EDC Science Weekly, Feb 10 – 23, 2021

Post author:HEEDS
Post published:February 23, 2021
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Events, Regulations/Policy, Methods/Tools/Screening, Commentaries, Reviews, Human Health Studies, Laboratory Studies, Exposure/Environment Studies

Events

Book Release

Count Down, by Shanna Swan, PhD

Listen to the webinar today, Feb. 23, with Dr. Swan and a panel discussion about the book:

Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race

And read about the book in Environmental Health News, Count Down: The Infertility Crisis

Additional webinars

Feb. 24: Promoting Equity and Health: An Anticolonial Model from an Indigenous-Led Marine-Science Laboratory

Feb. 25: Prenatal Exposures to Phthalates, Oil and Gas, and Pesticides: Effects on Birth Outcomes and Developmental Disabilities

Mar. 3: Endocrine Disrupting Chemicals: Effects on Mothers, and Interactions with Lifestyle

Regulations/Policy

Regulating PFAS as a Chemical Class under the California Safer Consumer Products Program.

Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children.

A tiered approach to prioritizing registered pesticides for potential cancer hazard evaluations: implications for decision making.

Legislative Update: Regulating Ingredients in Personal Care Products.

Regulatory landscape of nanotechnology and nanoplastics from a global perspective.

New Report by the National Academies: The Use of Systematic Review in EPA’s Toxic Substances Control Act Risk Evaluations

Methods/Tools/Screening

Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications. [BPA]

Development of a quantitative chemical risk assessment (QCRA) procedure for contaminants of emerging concern in drinking water supply. [BPA]

Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening.

Commentaries

Fossil fuel air pollution blamed for 1 in 5 deaths worldwide. re article Global mortality from outdoor fine particle pollution generated by fossil fuel combustion: Results from GEOS-Chem

Moving from Protection to Prosperity: Evolving the U.S. Environmental Protection Agency for the next 50 years

Air pollution triggers inflammation and cardiovascular events: now is the time to act.

Microplastics and human health.

Science, consensus, and endocrine-disrupting chemicals: Rethinking disagreement in expert deliberations

We need a global science-policy body on chemicals and waste.

Moving Beyond the Term “Contaminants of Emerging Concern”.

Persistent Organic Pollutants (POPs) and Related Chemicals in the Global Environment: Some Personal Reflections.

Introduction to Special Issue: Computational Toxicology. [intro to a special issue of Chemical Research in Toxicology]

Reviews

Numerous EDCs

Endocrine Disruptors Acting on Estrogen and Androgen Pathways Cause Reproductive Disorders through Multiple Mechanisms: A Review.

Review of endocrine disruptors on male and female reproductive systems.

Emerging contaminants and biological effects in Arctic wildlife.

Mixtures

Use of Exposomic Methods Incorporating Sensors in Environmental Epidemiology.

Unravelling the chemical exposome in cohort studies: routes explored and steps to become comprehensive.

BPA/Phenols

The Putative Adverse Effects of Bisphenol A on Autoimmune Diseases.

Phthalates

Phthalate pollution: environmental fate and cumulative human exposure index using the multivariate analysis approach.

Exposure to phthalates: germline dysfunction and aneuploidy.

Prenatal exposure to phthalate esters and its impact on child development.

Perfluoroalkyl Substances

Evaluation of published bioconcentration factor (BCF) and bioaccumulation factor (BAF) data for per- and polyfluoroalkyl substances across aquatic species.

Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review.

Pesticides

Health problems in agricultural workers occupationally exposed to pesticides.

A comprehensive review of strobilurin fungicide toxicity in aquatic species: Emphasis on mode of action from the zebrafish model.

Potentially Toxic Elements

Mitochondrial Dysfunction in Arsenic-Induced Hepatotoxicity: Pathogenic and Therapeutic Implications.

Lead Poisoning in South African Children: The Hazard is at Home.

Chromium contamination and effect on environmental health and its remediation: A sustainable approaches.

Microplastics

Source, distribution and emerging threat of micro- and nanoplastics to marine organism and human health: Socio-economic impact and management strategies.

Is cell culture a suitable tool for the evaluation of micro- and nanoplastics ecotoxicity?

An ecotoxicological approach to microplastics on terrestrial and aquatic organisms: A systematic review in assessment, monitoring and biological impact.

From plastics to microplastics and organisms.

Evaluation of the available strategies to control the emission of microplastics into the aquatic environment.

Relevance and reliability of evidence for microplastic contamination in seafood: A critical review using Australian consumption patterns as a case study.

A review of human and animals exposure to polycyclic aromatic hydrocarbons: Health risk and adverse effects, photo-induced toxicity and regulating effect of microplastics.

Air Pollution

The impact of outdoor air pollution on COVID-19: a review of evidence from in vitro, animal, and human studies.

Early-Life Exposure to Environmental Air Pollution and Autism Spectrum Disorder: A Review of Available Evidence.

Ambient air pollution exposure and risk of chronic kidney disease: A systematic review of the literature and meta-analysis.

An updated systematic review on the association between atmospheric particulate matter pollution and prevalence of SARS-CoV-2.

Miscellaneous

Participatory Research for Environmental Justice: A Critical Interpretive Synthesis.

Macroinvertebrates as biomonitors of pollutants on natural sandy beaches: Overview and meta-analysis.

An update in toxicology of ageing.

Interventions to Improve Children’s Health by Improving the Housing Environment.

COVID-19: a review on SARS-CoV-2 origin, epidemiology, virology, clinical manifestations and complications with special emphasis on adverse outcome in Bhopal Gas Tragedy survivor.

Combining Effect Estimates Across Cohorts and Sufficient Adjustment Sets for Collaborative Research: A Simulation Study.

Human Health Studies

Numerous Chemicals

Association of 13 Occupational Carcinogens in Patients With Cancer, Individually and Collectively, 1990-2017.

BPA/Phenols

Effects of a dietary modification intervention on menstrual pain and urinary BPA levels: a single group clinical trial.

Effects of Bisphenol A Released From Composite Fillings on Reproductive Hormone Levels in Men.

Phthalates

Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study.

Urinary di(2-ethylhexyl)phthalate metabolite ratios in obese children of South Korea.

Association between Urinary Phthalate Metabolites and Markers of Endothelial Dysfunction in Adolescents and Young Adults.

Gestational Exposure to Phthalates and Social Responsiveness Scores in Children Using Quantile Regression: The EARLI and HOME Studies.

Parabens

Exposure to parabens and associations with oxidative stress in adults from South China.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Cases experienced different longitudinal changes in POPs compared to controls Pre- and post-diagnostic blood profiles of chlorinated persistent organic pollutants and metabolic markers in type 2 diabetes mellitus cases and controls; A pilot study.

Neoplastic and inflammatory skin disorders and serum levels of polychlorinated biphenyls in a population living in a highly polluted area.

Prenatal exposure to mixtures of persistent endocrine disrupting chemicals and early menarche in a population-based cohort of British girls.

Perfluoroalkyl Substances

Associations of exposure to perfluoroalkyl substances individually and in mixtures with persistent infections: Recent findings from NHANES 1999-2016.

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.

Associations of Perfluoroalkyl Substances with Prevalence of Metabolic Syndrome in Highly Exposed Young Adult Community Residents-A Cross-Sectional Study in Veneto Region, Italy.

Flame Retardants

Association between prenatal exposure to polybrominated diphenyl ethers and anogenital distance in girls at ages 0-4 years.

Pesticides

The associations among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of paraoxonases in children with attention deficit/hyperactivity disorder.

Serum concentrations of neonicotinoids, and their associations with lipid molecules of the general residents in Wuxi City, Eastern China.

Acetylcholinesterase activity and thyroid hormone levels in Ecuadorian adolescents living in agricultural settings where organophosphate pesticides are used.

Disruption of the Diurnal Cortisol Hormone Pattern by Pesticide Use in a Longitudinal Study of Farmers in Thailand.

Measuring butyrylcholinesterase activity and hematological parameters in farmers exposed to pesticides: a case and control study from Morocco.

Potentially Toxic Elements

Associations of essential and toxic metals/metalloids in whole blood with both disease severity and mortality in patients with COVID-19.

Developmental lead exposure and adult criminal behavior: A 30-year prospective birth cohort study.

Total mercury concentration in placental tissue, a good biomarker of prenatal mercury exposure, is associated with risk for neural tube defects in offspring.

Associations of Semen Quality with Seminal Non-essential Heavy Metals in Males from the Canary Islands.

Urine cadmium and acute myocardial infarction among never smokers in the Danish Diet, Cancer and Health cohort.

Arsenic, Blood Pressure, and Hypertension in the Strong Heart Family Study.

Physical activity, body mass index and arsenic metabolism among Mexican women.

Environmental metal exposures and kidney function of Guatemalan sugarcane workers.

Cadmium Intake as a Prognostic Factor in Endometrial Cancer: A Swedish Cohort-Based Study.

Metal biomarker mixtures and blood pressure in the United States: cross-sectional findings from the 1999-2006 National Health and Nutrition Examination Survey (NHANES).

Prenatal heavy metal exposures and atopic dermatitis with gender difference in 6-month-old infants using multipollutant analysis.

Air Pollution

Acute effects of short-term exposure to ambient air pollution on reproductive hormones in young males of the MARHCS study in China.

Association of Particulate Matter with Autoimmune Rheumatic Diseases among Adults in South Korea.

The Combined Effects of Fine Particulate Matter and Temperature on Preterm Birth in Seoul, 2010-2016.

Toxicological effects of personal exposure to fine particles in adult residents of Hong Kong.

Association of air pollution and meteorological variables with COVID-19 incidence: Evidence from five megacities in India.

Ambient particulate matter (PM₁, PM_2.5, PM₁₀) and childhood pneumonia: The smaller particle, the greater short-term impact?

Gene-environment interactions between air pollution and biotransformation enzymes and risk of birth defects.

Associations between acute and long-term exposure to PM2.5 components and temperature with QT interval length in the VA Normative Aging Study.

A Sharp Decline in Burden of Stroke in Rural China During COVID-19 Pandemic.

Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort.

Outdoor air pollution and diminished ovarian reserve among infertile Korean women.

Air pollution exposure is linked with methylation of immunoregulatory genes, altered immune cell profiles, and increased blood pressure in children.

Lower-than-standard particulate matter air pollution reduced life expectancy in Hong Kong: A time-series analysis of 8.5 million years of life lost.

Exposure to chemical components of fine particulate matter and ozone, and placenta-mediated pregnancy complications in Tokyo: a register-based study.

Exposure to ambient particulate matter and biomass burning during pregnancy: associations with birth weight in Thailand.

Air Pollution and Polyclonal Elevation of Serum Free Light Chains: An Assessment of Adaptive Immune Responses in the Prospective Heinz Nixdorf Recall Study.

Association between ambient particulate matter exposure and platelet counts in adults: a retrospective cohort study.

Long-Term Exposure to PM2.5 and Cognitive Decline: A Longitudinal Population-Based Study.

Prenatal PM_2.5 exposure and neurodevelopment at 2 years of age in a birth cohort from Mexico city.

Differences in environmental factors contributing to preterm labor and PPROM – population based study.

Acute effects of air pollution on lupus nephritis in patients with systemic lupus erythematosus: A multicenter panel study in China.

Association between Ambient Air Pollution and County-Level Cardiovascular Mortality in the United States by Social Deprivation Index.

INSIDE Project: Individual Air Pollution Exposure, Extracellular Vesicles Signaling and Hypertensive Disorder Development in Pregnancy.

COVID-19 Higher Mortality in Chinese Regions With Chronic Exposure to Lower Air Quality.

Miscellaneous

Effects of a Lifestyle Change Intervention on Semen Quality in Healthy Young Men Living in Highly Polluted Areas in Italy: The FASt Randomized Controlled Trial.

Laboratory Studies

BPA/Phenols

Low-dose Bisphenol A and its analogues Bisphenol F and S activate estrogen receptor ß and slightly modulate genes in human gingival keratinocytes.

Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding.

Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts.

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells.

Growth and reproduction effects and transgenerational effects of nonylphenol in Moina mongolica Daday (Crustacea: Cladocera).

Probing the toxic interactions between bisphenol A and glutathione S-transferase Phi8 from Arabidopsis thaliana.

Structural and chemical role of mesenchymal stem cells and resveratrol in regulation of apoptotic -induced genes in Bisphenol-A induced uterine damage in adult female albino rats.

Epigenetic biomarkers as tools for chemical hazard assessment: Gene expression profiling using the model Danio rerio. [BPA]

Phthalates

Comparative Effects of Di-(2-ethylhexyl)phthalate and Di-(2-ethylhexyl)terephthalate Metabolites on Thyroid Receptors: In Vitro and In Silico Studies.

Parabens/Triclosan/Antimicrobials

Sublethal and environmentally relevant concentrations of triclosan and triclocarban induce histological, genotoxic, and embryotoxic effects in Clarias gariepinus (Burchell, 1822).

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Mixtures of persistent organic pollutants increase ovarian granulosa tumor cell line migration and spheroid invasion by upregulating MMP2 expression and activity via IGF1R.

Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice.

Lycopene ameliorates the effect of Aroclor 1254 on morphology, proliferation, and angiogenesis of the thyroid gland in rat.

Perfluoroalkyl Substances

Developmental exposures to perfluorooctanesulfonic acid (PFOS) impact embryonic nutrition, pancreatic morphology, and adiposity in the zebrafish, Danio rerio.

Effects of in vitro exposure of perfluorooctanoic acid and monocrotophos on astroglia SVG p12 cells.\

Soil acidification enhancing the growth and metabolism inhibition of PFOS and Cr(VI) to bacteria involving oxidative stress and cell permeability.

Flame Retardants

Short-term exposure of decabromodiphenyl ether in female adult Balb/c mice: immune toxicity and self-recovery.

Low Dose of Fire Retardant, 2,2′,4,4′-Tetrabromodiphenyl ether (BDE47), stimulates the proliferation and differentiation of progenitor Leydig cells of male rats during prepuberty.

Exposure to 4-bromodiphenyl ether during pregnancy blocks testis development in male rat fetuses.

Insight into the mechanism of tetrachlorobisphenol A (TCBPA)-induced proliferation of breast cancer cells by GPER-mediated signaling pathways.

Different co-culture models reveal the pivotal role of TBBPA-promoted M2 macrophage polarization in the deterioration of endometrial cancer.

Pesticides

Effects of in utero and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid clothianidin on the reproductive organs of female mice.

Demystifying Chronic Kidney Disease of Unknown Etiology (CKDu): Computational Interaction Analysis of Pesticides and Metabolites with Vital Renal Enzymes.

Iprodione and chlorpyrifos induce testicular damage, oxidative stress, apoptosis and suppression of steroidogenic- and spermatogenic-related genes in immature male albino rats.

Modeling acetylcholine esterase inhibition resulting from exposure to a mixture of atrazine and chlorpyrifos using a physiologically-based kinetic model in fish.

Insights into the degradation and toxicity difference mechanism of neonicotinoid pesticides in honeybees by mass spectrometry imaging.

The development of the solitary bee Osmia bicornis is affected by some insecticide agrochemicals at environmentally relevant concentrations.

Acute exposure to fipronil induces oxidative stress, apoptosis and impairs epithelial homeostasis in the midgut of the stingless bee Partamona helleri Friese (Hymenoptera: Apidae).

Endocrine Disruptor Exposure Causes Infochemical Dysregulation and an Ecological Cascade from Zooplankton to Algae.

Effects of chlorpyrifos exposure on liver inflammation and intestinal flora structure in mice.

Protective effect of melatonin against herbicides-induced hepatotoxicity in rats.

Potentially Toxic Elements

A Single Microbiome Gene Alters Murine Susceptibility to Acute Arsenic Exposure.

Neurobehavioral and neurochemical effects in rats offspring co-exposed to arsenic and fluoride during development.

Microplastics

Photolytic degradation elevated the toxicity of polylactic acid microplastics to developing zebrafish by triggering mitochondrial dysfunction and apoptosis.

Air Pollution

Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice.

Traffic generated emissions alter the lung microbiota by promoting the expansion of Proteobacteria in C57Bl/6 mice placed on a high-fat diet.

Parental PM₂ _.5 exposure changes Th17/Treg cells in offspring, is associated with the elevation of blood pressure.

Pharmaceuticals/Personal Care Products

Classical toxicity endpoints in female rats are insensitive to the human endocrine disruptors diethylstilbestrol and ketoconazole.

Metabolomics reveals the reproductive abnormality in female zebrafish exposed to environmentally relevant levels of climbazole.

Paternal exposure to a common pharmaceutical (Ritalin) has transgenerational effects on the behaviour of Trinidadian guppies.

Mixtures

Comparing the effects of an exposure to a polycyclic aromatic hydrocarbon mixture versus individual polycyclic aromatic hydrocarbons during monocyte to macrophage differentiation: Mixture exposure results in altered immune metrics.

Toxicity of binary mixtures of pesticides and pharmaceuticals toward Vibrio fischeri: Assessment by quantitative structure-activity relationships.

Microplastics, chlorpyrifos and their mixtures modulate immune processes in the terrestrial crustacean Porcellio scaber.

More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells.

Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism.

Arsenic exposure combined with nano- or microplastic induces different effects in the marine rotifer Brachionus plicatilis.

Miscellaneous

Developmental Programming: Metabolic Tissue-Specific Changes in Endoplasmic Reticulum Stress, Mitochondrial Oxidative and Telomere Length Status induced by Prenatal Testosterone Excess in the Female Sheep.

Exposure/Environment Studies

Numerous Chemicals

Temporal exposure and consistency of endocrine disrupting chemicals in a longitudinal study of individuals with impaired fasting glucose. [bisphenols, phthalates, parabens]

First screening of biocides, persistent organic pollutants, pharmaceutical and personal care products in Antarctic phytoplankton from Deception Island by FT-ICR-MS.

Associations between perfluoroalkyl acids in serum and lead and mercury in whole blood among US children aged 3-11 years.

BPA/Phenols

Effects of a Plastic-Free Lifestyle on Urinary Bisphenol A Levels in School-Aged Children of Southern Italy: A Pilot Study.

Occurrence of Bisphenols and Benzophenone UV Filters in White-Tailed Eagles (Haliaeetus albicilla) from Smøla, Norway.

Phthalates

Evaluating inter-study variability in phthalate and trace element analyses within the Children’s Health Exposure Analysis Resource (CHEAR) using multivariate control charts.

Prevalence of phthalate alternatives and monoesters alongside traditional phthalates in indoor dust from a typical e-waste recycling area: Source elucidation and co-exposure risk.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Biomonitoring of the adult population living near the waste incinerator of Turin: Serum concentrations of PCDDs, PCDFs, and PCBs after three years from the plant start-up.

Sustained bloodstream release of persistent organic pollutants induced by extensive weight loss after bariatric surgery: Implications for women of childbearing age.

Health risks of exposure to soil-borne dichlorodiphenyltrichloroethanes (DDTs): A preliminary probabilistic assessment and spatial visualization.

Potential health risk assessment of HFRs, PCBs, and OCPs in the Yellow River basin.

Exposure to DDT and HCH congeners and associated potential health risks through khat (Catha edulis) consumption among adults in South Wollo, Ethiopia.

Interspecific and intraspecific variation in organochlorine pesticides and polychlorinated biphenyls using non-destructive samples from Pygoscelis penguins.

Endocrine-disrupting organochlorine xenobiotics in fish products imported from Asia-an assessment of human health risk.

Flounders as indicators of environmental contamination by persistent organic pollutants and health risk.

Perfluoroalkyl Substances

Per- and Polyfluoroalkyl Substances in Human Serum Samples of Selected Populations from Ghana.

Occurrence of perfluorinated carboxylic acids in Mexico City’s wastewater: A monitoring study in the sewerage and a mega wastewater treatment plant.

Migration histories and perfluoroalkyl acid (PFAA) loads in an estuarine fish: A novel union of analyses to understand variation in contaminant concentrations.

Per- and polyfluoroalkyl substances in surface water, gas and particle in open ocean and coastal environment.

Flame Retardants

Levels of Polybrominated Diphenyl Ethers in Brazilian Food of Animal Origin and Estimation of Human Dietary Exposure.

Brominated flame retardants (BFRs) in marine food webs from Bohai Sea, China.

Decabromodiphenylether trends in the European environment: Bird eggs, sewage sludge and surficial sediments.

Assessment of polybrominated diphenyl ethers and emerging brominated flame retardants in Pheretima (a Traditional Chinese Medicine): Occurrence, residue profiles, and potential health risks.

Pesticides

Comparison of cumulative dietary exposure to pesticide residues for the reference periods 2014-2016 and 2016-2018.

Concentrations of urinary biomarkers and predictors of exposure to pyrethroid insecticides in young, Polish, urban-dwelling men.

Relation between organophosphate pesticide metabolite concentrations with pesticide exposures, SOCIO-ECONOMIC factors and lifestyles: A cross-sectional study among school BOYS IN the rural western cape, South Africa.

Profiles of neonicotinoid insecticides and characteristic metabolites in paired urine and blood samples: Partitioning between urine and blood and implications for human exposure.

Assessment of risk to honey bees and honey consumers resulting from the insect exposure to captan, thiacloprid, penthiopyrad, and λ-cyhalothrin used in a commercial apple orchard.

Population decline in a ground-nesting solitary squash bee (Eucera pruinosa) following exposure to a neonicotinoid insecticide treated crop (Cucurbita pepo).

Monarch Butterfly (Danaus plexippus) Life Stage Risks from Foliar and Seed-Treatment Insecticides.

Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides.

Potentially Toxic Elements

Public-health risks from tea drinking: Fluoride exposure.

Dietary Fluoride Intake Over the Course of Pregnancy in Mexican Women.

The burden of disease of three food-associated heavy metals in clusters in the Danish population – towards targeted public health strategies.

Mercury in the human thyroid gland: Potential implications for thyroid cancer, autoimmune thyroiditis, and hypothyroidism.

Total blood mercury and its determinants in New Zealand children and adults.

Arsenic, Cadmium, Lead, and Mercury in Lactation Foods and Prenatal Vitamins: Potentially Avoidable Exposure for Breastfeeding Mothers and Infants.

Urinary arsenic species and methylation efficiency during pregnancy: concentrations and associated factors in Spanish pregnant women.

Walrus teeth as biomonitors of trace elements in Arctic marine ecosystems.

Comparing impacts of metal contamination on macroinvertebrate and fish assemblages in a northern Japanese river.

Recent Advances in Nanotechnology-Based Biosensors Development for Detection of Arsenic, Lead, Mercury, and Cadmium. [review]

Health risks of arsenic buildup in soil and food crops after wastewater irrigation.

Chronic exposure to trace lead impairs honey bee learning.

Mercury biomagnification in a Southern Ocean food web.

Intake of food supplements based on algae or cyanobacteria may pose a health risk due to elevated concentrations of arsenic species.

Microplastics

Plastic ingestion by marine fish is widespread and increasing.

Fate of floating plastic debris released along the coasts in a global ocean model.

Air Pollution

PM2.5 Concentration and Composition in Subway Systems in the Northeastern United States

Health risk assessment of volatile organic compounds at daycare facilities.

Pharmaceuticals/Personal Care Products

A review of distribution and risk of pharmaceuticals and personal care products in the aquatic environment in China.

Cross-tracking of faecal pollution origins, macronutrients, pharmaceuticals and personal care products in rural and urban watercourses.

Miscellaneous

ANN-Based Integrated Risk Ranking Approach: A Case Study of Contaminants of Emerging Concern of Fish and Seafood in Europe.

Mapping multiple endocrine disrupting activities in Virginia rivers using effect-based assays.

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sa…@healthandenvironment.org and ask to join the group EDC_re…@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Feel free to forward. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

If you enjoy this newsletter, please feel free to donate here! Thank you!

EHN EHN

Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.
Lou Guillette Jr. Memorial Symposium
by Sarah Howard on October 22, 2024 at 1:30 pm
On March 14-15, 2025, HEEDS is hosting the Lou Guillette Jr. Memorial Symposium on endocrine disrupting science at the University of Florida. It will celebrate the life and legacy of Dr. Guillette, gather together his trainees and colleagues, and focus on the research topics that Lou made famous. Information here.
Webinar: The overturning of Chevron deference: impacts on environmental health decision making
by Sarah Howard on October 17, 2024 at 4:21 pm
In this Nov. 13 webinar, legal experts will discuss the implications of the overturning of Chevron deference and its profound impact on science, public health and decision-making. Sponsored by CHE and UCSF's EaRTH Center.

EHN EHN

Ultra-processed foods and plastic packaging make for the ultimate toxic pair, scientists say
by Katherine McMahon,Sarah Howard on October 25, 2024 at 10:37 am
A recent paper published in Globalization and Health explores the relationship between ultra-processed foods (UPFs), plastic packaging, and their combined threat to public health. “Consumers do not have the power to solve a problem of this scale, and thus it is the responsibility of policymakers to ensure that transitions away from unhealthy, unsustainable foods are accompanied by structural measures that support demand and access to healthy foods.”
Microplastic exposure linked to reduced sperm quality in humans
by Katherine McMahon,Sarah Howard on October 23, 2024 at 4:29 pm
Exposure to microplastics is associated with a decrease in sperm concentration, motility, and shape, according to a new study published in The Lancet. “The identification of non-stick pan coating material PTFE as a particularly hazardous microplastic for male fertility underscores the importance of targeted interventions to reduce exposure to this and similar substances.”
Exposure to PFAS in ski wax may be linked to high cholesterol
by Katherine McMahon,Sarah Howard on October 16, 2024 at 7:42 pm
According to a new study published in Environmental Research, skiers and snowboarders may face health risks from their exposure to PFAS via ski wax, which can contain up to 100% PFAS by mass. “Interventions to remove PFAS from fluorinated wax could decrease direct exposure to skiers and reduce PFAS release into the environment.”

EHN EHN

Stricter toxic chemical rules reduce Californians’ exposures
by Kristina Marusic on October 31, 2024 at 11:25 am
Californians have lower levels of toxic chemicals linked to cancer, birth defects and reproductive harm in their bodies than people in the rest of the country, according to a new study. The study, published in Environmental Health Perspectives and conducted by researchers at Silent Spring Institute, a nonprofit scientific research organization, and the University of California at Berkeley (UC Berkeley), looked at nationwide data on the levels of 37 toxic chemicals in people’s blood before and after California introduced its stringent regulations. It found that for 18 of these chemicals, Californians have lower levels in their bodies than the rest of the country.
EPA dismissed data on the neurotoxicity of common insecticides
by Katherine McMahon,Sarah Howard on October 30, 2024 at 5:56 pm
A recent paper in Frontiers in Toxicology examined research submitted by industry to the U.S. Environmental Protection Agency (EPA) on the neurotoxicity of neonicotinoids - the most widely used class of insecticides in the U.S. and worldwide - and found that the data was evaluated improperly by the agency. Why this matters: Neonicotinoids are widely used not only for commercial agriculture but also for more personal uses like home gardens and in some flea and tick treatments for pets. Humans are regularly exposed to neonicotinoids – which are structurally similar to nicotine – through the environment, food and water. Neonicotinoids’ popularity partly comes from the belief that their harmful effects are mostly limited to insects, but studies like this one demonstrate that mammals may also be harmed by the chemicals, and highlight the urgent need for stronger regulations around their use.
Pesticide regulations ignore critical threats to insect health and ecosystems
by EHN Curators on October 30, 2024 at 10:26 am
In a study revealing regulatory gaps, researchers found that pesticides impact insect behavior and survival at non-lethal doses, especially in warmer temperatures, calling into question the effectiveness of current pesticide safety protocols. Dave Goulson writes for The Conversation.