharmacology]

Invited Perspective: Temporality and Recursive Dynamics in Stress-Pollution Interactions.

Aged before Their Time: Atrazine and Diminished Egg Quality in Mice. [Science Selection in EHP]

Nutritional Multitasking? Exploring Calcium Supplementation to Reduce Toxic Metal Effects. [Science Selection in EHP]

Reviews

Numerous Chemicals/Mixtures

South American National Contributions to Knowledge of the Effects of Endocrine Disrupting Chemicals in Wild Animals: Current and Future Directions.

A scientometric analysis of research trends on emerging contaminants in the field of cancer in 2012-2021.

Environmental endocrine disruptors and amphibian immunity: A bridge between the thyroid hormone axis and T cell development.

Microbiota analysis for risk assessment of xenobiotics: cumulative xenobiotic exposure and impact on human gut microbiota under One Health approach.

Toxicant exposure and the developing brain: A systematic review of the structural and functional MRI literature.

BPA/Phenols

Human exposure to bisphenol A (BPA) through medical-hospital devices: a systematic review.

Susceptibility of male reproductive system to bisphenol A, an endocrine disruptor: Updates from epidemiological and experimental evidence.

[Bisphenol A and breast cancer: State of knowledge and meta-analysis]. [in French]

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Association between polychlorinated biphenyl exposure and thyroid hormones: a systematic review and meta-analysis.

Polychlorinated biphenyls: A review of recent updates on food safety and environmental monitoring, health and toxicological implications, and analysis.

Perfluoroalkyl Substances

Per- and polyfluoroalkyl substances (PFAS) in breast milk and infant formula: A global issue.

Flame Retardants

Occurrence of organophosphorus esters in outdoor air fine particulate matter and comprehensive assessment of human exposure: A global systematic review.

A Review of Hydroxylated and Methoxylated Brominated Diphenyl Ethers in Marine Environments.

Pesticides

Organophosphate pesticides an emerging environmental contaminant: Pollution, toxicity, bioremediation progress, and remaining challenges.

Chemicals/materials of emerging concern in farmlands: sources, crop uptake and potential human health risks.

Multiple Neurological Effects Associated with Exposure to Organophosphorus Pesticides in Man.

Exposure Levels of Pyrethroids, Chlorpyrifos and Glyphosate in EU-An Overview of Human Biomonitoring Studies Published since 2000.

Metals/Metalloids

Gut as the target tissue of mercury and the extraintestinal effects.

Contemporary Comprehensive Review on Arsenic-Induced Male Reproductive Toxicity and Mechanisms of Phytonutrient Intervention.

Microplastics/Nanomaterials

Gross Negligence: Impacts of Microplastics and Plastic Leachates on Phytoplankton Community and Ecosystem Dynamics.

Air Pollution

Different components of air pollutants and neurological disorders.

Adverse Effects of Black Carbon (BC) Exposure during Pregnancy on Maternal and Fetal Health: A Contemporary Review.

Pharmaceuticals/Personal Care Products

Environmental impacts of the ultraviolet filter oxybenzone.

Environmental exposure to non-steroidal anti-inflammatory drugs and potential contribution to eggshell thinning in birds.

Miscellaneous

Potential Endocrine Disruption of Cyanobacterial Toxins, Microcystins and Cylindrospermopsin: A Review.

Human Health Studies

Numerous Chemicals/Mixtures

Plasma bisphenol a and phthalate levels in children with cerebral palsy: a case-control study.

Joint effects of per- and polyfluoroalkyl substance alternatives and heavy metals on renal health: A community-based population study in China.

BPA/Phenols

Associations between urinary concentrations of bisphenols and serum concentrations of sex hormones among US. Males.

Phthalates

Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring autism spectrum disorder symptoms in early life: A birth cohort study.

Associations of early life phthalate exposures with adolescent lipid levels and insulin resistance: The HOME Study.

Associations between Phthalate Exposure and Gestational Age at Delivery in a Diverse Pregnancy Cohort.

Parabens/Triclosan/Antimicrobials

Concentrations of urinary parabens and reproductive hormones in Iranian women: Exposure and risk assessment.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Do good carefully: The long-term effects of low-dose DDT exposure in early childhood on education, marriage and employment.

Perfluoroalkyl Substances

Changes in perfluoroalkyl substances (PFAS) concentrations in human milk over the course of lactation: A study in Ronneby mother-child cohort.

Cross-sectional associations of maternal PFAS exposure on SARS-CoV-2 IgG antibody levels during pregnancy.

Prenatal perfluoroalkyl substances exposure and neurodevelopment in toddlers: Findings from SMBCS.

Perfluoroalkyl Substance Serum Concentrations and Cholesterol Absorption-Inhibiting Medication Ezetimibe.

Pesticides

Alteration of oral microbiome composition in children living with pesticide-exposed farm workers.

The association between organophosphate pesticide exposure and methylation of paraoxonase-1 in children with attention-deficit/hyperactivity disorder.

Occupational and environmental pesticide exposure and associated health risks among pesticide applicators and non-applicator residents in rural Ethiopia.

Metals/Metalloids

Maternal Metals Exposure and Infant Weight Trajectory: The Japan Environment and Children’s Study (JECS).

Associations of metal exposure with hyperuricemia and gout in general adults.

Association of Community Water Lead Levels and Erythropoietin Stimulating Agent Use among End-Stage Kidney Disease Patients.

Association of Blood Heavy Metal Exposure with Atherosclerotic Cardiovascular Disease (ASCVD) Among White Adults: Evidence from NHANES 1999-2018.

Relationships Between Indicators of Metabolic Disorders and Selected Concentrations of Bioelements and Lead in Serum and Bone Tissue in Aging Men.

In utero arsenic exposure increases DNA damage and gene expression changes in umbilical cord mesenchymal stem cells (UC-MSCs) from newborns as well as in UC-MSC differentiated hepatocytes.

Adverse Health Effects and Mercury Exposure in a Colombian Artisanal and Small-Scale Gold Mining Community.

Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function among Chinese community-dwelling older adults.

Comparison of monoamine oxidase and selected heavy metal levels in the blood and the workplace among e-waste sorting workers in Ubon Ratchathani Province, Thailand.

Air Pollution

Long-term air pollution exposure and Parkinson’s disease mortality in a large pooled European cohort: An ELAPSE study.

Do wildfires exacerbate COVID-19 infections and deaths in vulnerable communities? Evidence from California.

The relationship between hair metabolites, air pollution exposure and gestational diabetes mellitus: A longitudinal study from pre-conception to third trimester.

Miscellaneous

Adolescence is a sensitive period for acrylamide-induced sex hormone disruption: Evidence from NHANES populations and experimental mice.

Associations between repeated measurements of urinary polycyclic aromatic hydrocarbon metabolites and thyroid hormones among reproductive-aged men.

Laboratory Studies

Numerous Chemicals/Mixtures

Acute Toxicity of Daphnia magna Neonates Exposed to Single and Composite Mixtures of Four Emerging Contaminants.

Toxicological effect and enzymatic disorder of non-studied emerging contaminants in Artemia salina model.

Accounting for transgenerational effects of toxicant exposure in population models alters the predicted long-term population status.

Lipophilicity profiling and cell viability assessment of a selected panel of endocrine disruptors.

Exposure to lead and dietary furan intake aggravates hypothalamus-pituitary-testicular axis toxicity in chronic experimental rats.

Prediction of the toxic effects of (agro) chemical mixtures on organisms using simple time-based models.

Di-(2-ethylhexyl) phthalate aggravates fine particulate matter-induced asthma in weanling mice due to T follicular helper cell-dependent response.

BPA/Phenols

The effects of bisphenols on the cardiovascular system ex vivo and in vivo.

Effects of Perinatal Exposure to Bisphenol A on Induction of Prostate Cancer in Sprague Dawley Rats by MNU and Testosterone.

Bisphenol S Impairs Behaviors through Disturbing Endoplasmic Reticulum Function and Reducing Lipid Levels in the Brain of Zebrafish.

Bisphenol S induces oxidative stress-mediated impairment of testosterone synthesis by inhibiting the Nrf2/HO-1 signaling pathway.

Neurotoxicity of Bisphenol A and the Impact of Melatonin Administration on Oxidative Stress, ERK/NF-kB Signaling Pathway, and Behavior in Rats.

In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals.

Bisphenol A exacerbates anxiety-like behavior and neuroinflammation in prefrontal cortex of adult obese mice.

Renoprotective effect of N-acetylcystein and vitamin E in bisphenol A-induced rat nephrotoxicity; Modulators of Nrf2/ NF-κB and ROS signaling pathway.

Melatonin attenuates bisphenol A-induced colon injury by dual targeting mitochondrial dynamics and Nrf2 antioxidant system via activation of SIRT1/PGC-1α signaling pathway.

Toxicity of bisphenol A and its replacements in the mice Leydig cells in vitro.

Phthalates

Impact of mono(2-ethylhexyl) phthalate (MEHP) on the development of mouse embryo in vitro.

MicroRNA-375 Mediated Regulation on Pre-mRNA Processing Factor 3 in Zebrafish Embryos Exposed to Di-(2-ethylhexyl)phthalate at Low Concentrations.

Parabens/Triclosan/Antimicrobials

Thyroid hormone disrupting potentials of benzisothiazolinone in embryo-larval zebrafish and rat pituitary GH3 cell line.

Triclosan Reprograms Immunometabolism and Activates the Inflammasome in Human Macrophages.

Acute toxicity, oxidative stress, and apoptosis due to short-term triclosan exposure and multi- and transgenerational effects on in vivo endpoints, antioxidant defense, and DNA damage response in the freshwater water flea Daphnia magna.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Polyhalogenated carbazoles induce hepatic metabolic disorders in mice via alteration in gut microbiota.

2,3,7,8-Tetrachlorodibenzo-dioxin induces liver lipid metabolism disorder via the ROS/AMPK/CD36 signaling pathway.

In vitro hepatic metabolism of polychlorinated biphenyls with different chlorine-substituted structures in rats and humans: Kinetics, metabolism, and potential nuclear receptor affinities.

Perfluoroalkyl Substances

Variability in fecal metabolome depending on age, PFBS pollutant, and fecal transplantation in zebrafish: A non-invasive diagnosis of health.

Perfluorotetradecanoic Acid (PFTeDA) Induces Mitochondrial Damage and Oxidative Stress in Zebrafish (Danio rerio) Embryos/Larvae.

¹ H-NMR Metabolomics Analysis of Arabidopsis thaliana Exposed to Perfluorooctanoic Acid and Perfluoroctanesulfonic Acid.

Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure.

Flame Retardants

Postnatal exposure to low-dose tetrabromobisphenol A increases the susceptibility of mammal testes to chemical-induced spermatogenic stress in adulthood.

Developmental toxicity of TCBPA on the nervous and cardiovascular systems of zebrafish (Danio rerio): A combination of transcriptomic and metabolomics.

Genotoxic and Toxic Effects of The Flame Retardant Tris(Chloropropyl) Phosphate (TCPP) in Human Lymphocytes, Microalgae and Bacteria.

Pesticides

Azole pesticide products and their hepatic metabolites cause endocrine disrupting potential by suppressing the homo-dimerization of human estrogen receptor alpha.

Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2/GSH/GPX4 axis exacerbates hepatotoxicity.

Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring.

Maternal Exposure to Glyphosate-based Herbicide Causes Changes in the Vascular Function of Offspring Adult Rats.

Metabolic profiling and in vitro–in vivo extrapolation of furathiocarb in mammalian hepatic microsomes.

Thiamethoxam affects the developmental stages of banded gourami (Trichogaster fasciata).

Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury in rats by modulating SIRT1 and Nrf2/HO-1 signaling.

Behavioral and neurochemical impairments after intranasal administration of chlorpyrifos formulation in mice.

Evaluation of Toxic Effects Induced by Sub-Acute Exposure to Low Doses of α-Cypermethrin in Adult Male Rats.

Lambda-cyhalothrin induces lipid accumulation in mouse liver is associated with AMPK inactivation.

Is nanoparaquat safer than bulk paraquat? An in vitro and in vivo evaluation.

In vivo exposure to pyriproxyfen causes ovarian oxidative stress and inhibits follicle maturation in zebrafish.

Gestational Exposure to Cyfluthrin through Endoplasmic Reticulum (ER) Stress-Mediated PERK Signaling Pathway Impairs Placental Development.

Ecotoxicological Risk Assessment of Actellic 50 EC Insecticide on Non-Target Organisms in Parallel with the Application of Standardized Tests.

Metals/Metalloids

Copper and Zinc Treatments Alter the Thyroid Endocrine System in Zebrafish Embryos/Larvae.

Arsenic-induced differential inflammatory responses in mouse thymus involves NF-κB/STAT-3 disruption, Treg bias and autophagy activation.

Microplastics/Nanomaterials

Maternal exposure to polystyrene microplastics alters placental metabolism in mice.

Toxicity assessment of polyethylene microplastics in combination with a mix of emerging pollutants on Physalaemus cuvieri tadpoles.

Polystyrene microplastics induce gut microbiome and metabolome changes in Javanese medaka fish (Oryzias javanicus Bleeker, 1854).

Influence of microplastics on the photodegradation of perfluorooctane sulfonamide (FOSA).

Application of transcriptome profiling to inquire into the mechanism of nanoplastics toxicity during Ciona robusta embryogenesis.

Evaluation of toxicity of polystyrene microplastics under realistic exposure levels in human vascular endothelial EA.hy926 cells.

Nanoplastics promote arsenic-induced ROS accumulation, mitochondrial damage and disturbances in neurotransmitter metabolism of zebrafish (Danio rerio).

Morphological Alterations in the Early Developmental Stages of Zebrafish (Danio rerio; Hamilton 1822) Induced by Exposure to Polystyrene Microparticles.

Pharmaceuticals/Personal Care Products

Low concentrations of benzophenone-type UV-filters impair testis development in the amphibian Xenopus laevis.

Thyroid endocrine disruption and neurotoxicity of gestodene in adult female mosquitofish (Gambusia affinis).

Effects of the Antidepressant Amitriptyline on Juvenile Brown Trout and Their Modulation by Microplastics.

Miscellaneous

Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a]pyrene exposure: Cellular and transcriptomic insights.

Comparative cytotoxicity, endocrine-disrupting effects, oxidative stress of halophenolic disinfection byproducts and the underlying molecular mechanisms revealed by transcriptome analysis.

Cytotoxicity assessment and suspected screening of plastic additives in bioplastics of single-use household items.

Hormone-mediated multi- and trans-generational reproductive toxicities of 1-ethyl-3-methylimidazolium hexafluorophosphate on Caenorhabditis elegans.

Evaluating the alterations of the estrogen-responsive genes in Cyprinodon variegatus larvae for biomonitoring the impacts of estrogenic endocrine disruptors (EEDs).

Exposure/Environment Studies

Numerous Chemicals/Mixtures

Emerging Contaminants and New POPs (PFAS and HBCDD) in Endangered Southern Resident and Bigg’s (Transient) Killer Whales (Orcinus orca): In Utero Maternal Transfer and Pollution Management Implications.

Co-variate adjusted associations between serum concentrations of selected perfluoroalkyl substances and urinary concentrations of selected arsenic species.

Postnatal exposure to organic pollutants in maternal milk in north-western Spain. [POPs, PBDEs, pesticides, PAHs]

Co-exposure levels of volatile organic compounds and metals/metalloids in children: Implications for E-waste recycling activity prediction.

Bottled water contaminant exposures and potential human effects.

Exposure to Polybrominated Diphenyl Ethers and Phthalates in China: A Disease Burden and Cost Analysis.

BPA/Phenols

An Assessment of Mass Flows, Removal and Environmental Emissions of Bisphenols in a Sequencing Batch Reactor Wastewater Treatment Plant.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Legacy Chemical Pollutants in House Dust of Homes of Pregnant African Americans in Atlanta.

First WHO/UNEP survey of the current concentrations of persistent organic pollutants in human milk in Morocco.

Detection of indicator polychlorinated biphenyls (I-PCBs) and polycyclic aromatic hydrocarbons (PAHs) in cow milk from selected areas of Dhaka, Bangladesh and potential human health risks assessment.

Preliminary assessment of persistent organic pollutants (POPs) in tissues of Risso’s dolphin (Grampus griseus) specimens stranded along the Italian coasts.

Perfluoroalkyl Substances

Perfluoroalkyl and polyfluoroalkyl substances in cord serum of newborns and their potential factors.

Isomer-Specific Serum Concentrations of Perfluorooctane Sulfonic Acid among U.S. Adults: Results from the National Health and Nutrition Examination Survey (NHANES) and the Study of Women’s Health Across the Nation Multi-Pollutant Study (SWAN-MPS).

Federal PFAS Testing and Tribal Public Water Systems. [see related Invited Perspective: Tribal Water Issues Exemplified by the Navajo Nation.]

Quantitative relationships of perfluoroalkyl acids in drinking water associated with serum concentrations above background in adults living near contamination hotspots in Sweden.

Targeted PFAS analyses and extractable organofluorine – Enhancing our understanding of the presence of unknown PFAS in Norwegian wildlife.

Spatiotemporal variations and bioaccumulation of per- and polyfluoroalkyl substances and oxidative conversion of precursors in shallow lake water.

Direct evidence of the important role of proteins in bioconcentration and biomagnification of PFASs in benthic organisms based on comparison with OPEs.

Flame Retardants

Seasonal and source characteristics of organophosphorus flame retardants in air and house dust in Taiwan residential microenvironments: Implications for young children’s exposure and risk assessment using a probabilistic approach.

Exposure and Risk Assessment of Korean Firefighters to PBDEs and PAHs via Fire Vehicle Dust and Personal Protective Equipment.

Temporal trends in concentrations of brominated flame retardants in UK foodstuffs suggest active impacts of global phase-out of PBDEs and HBCDD.

Pesticides

Changes in concentration of pesticide residues in fruits and vegetables during household processing.

Outcome of the first survey of atrazine in drinking water from Ijebu-North, South-West, Nigeria: Human health risk and neurotoxicological implications.

Detections of organophosphate and pyrethroid insecticide metabolites in urine and sweat obtained from women during infrared sauna and exercise: A pilot crossover study.

Detection of Neonicotinoid Insecticides and Their Metabolites in Human Cerebrospinal Fluid.

Impact of drinking water treatment processes on the residues of plant protection products for consumer and aquatic risk assessment: theoretical and experimental studies.

Relationship between Pesticide Standards for Classification of Water Bodies and Ecotoxicity: A Case Study of the Brazilian Directive.

Trends of Total Applied Pesticide Toxicity in German Agriculture.

Microplastics/Nanomaterials

Atmospheric microplastics and nanoplastics as vectors of primary air pollutants – A theoretical study on the polyethylene terephthalate (PET) case.

Towards a Better Understanding of the Contribution of Wastewater Treatment Plants to the Microplastic Pollution in Receiving Waterways.

First evidence of microplastic contamination in ready-to-use packaged food ice cubes.

Microplastics in Widely Used Polypropylene-Made Food Containers.

Air Pollution/PAHs

Study on dietary intake, risk assessment, and molecular toxicity mechanism of benzo[α]pyrene in college students in China Bashu area.

Association of polycyclic aromatic hydrocarbons in moss with blood biomarker among nearby residents in Portland, Oregon.

Pharmaceuticals/Personal Care Products

Occurrence, potential sources, and risk assessment of pharmaceuticals and personal care products in atmospheric particulate matter in Hanoi, Vietnam.

Occurrence, ecological risk assessment and source apportionment of pharmaceuticals, steroid hormones and xenoestrogens in the Ghanaian aquatic environments.

Miscellaneous

Characteristics and Statistical Analysis of Large and above Hazardous Chemical Accidents in China from 2000 to 2020.

Urinary excretion of estrogenic chemicals following consumption of capsule coffee and French press coffee: A crossover study.

Tracing toxic chemical releases embodied in U.S. interstate trade and their unequal distribution.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me at sar…@gmail.com and ask to join the EDC Science Weekly group EDC_re…@googlegroups.com. The searchable archives are at https://groups.google.com/d/forum/edc_research or online at https://heeds.org/category/edc-science-weekly/. Compiled by Sarah Howard, Diabetes and Environment and HEEDS, a program of Environmental Health Sciences.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.