HEEDS works with scientists around the world to publish important articles on endocrine disrupting chemicals (EDCs). Dr. Jerry Heindel has published over 100 articles over the years and coordinates and contributes to numerous articles with co-authors. This page includes:
- Publications by HEEDS
- Consensus Statements on EDCs
- Important Reviews and Commentaries
- Important Books on EDCs
For updates on new EDC science, see our New EDC Science page, EDC Science Weekly, or Research Roundup on Metabolism Disruptors newsletter.
Publications by HEEDS
Obesogen Reviews
HEEDS coordinated and published three comprehensive review articles on obesogens, coauthored by dozens of experts in the field. They are open access.
- Obesity I: Overview and molecular and biochemical mechanisms
- Obesity II: Establishing causal links between chemical exposures and obesity
- Obesity III: Obesogen assays: limitations, strengths, and new directions
They are published in the journal Biomedical Pharmacology as part of a special issue, Impact of Endocrine Disrupting Chemicals on Health and Disease. Also see the related article in The Guardian, Environmental toxins are worsening obesity pandemic, say scientists, by Damian Carrington.
We also organized a workshop on obesogens at the Wingspread conference center, summarized here:
Obesogens and obesity: State-of-the-science and future directions summary from a Healthy Environment and Endocrine Disruptors Strategies workshop.
Heindel JJ, Alvarez JA, Atlas E, Cave MC, et al. Am J Clin Nutr. 2023 Jul;118(1):329-337.
Additional Articles by HEEDS staff
Obesogens: a unifying theory for the global rise in obesity.
Heindel JJ, Lustig RH, Howard S, Corkey BE. Int J Obes (Lond). 2024 Apr;48(4):449-460.
History of the obesogen field: looking back to look forward.
Heindel JJ. Front Endocrinol (Lausanne). 2019 Jan 29;10:14. doi: 10.3389/fendo.2019.00014. PMID: 30761083; PMCID: PMC6362096.
Interventions to address environmental metabolism-disrupting chemicals: changing the narrative to empower action to restore metabolic health.
Sargis RM, Heindel JJ, Padmanabhan V. Front Endocrinol (Lausanne). 2019 Feb 4;10:33.
Exposure to environmental chemicals and type 1 diabetes: an update.
Howard SG. J Epidemiol Community Health. 2019 Jun;73(6):483-488. doi: 10.1136/jech-2018-210627. Epub 2019 Mar 12. PMID: 30862699.
Developmental exposure to endocrine disrupting chemicals and type 1 diabetes mellitus.
Howard SG. Front Endocrinol (Lausanne). 2018 Sep 3;9:513. doi: 10.3389/fendo.2018.00513. PMID: 30233498; PMCID: PMC6129584.
Consensus Statements on EDCs
EDC-2: The Endocrine Society’s second scientific statement on endocrine-disrupting chemicals
Gore AC, Chappell VA, Fenton SE et al. Endocrine Reviews 2015 Dec;36(6):E1-E150.
EDC-2 executive summary
The first Endocrine Society scientific statement on EDCs (2009)
Impacts of food contact chemicals on human health: a consensus statement.
Muncke J, Andersson AM, Backhaus T, Boucher JM, et al. Environ Health. 2020 Mar 3;19(1):25.
The International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals
Di Renzo GC, Conry JA, Blake J et al.
Int J Gynaecol Obstet. 2015 Dec;131(3):219-25.
The American College of Obstetricians and Gynecologists: committee opinion on reducing prenatal exposure to toxic environmental agents
2013; Reaffirmed 2018, 2024.
Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement
Solecki R, Kortenkamp A, Bergman Å et al.
Arch Toxicol. 2017 Feb;91(2):1001-1006.
Uppsala consensus statement on environmental contaminants and the global obesity epidemic.
Lind L, Lind PM, et al. Environ Health Perspect. 2016 May 1;124(5):A81-3.
Parma consensus statement on metabolic disruptors.
Heindel JJ, Vom Saal FS, et al. Environ Health. 2015 Jun 20;14:54.
Reviews and Commentaries on EDCs
Articles
A vision for safer food contact materials: public health concerns as drivers for improved testing.
Muncke J, Andersson AM, Backhaus T, Belcher SM, et al. Environ Int. 2023 Oct;180:108161.
The conflict between regulatory agencies over the 20,000-fold lowering of the Tolerable Daily Intake (TDI) for bisphenol A (BPA) by the European Food Safety Authority (EFSA).
Vom Saal et al. Environ Health Perspect. 2024 Apr;132(4):45001.
Chemicals used in plastic materials: an estimate of the attributable disease burden and costs in the United States.
Trasande L, Krithivasan R, Park K, Obsekov V, Belliveau M. J Endocr Soc. 2024 Jan.
From Wingspread to CLARITY: a personal trajectory.
Soto AM, Schaeberle CM, Sonnenschein C.
Nat Rev Endocrinol. 2021 Jan 29.
Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies.
Heindel JJ, Belcher S, Flaws JA, Prins GS, et al. Reprod Toxicol. 2020 Dec;98:29-60.
Endocrine disruptors: from scientific evidence to human health protection
Demeneix B and Slama R.
Report for the European Parliament, 2019.
A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals
Vandenberg LN, Ågerstrand M, Beronius A et al.
Environ Health. 2016 Jul 14;15(1):74.
Minireview: endocrine disruptors: past lessons and future directions
Schug TT, Johnson AF, Birnbaum LS et al.
Mol Endocrinol. 2016 Aug;30(8):833-47.
Peer-reviewed and unbiased research, rather than ‘sound science’, should be used to evaluate endocrine-disrupting chemicals
Trasande L, Vandenberg LN, Bourguignon JP et al.
J Epidemiol Community Health. 2016 Nov;70(11):1051-1056.
Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European Union
Trasande L, Zoeller RT, Hass U et al.
J Clin Endocrinol Metab. 2015 Apr;100(4):1245-55.
Designing endocrine disruption out of the next generation of chemicals
Schug TT, Abagyan R et al.
Green Chem. 2013 Jan;15(1):181-198.
Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology
Vandenberg LN, Colborn T, Hayes TB et al.
Reprod Toxicol. 2013 Jul;38:1-15.
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
Vandenberg LN, Colborn T, Hayes TB et al.
Endocr Rev. 2012 Jun;33(3):378-455.
Collections
Collection: Endocrine Disrupting Chemicals 2019, in The Endocrine Society Thematic Issue of Endocrine Society Journals.
Collection: Endocrine Disruption, in Nature Reviews Endocrinology, 2017.
Research Topic: Endocrine Disruptors and Metabolism, in Frontiers in Endocrinology, 2018-19.
Reports
Toxic Chemicals in Everyday Life
U.K. House of Commons Environmental Audit Committee
July 2019
The United Nations: Scientific Knowledge of Endocrine Disrupting Chemicals
Three reports on EDCs, on identifying EDCs, the environmental effects of EDCs, and global regulatory frameworks.
Books on EDCs
Newer Releases (2018-present)
Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race, by Dr. Shanna Swan and Stacey Colino, 2021.
The Monsanto Papers: Deadly Secrets, Corporate Corruption, and One Man’s Search for Justice, by Carey Gillam, 2021.
Non-Toxic: Guide to Living Healthy in a Chemical World, by Dr. Aly Cohen and Dr. Fred vom Saal
Sicker, Fatter, Poorer, by Dr. Leo Trasande, 2019.
Textbook of Children’s Environmental Health, 2nd edition, edited by Ruth A. Etzel and Philip J. Landrigan, 2024.
Children and Environmental Toxins: What Everyone Needs to Know®, by Philip J. Landrigan and Mary M. Landrigan, 2018.
The Classics
Our Stolen Future: Are We Threatening our Fertility, Intelligence, and Survival? A Scientific Detective Story, by Dr. Theo Colborn, Dr. John Peterson Myers, and Dianne Dumanoski, 1997.
Silent Spring, by Rachel Carson, 1962.
Additional Recommended Books
Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice, ed. Dr. Andrea Gore, 2007.
Endocrine Disruptors, Brain and Behavior, by Drs. Heather Patisaul and Scott Belcher, 2017.
Integrative Environmental Medicine, eds. Aly Cohen and Dr. Frederick vom Saal; series ed. Andrew Weil, 2017.
Losing Our Minds: How Environmental Pollution Impairs Human Intelligence and Mental Health, by Dr. Barbara Demeneix, 2014.
Only One Chance: How Environmental Pollution Impairs Brain Development — and How to Protect the Brains of the Next Generation, by Dr. Philippe Grandjean, 2015.
Plastic: A Toxic Love Story, by Susan Freinkel, 2011.
Slow Death by Rubber Duck: The Secret of Danger of Everyday Things, by Rick Smith and Bruce Lourie, 2011.
Toxic Cocktail: How Chemical Pollution is Poisoning our Brains, by Dr. Barbara Demeneix, 2017.