EDC Science Weekly, Dec. 23, 2021 – Jan. 6, 2022

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed over the past few weeks.

Contents: Events, Methods/Tools/Screening, Commentaries/Conference Summaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Virtual conference Jan 10-13: PPTOX VII: International Conference on Prenatal Programming and Toxicity

Virtual meeting Jan 20-21: EURION Cluster Annual Meeting (the European Cluster to Improve Identification of Endocrine Disruptors)

Webinar Jan. 25: The role of epidemiology in risk assessment: A case study of five ortho-phthalates [EDC Strategies Partnership]

Methods/Tools/Screening

Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview.

Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals.

Computational methods on food contact chemicals: Big data and in silico screening on nuclear receptors family.

Biological effect and chemical monitoring of Watch List substances in European surface waters: Steroidal estrogens and diclofenac – Effect-based methods for monitoring frameworks.

Occupational Exposure Assessment Tools in Europe: A Comprehensive Inventory Overview.

The design of a matrix linking work situations to chemical health risk at the workplace.

Systems Thinking for Effective Interventions in Global Environmental Health.

Solution to bisphenol A measurement challenge.

A machine learning-driven approach for prioritizing food contact chemicals of carcinogenic concern based on complementary in silico methods.

HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol.

Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity.

Methods for the analysis of endocrine disrupting chemicals in selected environmental matrixes.

Commentaries/Conference Summaries

Considering Toxic Chemicals in the Etiology of Autism.

Invited Perspective: Phthalates and Blood Pressure: the Unknowns of Dietary Factors. [re Maternal Phthalates Exposure and Blood Pressure during and after Pregnancy in the PROGRESS Study. in EHP]

Contaminants of Emerging Concern (CECs): Occurrence and Fate in Aquatic Ecosystems.

Human and ecological health effects of nanoplastics: may not be a tiny problem.

The January 2022 issue of the American Journal of Public Health has a section on New Frontiers of Environmental Justice, including these editorials and articles:

Reviews

Numerous Chemicals/Mixtures

Environmental Factors as Diabetic Mediators-A Mechanistic Approach.

The Impact of Endocrine-Disrupting Chemicals in Male Fertility: Focus on the Action of Obesogens.

Obesogens in Children-An Uncharted Territory.

Epigenetic Transgenerational Inheritance of the Effects of Obesogen Exposure.

Metabolic Syndrome and Endocrine Disrupting Chemicals: An Overview of Exposure and Health Effects.

Xenoestrogens impact brain estrogen receptor signaling during the female lifespan: A precursor to neurological disease?

A systematic review of the mental health risks and resilience among pollution-exposed adolescents.

Raising the Alarm: Environmental Factors in the Onset and Maintenance of Chronic (Low-Grade) Inflammation in the Gastrointestinal Tract.

Environmental Factors Influencing COVID-19 Incidence and Severity.

Environmental Exposures and Congenital Heart Disease.

Emerging contaminants of high concern for the environment: Current trends and future research.

BPA/Phenols

Association between urinary bisphenol A concentrations and semen quality: a meta-analytic study.

Phthalates

Review of the Existing Evidence for Sex-Specific Relationships between Prenatal Phthalate Exposure and Children’s Neurodevelopment.

Oxidative stress induced by phthalates in mammals: State of the art and potential biomarkers

Exposure to Dibutyl Phthalate and Reproductive-Related Outcomes in Animal Models: Evidence From Rodents Study.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

A perspective on persistent toxicants in veterans and amyotrophic lateral sclerosis: identifying exposures determining higher ALS risk.

Perfluoroalkyl Substances

Per- and polyfluoroalkyl substances exposure science: current knowledge, information needs, future directions.

Flame Retardants

Review of the environmental occurrence/analytical techniques, degradation and toxicity of TBBPA and its derivatives.

Pesticides

Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides.

Pesticides and Male Fertility: A Dangerous Crosstalk.

Association between exposure to pesticides and allergic diseases in children and adolescents: a systematic review with meta-analysis.

Effects of glyphosate exposure on honeybees.

Systematic Review of Calcium Channels and Intracellular Calcium Signaling: Relevance to Pesticide Neurotoxicity.

Elements to increase translation in pyrethroid epidemiology research: A review.

Pre-Conceptional and Prenatal Exposure to Pesticides and Pediatric Neuroblastoma. A Meta-Analysis of Nine Studies.

Potentially Toxic Elements

Heavy Metal Accumulation in Rice and Aquatic Plants Used as Human Food: A General Review.

Genotoxicity of Mercury and Its Derivatives Demonstrated In Vitro and In Vivo in Human Populations Studies. Systematic Review.

Metabolic reprogramming in the arsenic carcinogenesis.

Microplastics/Nanomaterials

Metal/metal oxide nanoparticles: Toxicity concerns associated with their physical state and remediation for biomedical applications.

Advances in endocrine toxicity of nanomaterials and mechanism in hormone secretion disorders.

Environmental Impacts of Microplastics and Nanoplastics: A Current Overview.

Separation and characterization of microplastic and nanoplastic particles in marine environment.

A review of microplastic pollution in commercial fish for human consumption.

The COVID-19 pandemic reshapes the plastic pollution research – A comparative analysis of plastic pollution research before and during the pandemic.

The impacts of plastics on aquatic insects.

Microplastics in the Food Chain.

Pharmaceuticals/Personal Care Products

Analysis of Fragrance Allergens in Personal Care Products, Toys, and Water Samples: A Review.

Miscellaneous

Safety Risks of Plant Fiber/Plastic Composites (PPCs) Intended for Food Contact: A Review of Potential Hazards and Risk Management Measures.

Ethylene oxide derived glycol ethers: A review of the alkyl glycol ethers potential to cause endocrine disruption.

BXD Recombinant Inbred Mice as a Model to Study Neurotoxicity.

Relationship Between Polycyclic Aromatic Hydrocarbons and Cardiovascular Diseases: A Systematic Review.

Human Health Studies

Numerous Chemicals/Mixtures

Dietary Habits and Relationship with the Presence of Main and Trace Elements, Bisphenol A, Tetrabromobisphenol A, and the Lipid, Microbiological and Immunological Profiles of Breast Milk.

Effects of genetic polymorphisms in body mass index according to dietary exposure to bisphenols and parabens.

Prenatal Exposure to Chemical Mixtures and Cognitive Flexibility among Adolescents.

Urinary concentrations of phenols and parabens and incident diabetes in midlife women: The Study of Women’s Health Across the Nation.

High Thyroid Cancer Incidence Rate in a Community near a Landfill: A Descriptive Epidemiological Assessment.

BPA/Phenols

Single and mixed effects of prenatal exposure to multiple bisphenols on hemoglobin levels and the risk of anemia in pregnant women.

The Association between Bisphenol A, Steroid Hormones, and Selected MicroRNAs Levels in Seminal Plasma of Men with Infertility.

Phthalates

Urinary phthalate metabolites and arterial stiffness: A panel study.

Parabens/Triclosan/Antimicrobials

Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study.

Urinary parabens and their derivatives associated with oxidative stress biomarkers in children from South and Central China: Repeated measures.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Alterations in Regional Brain Regional Volume Associated with Dioxin Exposure in Men Living in the Most Dioxin-Contaminated Area in Vietnam: Magnetic Resonance Imaging (MRI) Analysis Using Voxel-Based Morphometry (VBM).

Follicular fluid and blood levels of persistent organic pollutants and reproductive outcomes among women undergoing assisted reproductive technologies.

Perfluoroalkyl Substances

Prenatal exposure to per- and polyfluoroalkyl substances, fetal thyroid hormones, and infant neurodevelopment.

PFAS Concentrations and Cardiometabolic Traits in Highly Exposed Children and Adolescents.

Flame Retardants

Association of urinary organophosphate esters level with sex steroid hormones levels in adult males: A nationwide study, NHANES 2013-2014.

Pesticides

Household pesticide exposures and infant gross motor development in the MADRES cohort.

Pesticide residue intake from fruits and vegetables and alterations in the serum metabolome of women undergoing infertility treatment.

Urinary Organophosphate Metabolites and Metabolic Biomarkers of Conventional and Organic Farmers in Thailand.

Environmental risk factors for reduced kidney function due to undetermined cause in India: an environmental epidemiologic analysis.

Organophosphate pesticide exposure as a risk factor for attempted suicide in Cape Town, South Africa: A case-control study.

The Parental Pesticide and Offspring’s Epigenome Study: Towards an Integrated Use of Human Biomonitoring of Exposure and Effect Biomarkers.

Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica.

Potentially Toxic Elements

Association between prenatal exposure to metal mixtures and early childhood allergic disease.

Maternal exposure to arsenic in drinking water and risk of congenital heart disease in the offspring.

Assessment of disease burden in the arsenic exposed population of Chapar village of Samastipur district, Bihar, India, and related mitigation initiative.

Health Risk Assessment of Exposure to 15 Essential and Toxic Elements in Spanish Women of Reproductive Age: A Case Study.

Risk of neurodegeneration among residents of electronic waste recycling areas.

Association of Blood Mercury Levels with the Risks of Overweight and High Waist-to-Height Ratio in Children and Adolescents: Data from the Korean National Health and Nutrition Examination Survey.

Association of heavy metals and trace elements in renal cell carcinoma: A case-controlled study.

Microplastics

Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status.

Air Pollution

From a special issue on Climate Change and Reproductive, Perinatal and Paediatric Health in Paediatr Perinat Epidemiol,

Air pollution and fecundability: Results from a Danish preconception cohort study [related commentary: Is ambient air pollution a risk factor for fecundity? ]
The association between wildfire exposure in pregnancy and foetal gastroschisis: A population-based cohort study [related commentary: Wildfires in Pregnancy: Potential Threats to the Newborn.]
Impacts of climate change on reproductive, perinatal and paediatric health [intro editorial]

Six Air Pollutants Associated With Increased Risk of Thyroid Nodules: A Study of 4.9 Million Chinese Adults.

Laboratory Studies

Numerous Chemicals/Mixtures

Protracted Impairment of Maternal Metabolic Health in Mouse Dams Following Pregnancy Exposure to a Mixture of Low Dose Endocrine-Disrupting Chemicals, a Pilot Study.

Combined Toxicity of Xenobiotics Bisphenol A and Heavy Metals on Zebrafish Embryos (Danio rerio).

Mixture toxicity prediction of substances from different origin sources in Daphnia magna.

Targeted and untargeted metabolomic analysis of Procambarus clarkii exposed to a “chemical cocktail” of heavy metals and diclofenac.

BPA/Phenols

Pubertal Bisphenol A exposure increases adult rat serum testosterone by resetting pituitary homeostasis.

Physiological, biochemical, and hormonal changes in rats exposed to bottled water left in a hot car and the freezer.

Sex-specific effects of bisphenol S with tissue-specific responsiveness in adult zebrafish: The antiandrogenic and antiestrogenic effects.

Bisphenol S exposure accelerates the progression of atherosclerosis in zebrafish embryo-larvae.

Bisphenol S exposure induces intestinal inflammation: An integrated metabolomic and transcriptomic study.

Bisphenol-A analogs induce lower urinary tract dysfunction in male mice.

Bisphenol A induces apoptosis and autophagy in murine osteocytes MLO-Y4: Involvement of ROS-mediated mTOR/ULK1 pathway.

Maternal Exposure to Bisphenol A Impacts on Fecundity in F1 and F2 Generations in Drosophila melanogaster.

TET1 mediated male reproductive toxicity induced by BPA at low dose through Catsper-Ca²⁺ signaling pathway.

Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4α pathway in endothelial cells to promote the angiogenesis of colorectal cancer.

Phthalates

In vitro Impact of Genistein And Mono(2-ethylhexyl) Phthalate (MEHP) on the Eicosanoid Pathway in Spermatogonial Stem Cells.

Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary.

Parabens/Triclosan/Antimicrobials

New insights into inhibitory nature of triclosan on acetylcholinesterase activity.

Environmental relevant concentrations of triclosan affected developmental toxicity, oxidative stress, and apoptosis in zebrafish embryos.

Butylparaben Induces the Neuronal Death Through the ER Stress-Mediated Apoptosis of Primary Cortical Neurons.

Residual behaviors and metabolic pathway of ethylparaben in Drosophila melanogaster.

2,4-dichlorophenol exposure induces lipid accumulation and reactive oxygen species formation in zebrafish embryos.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage.

Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium.

Lack of Offspring Nrf2 Does Not Exacerbate the Detrimental Metabolic Outcomes Caused by In Utero PCB126 Exposure.

Effects of Different Intensity Exercise on Glucose Metabolism and Hepatic IRS/PI3K/AKT Pathway in SD Rats Exposed with TCDD.

Perfluoroalkyl Substances

Exposure to perfluorooctane sulfonate reduced cell viability and insulin release capacity of β cells.

Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua).

Per- and Polyfluoroalkyl Substances Target and Alter Human Prostate Stem-Progenitor Cells.

iTRAQ-Based Quantitative Proteomics Analysis of Sprague-Dawley Rats Liver Reveals Perfluorooctanoic acid-induced Lipid Metabolism and Urea Cycle Dysfunction.

Flame Retardants

Cytotoxic and Transcriptomic Effects in Avian Hepatocytes Exposed to a Complex Mixture from Air Samples, and Their Relation to the Organic Flame Retardant Signature.

Ecotoxicity assessment of triphenyl phosphate (TPhP) exposure in Hoplobatrachus rugulosus tadpoles.

Pesticides

Toxicity and Transgenerational Effects of Insecticides on Trichopria anastrephae (Hymenoptera: Diapriidae).

Multi- and trans-generational effects of chlorpyrifos exposures to Daphnia magna.

Autonomic behavioral impairment induced by simazine exposure during early life of male mouse is mediated by Lmx1a/Wnt1 pathway.

Chronic Dietary Exposure of Roosters to a Glyphosate-Based Herbicide Increases Seminal Plasma Glyphosate and AMPA Concentrations, Alters Sperm Parameters, and Induces Metabolic Disorders in the Progeny.

Inflammatory, Oxidative Stress, and Apoptosis Effects in Zebrafish Larvae after Rapid Exposure to a Commercial Glyphosate Formulation.

Altered uterine angiogenesis in rats treated with a glyphosate-based herbicide.

Detection of imidacloprid and metabolites in Northern Leopard frog (Rana pipiens) brains.

Combined Developmental Toxicity of the Pesticides Difenoconazole and Dimethomorph on Embryonic Zebrafish.

The sexual reproduction of the nontarget planarian Girardia tigrina is affected by ecologically relevant concentrations of difenoconazole: new sensitive tools in ecotoxicology.

Combined lethal toxicity, biochemical responses, and gene expression variations induced by tebuconazole, bifenthrin and their mixture in zebrafish (Danio rerio).

Cyantraniliprole impairs reproductive parameters by inducing oxidative stress in adult female wistar rats.

Induced Hepatic Glutathione and Metabolomic Alterations Following Mixed Pesticide and Fertilizer Exposures in Juvenile Leopard Frogs (Lithobates sphenocephala).

Resveratrol alleviates cardiac apoptosis following exposure to fenitrothion by modulating the sirtuin1/c-Jun N-terminal kinases/p53 pathway through pro-oxidant and inflammatory response improvements: In vivo and in silico studies.

Toxicological Effect and Molecular Mechanism of the Chiral Neonicotinoid Dinotefuran in Honeybees.

Non-additive gene interactions underpin molecular and phenotypic responses in honey bee larvae exposed to imidacloprid and thymol.

Effects of Pesticides on Longevity and Bioenergetics in Invertebrates-The Impact of Polyphenolic Metabolites.

Juvenile African Clawed Frogs (Xenopus laevis) Express Growth, Metamorphosis, Mortality, Gene Expression, and Metabolic Changes When Exposed to Thiamethoxam and Clothianidin.

Effects of Sub-Chronic Exposure to Imidacloprid on Reproductive Organs of Adult Male Rats: Antioxidant State, DNA Damage, and Levels of Essential Elements.

Cholinesterase activity as a potential biomarker for neurotoxicity induced by pesticides in vivo exposed Oreochromis niloticus (Nile tilapia).

Chlorocholine chloride induced testosterone secretion inhibition mediated by endoplasmic reticulum stress in primary Leydig cells.

Simazine perturbs the maturational competency of mouse oocyte through inducing oxidative stress and DNA damage.

Potentially Toxic Elements

Untargeted Metabolomics Reveals a Complex Impact on Different Metabolic Pathways in Scallop Mimachlamys varia (Linnaeus, 1758) after Short-Term Exposure to Copper at Environmental Dose.

Life History Traits in Two Drosophila Species Differently Affected by Microbiota Diversity under Lead Exposure.

LC/MS/MS-Based Liver Metabolomics to Identify Chronic Liver Injury Biomarkers Following Exposure to Arsenic in Rats.

Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver.

Neurobehavioral and neurochemical effects of perinatal arsenite exposure in Sprague-Dawley rats.

The mechanism underlying arsenic-induced PD-L1 upregulation in BEAS-2B cells.

Leptin and adiponectin synthesis and secretion in mature 3T3-L1 adipocytes are differentially down-regulated by arsenic and palmitic acid exposure throughout different stages of adipogenesis.

Cadmium-induced neurotoxic effects on rat basal forebrain cholinergic system through thyroid hormones disruption.

Microplastics/Nanomaterials

Microplastics boost the accumulation of tetrabromobisphenol A in a commercial clam and elevate corresponding food safety risks.

Shape, size, and polymer dependent effects of microplastics on Daphnia magna.

Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.).

From bottle to microplastics: Can we estimate how our plastic products are breaking down?

Uptake and toxicity of polystyrene micro/nanoplastics in gastric cells: Effects of particle size and surface functionalization.

Combined effects of polystyrene microplastics and cadmium on oxidative stress, apoptosis, and GH/IGF axis in zebrafish early life stages.

First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species.

Behaviors and biochemical responses of macroinvertebrate Corbicula fluminea to polystyrene microplastics.

Behavior and mechanism of atrazine adsorption on pristine and aged microplastics in the aquatic environment: Kinetic and thermodynamic studies.

Impact of polystyrene microplastics on major marine primary (phytoplankton) and secondary producers (copepod).

Comparison of Different Commercial Nanopolystyrenes: Behavior in Exposure Media, Effects on Immune Function and Early Larval Development in the Model Bivalve Mytilus galloprovincialis.

Synthesis, Characterisation, Photocatalytic Activity, and Aquatic Toxicity Evaluation of TiO₂ Nanoparticles.

Kinetics of Silver Accumulation in Tissues of Laboratory Mice after Long-Term Oral Administration of Silver Nanoparticles.

Pharmaceuticals/Personal Care Products

Hazard assessment of beta-lactams: Integrating in silico and QSTR approaches with in vivo zebrafish embryo toxicity testing.

Proteomics of sea bass skin-scales exposed to the emerging pollutant fluoxetine compared to estradiol.

Miscellaneous

Comparative Toxicity Analyses from Different Endpoints: Are New Cyclic Disinfection Byproducts (DBPs) More Toxic than Common Aliphatic DBPs?

In vitro-in vivo biotransformation and phase I metabolite profiling of benzo[a]pyrene in Gulf killifish (Fundulus grandis) populations with different exposure histories.

Exposure/Environment Studies

Numerous Chemicals/Mixtures

Determination of contamination levels for multiple endocrine disruptors in hair from a non-occupationally exposed population living in Liege (Belgium).

Watershed-Scale Risk to Aquatic Organisms from Complex Chemical Mixtures in the Shenandoah River.

Multi-analyte gas chromatography-mass spectrometry method to monitor bisphenols, musk fragrances, ultraviolet filters, and pesticide residues in seafood.

Blubber Cortisol-Based Approach to Explore the Endocrine Responses of Indo-Pacific Humpback Dolphins (Sousa chinensis) to Diet Shifts and Contaminant Exposure.

Long-lasting effects of chronic exposure to chemical pollution on the hologenome of the Manila clam.

Occurrence of bisphenols and benzophenone UV filters in wild brown mussels (Perna perna) from Algoa Bay in South Africa.

BPA/Phenols/Phthalates

Occurrence, spatial distribution, and main source identification of ten bisphenol analogues in the dry season of the Pearl River, South China.

Analysis of alkylphenols, bisphenols and alkylphenol ethoxylates in microbial-fermented functional beverages and bottled water: Optimization of a dispersive liquid-liquid microextraction protocol based on natural hydrophobic deep eutectic solvents.

Impacts of brewing time, brewing temperature and brands on the leaching of phthalates and bisphenol A in dry tea.

Parabens/Triclosan/Antimicrobials

Occurrence and human exposure assessment of parabens in water sources in Osun State, Nigeria.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Bioaccumulation of organochlorine pesticides in Antarctic krill (Euphausia superba): Profile, influencing factors, and mechanisms.

Perfluoroalkyl Substances

Longitudinal poly- and perfluoroalkyl substances (PFAS) levels in Dutch infants.

Quantitation of linear and branched perfluoroalkane sulfonic acids (PFSAs) in women and infants during pregnancy and lactation.

Chemical-specific determinants for pre-conceptional exposure to emerging and legacy per- and polyfluoroalkyl substances.

Disposition of Fluorine on New Firefighter Turnout Gear.

Tissue concentrations of per- and polyfluoroalkyl substances (PFAS) in German freshwater fish: Derivation xof fillet-to-whole fish conversion factors and assessment of potential risks.

Analysis of per- and polyfluoroalkyl substances in Houston Ship Channel and Galveston Bay following a large-scale industrial fire using ion-mobility-spectrometry-mass spectrometry.

Practical implications of perfluoroalkyl substances adsorption on bottle materials: Isotherms.

Per- and Polyfluoroalkyl Substances in Contaminated Soil and Groundwater at Airports: A Canadian Case Study.

Perfluoroalkyl acids (PFAAs) in the aquatic food web of a temperate urban lake in East China: Bioaccumulation, biomagnification, and probabilistic human health risk.

Per- and Polyfluorinated Alkyl Substances (PFAS) cycling within Michigan: Contaminated sites, landfills and wastewater treatment plants.

A baseline study of per- and polyfluoroalkyl substances (PFASs) in waterfowl from a remote Australian environment.

Biomanipulation impacts on per-and polyfluoroalkyl substances accumulation and trophic transfer in an eutrophic lake.

Flame Retardants

Influences of humic acid on the release of polybrominated diphenyl ethers from plastic waste in landfills under different environmental conditions.

Occurrence and temperature dependence of atmospheric gas-phase organophosphate esters in high-mountain areas (Pyrenees).

Determination of multiple organic flame retardants in maricultural water using High-volume/High-throughput Solid-phase extraction followed by liquid/gas chromatography tandem mass spectrometry.

Presence of organophosphate flame retardants (OPEs) in different functional areas in residential homes in Beijing, China.

Distribution of organophosphate esters influenced by human activities and fluvial-tidal interactions in the Dong Nai River System, Vietnam.

Gas-particle partition and size-segregated distribution of flame retardants in indoor and outdoor air: Reevaluation on the role of fine particles in human exposure.

Pesticides

Human Rights Perspective on Pesticide Exposure and Poisoning in Children: A Case Study of India.

Τemporal Variation in Pesticide Residues in Citrus Fruits from Chios, Greece, before and after the Development of an Integrated Pest Management Strategy (IPMS): A Five-Year Study (LIFE13 ENV GR/000414).

Human Exposure of Fipronil Insecticide and the Associated Health Risk.

The ubiquity of neonicotinoid contamination: Residues in seabirds with different trophic habits.

Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring.

Low-Level Groundwater Atrazine in High Atrazine Usage Nebraska Counties: Likely Effects of Excessive Groundwater Abstraction.

Glyphosate and glufosinate-ammonium in aquaculture ponds and aquatic products: Occurrence and health risk assessment.

Potentially Toxic Elements

Concentrations and determinants of lead, mercury, cadmium, and arsenic in pooled donor breast milk in Spain.

Long-term monitoring of mercury in young German adults: Time trend analyses from the German Environmental Specimen Bank, 1995-2018.

International Analysis of Sources and Human Health Risk Associated with Trace Metal Contaminants in Residential Indoor Dust.

Effects of Long-Term Lead Exposure on Antioxidant Enzyme Defense System in Organs of Brown Hare (Lepus europaeus Pallas) as a Bioindicator of Environmental Pollution in Croatia.

Mercury toxicity risk and corticosterone levels across the breeding range of the Yellow-breasted Chat.

Effects of Removal Conditions on Mercury Amount Remaining in the Oral Cavity and inside Drainage System after Removing Dental Amalgams.

Increase of mercury and methylmercury levels with depth in a fish assemblage.

Rethinking of Environmental Health Risks: A Systematic Approach of Physical-Social Health Vulnerability Assessment on Heavy-Metal Exposure through Soil and Vegetables.

Efficacy of Hair Total Mercury Content as a Biomarker of Methylmercury Exposure to Communities in the Area of Artisanal and Small-Scale Gold Mining in Madre de Dios, Peru.

A Food-Safety Risk Assessment of Mercury, Lead and Cadmium in Fish Recreationally Caught from Three Lakes in Poland.

Surface Flooding as a Key Driver of Groundwater Arsenic Contamination in Southeast Asia.

Global issues in setting legal limits on soil metal contamination: A case study of Chile.

Microplastics

Evidence of free tropospheric and long-range transport of microplastic at Pic du Midi Observatory.

Occurrence and characteristics of microplastics in fish of the Han River, South Korea: Factors affecting microplastic abundance in fish.

Atmospheric transport of microplastics during a dust storm.

Microplastics in two German wastewater treatment plants: Year-long effluent analysis with FTIR and Py-GC/MS.

The contamination of microplastics in China’s aquatic environment: Occurrence, detection and implications for ecological risk

Microplastics in the sediments of small-scale Japanese rivers: Abundance and distribution, characterization, sources-to-sink, and ecological risks.

Pharmaceuticals/Personal Care Products

Differences in personal care product use by race/ethnicity among women in California: implications for chemical exposures.

Fish consumption is an indicator of exposure to benzophenone derivatives: A probabilistic risk assessment in Taiwanese population.

Environmental and human health risk assessment of mixture of Covid-19 treating pharmaceutical drugs in environmental waters.

Pharmaceutical compounds used in the COVID-19 pandemic: A review of their presence in water and treatment techniques for their elimination.

Miscellaneous

Food, Beverage, and Feedstock Processing Facility Wastewater: a Unique and Underappreciated Source of Contaminants to U.S. Streams.

Migration of formaldehyde from ‘biobased’ bamboo/melamine cups: A Dutch retail survey.

A pilot study characterizing tetrachloroethylene exposure with exhaled breath in an impacted community.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different from dates added to PubMed. To see the searchable archives, please email me at sar…@gmail.com and ask to join the EDC Science Weekly group EDC_re…@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research or online at https://heeds.org/category/edc-science-weekly/. Feel free to forward this email. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

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