New EDC articles, Oct. 9 – 15, 2019 – HEEDS

New EDC articles, Oct. 9 – 15, 2019

Post author:HEEDS
Post published:October 15, 2019
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Methods/Screening, Reviews, Human Health Studies, Laboratory Studies, Human Exposure Studies, Wildlife/Environment Studies.

Methods/Screening

Deciphering adverse outcome pathway network linked to Bisphenol F using text mining and systems toxicology approaches.

Machine learning for mixture toxicity analysis based on high-throughput printing technology.

Dual stir bar sorptive extraction coupled to thermal desorption-gas chromatography-mass spectrometry for the determination of endocrine disruptors in human tissues.

Grouping of complex substances using analytical chemistry data

Molecular characterization of a toxicological tipping point during human stem cell differentiation.

Development of QSAAR and QAAR models for predicting fish early-life stage toxicity with a focus on industrial chemicals.

Reviews

Phthalates

Association between the exposure to phthalates and adiposity: A meta-analysis in children and adults.

Pesticides

The insect apocalypse, and why it matters.

Insect Declines in the Anthropocene.

Global Trends in Bumble Bee Health.

Bombus (Hymenoptera: Apidae) Microcolonies as a Tool for Biological Understanding and Pesticide Risk Assessment.

Comparative Assessment of Vegetative and Reproductive Terrestrial Plant Species Endpoints from Exposure to Herbicides and Potential Environmental Implications – a Literature Review.

Arsenic/Metals

Toenails as biomarker of exposure to essential trace metals: A review.

Arsenic exposure with reference to neurological impairment: an overview.

Air Pollution

Susceptibility Variations in Air Pollution Health Effects: Incorporating Neuroendocrine Activation.

Association between fire smoke fine particulate matter and asthma-related outcomes: Systematic review and meta-analysis.

Miscellaneous

Comparative assessment of the sensitivity of fish early-life stage, Daphnia and algae to the chronic ecotoxicity of xenobiotics – perspectives for alternatives to animal testing.

Pruning chemicals from the green building landscape.

Human Health Studies

BPA/Phenols

Adipose tissue concentrations of non-persistent environmental phenols and local redox balance in adults from Southern Spain.

Phthalates/Parabens

Tumor expression of environmental chemical-responsive genes and breast cancer mortality.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins.

Polychlorinated biphenyl exposure and DNA methylation in the Anniston Community Health Survey.

Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study.

Perfluoroalkyl Substances

Perfluoroalkyl substances and changes in bone mineral density: A prospective analysis in the POUNDS-LOST study.

Pesticides

Residential proximity to greenhouse agriculture and neurobehavioral performance in Ecuadorian children.

[Effects of methylenetetrahydrofolate reductase gene polymorphism and long-term exposure to organophosphorus pesticides on type 2 diabetes mellitus]. [In Chinese]

Arsenic/Metals

Association Between Maternal Exposure to Lead, Maternal Folate Status, and Intergenerational Risk of Childhood Overweight and Obesity

Cumulative Childhood Lead Levels in Relation to Sleep During Adolescence.

Prenatal lead exposure, type 2 diabetes and cardiometabolic risk factors in Mexican children at age 10-18 years.

Roles of C-reactive protein on the association between urinary cadmium and type 2 diabetes.

Association between heavy metals and metalloids in topsoil and mental health in the adult population of Spain.

Trace elements in saliva and plasma of patients with type 2 diabetes: Association to metabolic control and complications.

Air Pollution

Air Pollution, Clustering of Particulate Matter Components, and Breast Cancer in the Sister Study: A U.S.-Wide Cohort.

Early Life Exposure to Air Pollution and Autism Spectrum Disorder: Findings from a Multisite Case-Control Study.

Exposure to Ambient Air Pollution and Cognitive Impairment in Community-Dwelling Older Adults: The Korean Frailty and Aging Cohort Study.

Gestational diabetes mellitus, prenatal air pollution exposure, and autism spectrum disorder.

Miscellaneous

Internal biomarkers and external estimation of exposure to polycyclic aromatic hydrocarbons and their relationships with cancer mortality in a high cancer incidence area.

Laboratory Studies

BPA/Phenols

Bisphenol AF promotes inflammation in human white adipocytes.

Maternal exposure to bisphenol A during pregnancy interferes ovaries development of F1 female mice.

Memory Function, Neurological, and Immunological Biomarkers in Allergic Asthmatic Mice Intratracheally Exposed to Bisphenol A.

Global and region-specific post-transcriptional and post-translational modifications of bisphenol A in human prostate cancer cells.

Perinatal exposure to bisphenol A (BPA) impairs neuroendocrine mechanisms regulating food intake and kisspetin system in adult male rats. Evidences of metabolic disruptor hypothesis.

DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer.

Phthalates

Effect of subacute and prenatal DINCH plasticizer exposure on rat dams and male offspring hepatic function: The role of PPAR-α. [phthalate replacement]

Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus.

Perfluoroalkyl Substances

Bioconcentration and metabolic effects of emerging PFOS alternatives in developing zebrafish.

Flame Retardants

[Effect of prenatal BDE-99 exposure on the maternal thyroid hormones levels and development of rat offspring]. [In Chinese]

Organotins

Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish.

Pesticides

In vitro and in vivo endocrine disrupting effects of the azole fungicides triticonazole and flusilazole.

In silico evaluation of pesticides as potential modulators of human DNA methyltransferases.

Toxicity of microbial insecticides towards the non-target freshwater insect Chironomus xanthus.

Identification of signal pathways for immunotoxicity in the spleen of common carp exposed to chlorpyrifos.

Effects of insecticides, fipronil and imidacloprid, on the growth, survival, and behavior of brown shrimp Farfantepenaeus aztecus.

Gonadal disruption after single dose exposure of prothioconazole and prothioconazole-desthio in male lizards (Eremias argus).

Paraquat exposure delays late-stage Leydig cell differentiation in rats during puberty.

Glyphosate but not Roundup® harms earthworms (Eisenia fetida).

Dimethoate blocks pubertal differentiation of Leydig cells in rats.

Intracerebroventricular injection of deltamethrin increases locomotion activity and causes spatial working memory and dopaminergic pathway impairment in rats.

Do you smell the danger? Effects of three commonly used pesticides on the olfactory-mediated antipredator response of zebrafish (Danio rerio).

Arsenic/Metals

Rapid screening for ecotoxicity of plating and semiconductor wastewater employing the heartbeat of Daphnia magna.

Arsenite exposure suppresses adipogenesis, mitochondrial biogenesis and thermogenesis via autophagy inhibition in brown adipose tissue.

Pxr- and Nrf2- mediated induction of ABC transporters by heavy metal ions in zebrafish embryos.

Mercury chloride exposure induces DNA damage, reduces fertility, and alters somatic and germline cells in Drosophila melanogaster ovaries.

Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach.

Effect of arsenic and/or fluoride gestational exposure on renal autophagy in offspring mice.

Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals.

Might the interspecies interaction between fish and shrimps change the pattern of their avoidance response to contamination?

Microplastics

Decreased growth and survival in small juvenile fish, after chronic exposure to environmentally relevant concentrations of microplastic.

Effects of microplastic particles and leaching additive on the life history and morphology of Daphnia magna. [includes leaching of phthalates]

Air Pollution

Exposure to atmospheric pollutants is associated with alterations of gut microbiota in spontaneously hypertensive rats.

Pharmaceuticals

SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer latency following developmental estrogenic chemical exposure. [DES]

Fluoxetine Exposure During Sexual Development Disrupts the Stress Axis and Results in Sex- and Time- Dependent Effects on the Exploratory Behavior in Adult Zebrafish Danio rerio.

Analysis of tail coiling activity of zebrafish (Danio rerio) embryos allows for the differentiation of neurotoxicants with different modes of action. [pharmaceuticals, cadmium, pesticides]

Mixtures

Combination of fluoride and endosulfan induced teratogenicity and developmental toxicity in Swiss albino mice exposed during organogenesis.

Combined anti-androgenic effects of mixtures of agricultural pesticides using in vitro and in silico methods.

Roles of mtDNA damage and disordered Ca2+ homeostasis in the joint toxicities of cadmium and BDE209.

Miscellaneous

Transfer and Metabolism of the Xenoestrogen Zearalenone in Human Perfused Placenta.

Genistein Inhibits Proliferation and Induces Senescence in Neonatal Mouse Pituitary Gland Explant Cultures.

Exposure to chemically-dispersed oil is more harmful to early developmental stages of the Northern shrimp Pandalus borealis than mechanically-dispersed oil.

Human Exposure Studies

BPA/Phenols

Empirical models to predict the effect of sterilisation and storage on bisphenols migration from metallic can coatings into food simulants.

Phthalates

Diminution of migration of phthalic acid esters in tequila beverage by the year of production.

Perfluoroalkyl Substances

Dietary Habits Related to Food Packaging and Population Exposure to PFASs.

Flame Retardants

Geographical distributions and human exposure of organophosphate esters in college library dust from Chinese cities.

Emissions and Occupational Exposure Risk of Halogenated Flame Retardants from Primitive Recycling of E-Waste.

Arsenic/Metals

A pilot study of mothers and infants reveals fetal sex differences in the placental transfer efficiency of heavy metals.

Mercury exposure, risk factors, and perceptions among women of childbearing age in an artisanal gold mining region of the Peruvian Amazon.

Chemical imaging and assessment of cadmium distribution in the human body.

China’s Ban on Phenylarsonic Feed Additives, A Major Step towards Reducing the Human and Ecosystem Health Risk from Arsenic.

Human health risk assessment of exposure to indoor mercury vapour in a Ghanaian artisanal small-scale gold mining community.

A Reversible Case of Chronic Arsenicosis due to Homeopathy Medicine.

Hazardous heavy metals contamination of vegetables and food chain: Role of sustainable remediation approaches – A review.

Air Pollution

The use of personal and indoor air pollution monitors in reproductive epidemiology studies.

Wildlife/Environment Studies

BPA/Phenols

Combined study of source, environmental monitoring and fate of branched alkylphenols: The chain length matters.

Parabens/Triclosan/Antimicrobials

Occurrence, seasonal variation and risk evaluation of selected endocrine disrupting compounds and their transformation products in Jiulong river and estuary, China.

Persistent Organic Pollutants: PCBs, Dioxin, OCPs

Persistent organic pollutants in blubber of fin whales (Balaenoptera physalus) from the Southern Ocean.

Trace metals and persistent organic pollutants fingerprint on the particle flux in the deep subtropical NE Atlantic.

Associations between organohalogen exposure and thyroid- and steroid-related gene responses in St. Lawrence Estuary belugas and minke whales.

Persistent organic pollutants (POPs) in oriental magpie-robins from e-waste, urban, and rural sites: Site-specific biomagnification of POPs.

PCDD/PCDFs and PCBs in the irrigation water in Egypt: levels, patterns, and potential sources.

Historical sedimentary deposition and flux of PAHs, PCBs and DDTs in sediment cores from the western Adriatic Sea.

Perfluoroalkyl Substances

Make polluters pay for fluorochemical clean-up. [Letter in Nature] Comment on News item: Tainted water: the scientists tracing thousands of fluorinated chemicals in our environment

White-Tailed Eagle (Haliaeetus albicilla) Body Feathers Document Spatiotemporal Trends of Perfluoroalkyl Substances in the Northern Environment.

Temporal Trends (1981-2013) of per- and polyfluoroalkyl substances and total fluorine in Baltic cod (Gadus morhua).

[The invisible venom: the story of the contamination from PFAS (perfluoroalchilic substances) in the Veneto Region]. [in Italian]

Flame Retardants

Determination of human metabolites of chlorinated phosphorous flame retardants in wastewater by N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide-derivatization and gas chromatography-high resolution mass spectrometry.

Pesticides

Bee pollination outperforms pesticides for oilseed crop production and profitability.

Glyphosate and aminomethylphosphonic acid (AMPA) are commonly found in urban streams and wetlands of Melbourne, Australia.

Arsenic/Metals

Concentration, fluxes, risks, and sources of heavy metals in atmospheric deposition in the Lihe River watershed, Taihu region, eastern China.

Assessment of source and health risk of metal(loid)s in indoor/outdoor dust of university dormitory in Lanzhou City, China.

Health Risk Assessment of Heavy Metals and Lipid Quality Indexes in Freshwater Fish from Lakes of Warmia and Mazury Region, Poland.

Relationships between Pb, As, Cr, and Cd in individual cows’ milk and milk composition and heavy metal contents in water, silage, and soil.

A case study on pollution and a human health risk assessment of heavy metals in agricultural soils around Sinop province, Turkey.

Mobility, bioaccessibility and toxicity of potentially toxic elements in a contaminated soil treated with municipal solid waste compost.

Pollution evaluation and health risk assessment of airborne toxic metals in both indoors and outdoors of the Pearl River Delta, China.

A 300-year high-resolution Greenland ice record of large-scale atmospheric pollution by arsenic in the Northern Hemisphere.

Microplastics

The ocean’s ultimate trashcan: Hadal trenches as major depositories for plastic pollution.

Adhesion to coral surface as a potential sink for marine microplastics.

Massive plastic pollution in a mega-river of a developing country: Sediment deposition and ingestion by fish (Prochilodus lineatus).

Superimposed microplastic pollution in a coastal metropolis.

Pathway, classification and removal efficiency of microplastics in wastewater treatment plants. [review]

Marine Debris Polymers on Main Hawaiian Island Beaches, Sea Surface, and Seafloor.

Occurrence of tire wear particles and other microplastics within the tributaries of the Charleston Harbor Estuary, South Carolina, USA.

Can the Atlantic ghost crab be a potential biomonitor of microplastic pollution of sandy beaches sediment?

Distribution and impacts of microplastic incorporation within sea ice.

Piece-by-piece analysis of additives and manufacturing byproducts in plastics ingested by seabirds: Implication for risk of exposure to seabirds.

Making citizen science count: Best practices and challenges of citizen science projects on plastics in aquatic environments.

and many more like this in Marine Pollution Bulletin

Air Pollution

Annual changes in concentrations and health risks of PCDD/Fs, DL-PCBs and organochlorine pesticides in ambient air based on the Global Monitoring Plan in São Paulo.

Pharmaceuticals

Simultaneous determination of new psychoactive substances and illicit drugs in sewage: Potential of micro-liquid chromatography tandem mass spectrometry in wastewater-based epidemiology.

An evidence synthesis of pharmaceuticals and personal care products (PPCPs) in the environment: imbalances among compounds, sewage treatment techniques, and ecosystem types.

Mixtures

Persistent and substantial impacts of the Deepwater Horizon oil spill on deep-sea megafauna.

Miscellaneous

Endocrine and reproductive endpoints of Notothenia rossii and N. coriiceps: A baseline study for ecotoxicological monitoring in Antarctic waters.

YestroSens, a field-portable S. cerevisiae biosensor device for the detection of endocrine-disrupting chemicals: Reliability and stability.

New insights into the responses of soil microorganisms to polycyclic aromatic hydrocarbon stress by combining enzyme activity and sequencing analysis with metabolomics.

Cleaning up plastic pollution in Africa. Perspective in Science

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This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. To see the searchable archives, please email me at Sarah@healthandenvironment.org and ask to join the group EDC_research@googlegroups.com. Archives are at https://groups.google.com/d/forum/edc_research. Feel free to forward. Compiled by Sarah Howard, Diabetes and Environment Program and HEEDS at Commonweal.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.