New EDC articles, Mar. 27 – Apr. 2, 2019 – HEEDS

New EDC articles, Mar. 27 – Apr. 2, 2019

Post author:HEEDS
Post published:April 2, 2019
Post category:EDC Science Weekly

A summary of articles on endocrine disrupting chemicals (EDCs) added to PubMed this week.

Contents: Regulations/Policy, Reviews, Human Health Studies, Laboratory Studies, and Wildlife/Environment/Exposure Studies

Regulations/Policy

Regulating endocrine disruptors linked to cancer.

Regulatory assessment and risk management of chemical mixtures: challenges and ways forward.

Report from the BfR expert hearing on practicability of hormonal measurements: recommendations for experimental design of toxicological studies with integrated hormonal end points.

Evaluation of the avian acute oral and sub-acute dietary toxicity test for pesticide registration.

Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach.

Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across.

Establishing the relevance of endocrine-disrupting effects for nontarget vertebrate populations. and

Assessing the population relevance of endocrine disrupting effects for nontarget vertebrates exposed to plant protection products

Reviews

Oxidative Phosphorylation Impairment by DDT and DDE.

Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review.

[Environmental risk factors for asthma developement]. [in French]

Adaptive responses to low doses of radiation or chemicals: their cellular and molecular mechanisms.

Food components and environmental chemicals of inhibiting human placental aromatase.

Antibiotic pollution in surface fresh waters: Occurrence and effects.

Congenital anomalies in the offspring of occupationally exposed mothers: a systematic review and meta-analysis of studies using expert assessment for occupational exposures. [solvents, pesticides, metals]

BPA/Phenols/Phthalates

A Systematic Review of Exposure to Bisphenol A from Dental Treatment.

Metals/Arsenic/Fluoride

Role of cadmium and arsenic as endocrine disruptors in the metabolism of carbohydrates: Inserting the association into perspectives.

Human Health Studies

BPA/Phthalates

Elevated Urinary Bisphenol A Levels are Associated with Nonalcoholic Fatty Liver Disease among Adults in the United States.

Associations between prenatal exposure to bisphenol a and neonatal outcomes in a Taiwanese cohort study: Mediated through oxidative stress?

Early pregnancy exposure to endocrine disrupting chemical mixtures are associated with inflammatory changes in maternal and neonatal circulation. [phthalates, phenols, metals]

Persistent Organic Pollutants

Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study.

Perfluoroalkyl Substances

Perfluoroalkyl substances are inversely associated with coronary heart disease in adults with diabetes.

Pesticides

Non-Hodgkin lymphoma risk and organophosphate and carbamate insecticide use in the north American pooled project.

Modified CDKN2B (p15) and CDKN2A (p16) DNA methylation profiles in urban pesticide applicators.

Thyroid and reproductive hormones in relation to pesticide use in an agricultural population in Southern Brazil.

Arsenic/Metals

Toenail concentrations of trace elements and occupational history in pancreatic cancer.

Sex-specific effects of blood cadmium on thyroid hormones and thyroid function status: Korean nationwide cross-sectional study.

A spatial study of bladder cancer mortality and incidence in the contiguous US: 2000-2014. [arsenic]

Decreased erythrocyte CD44 and CD58 expression link e-waste Pb toxicity to changes in erythrocyte immunity in preschool children.

In-utero arsenic exposure and growth of infants from birth to 6 months of age: a prospective cohort study in rural Bangladesh

Mendelian randomization of inorganic arsenic metabolism as a risk factor for hypertension- and diabetes-related traits among adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort.

Fluoride exposure and pubertal development in children living in Mexico City.

Laboratory Studies

BPA/Phenols

Effects of Bauhinia forficata on glycaemia, lipid profile, hepatic glycogen content and oxidative stress in rats exposed to Bisphenol A.

Perinatal exposure to Bisphenol S (BPS) promotes obesity development by interfering with lipid and glucose metabolism in male mouse offspring.

Identification of in vitro effect of 4-octylphenol on the basal and human chorionic gonadotropin (hCG) stimulated secretion of androgens and superoxide radicals in mouse Leydig cells.

Investigating the in vitro metabolism of the dental resin monomers BisGMA, BisPMA, TCD-DI-HEA and UDMA using human liver microsomes and quadrupole time of flight mass spectrometry.

Phthalates

Di-(2-Ethylhexyl) Phthalate Promotes Release of Tissue Factor-Bearing Microparticles From Macrophages via the TGFβ1/Smad/PAI-1 Signaling Pathway.

Adenomatous polyposis coli as a predictor of environmental chemical-induced transgenerational effects related to male infertility.

Parabens/Triclosan/Antimicrobials

Comparative transcriptional analysis of methylparaben and propylparaben in zebrafish.

Persistent Organic Pollutants

Exposures to the environmental contaminants pentachlorophenol and dichlorodiphenyltrichloroethane increase production of the proinflammatory cytokine, interleukin-1β, in human immune cells.

Assessment of epigenetic changes and oxidative DNA damage in rat pups exposed to polychlorinated biphenyls and the protective effect of curcumin in the prenatal period.

Prenatal toxicity and maternal-fetal distribution of 1,3,5,8-tetrachloronaphthalene (1,3,5,8-TeCN) in Wistar rats.

Evaluation of the oxidative stress in liver of crucian carp (Carassius auratus) exposed to 3,4,4′-tri-CDE, 2-MeO-3′,4,4′-tri-CDE, and 2-HO-3′,4,4′-tri-CDE.

Overexpression of cerebral cytochrome P450s in prenatally exposed offspring modify the toxicity of lindane in rechallenged offspring.

Perfluoroalkyl Substances

Adverse Maternal, Fetal, and Postnatal Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) from Oral Gestational Exposure in Sprague-Dawley Rats.

Chronic exposure to 6:2 chlorinated polyfluorinated ether sulfonate acid (F-53B) induced hepatotoxic effects in adult zebrafish and disrupted the PPAR signaling pathway in their offspring.

Characterization of non-radiolabeled Thyroxine (T4) uptake in cryopreserved rat hepatocyte suspensions: Pharmacokinetic implications for PFOA and PFOS chemical exposure.

Flame Retardants

Tris (1,3-dichloro-2-propyl) phosphate treatment induces DNA damage, cell cycle arrest and apoptosis in murine RAW264.7 macrophages.

The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study.

Pesticides

Mitigating effects of apigenin on edifenphos-induced oxidative stress, DNA damage and apoptotic cell death in human peripheral blood lymphocytes.

Whether warming magnifies the toxicity of a pesticide is strongly dependent on the concentration and the null model.

Increased daily temperature fluctuations overrule the ability of gradual thermal evolution to offset the increased pesticide toxicity under global warming.

Exposure to sublethal concentrations of methoxyfenozide disrupts honey bee colony activity and thermoregulation.

Herbal medicine against genotoxicity of dimethoate, an insecticide, in mammalian somatic cells.

Glyphosate affects haemocyte parameters in the clam Ruditapes philippinarum.

Quality survey and spatiotemporal variations of atrazine and desethylatrazine in drinking water in Quebec, Canada.

Arsenic/Metals

Gender Differences in Cardiac Remodeling Induced by a High-Fat Diet and Lifelong, Low-Dose Cadmium Exposure.

Microplastics

Response of bleached and symbiotic sea anemones to plastic microfiber exposure.

Uptake and effects of different concentrations of spherical polymer microparticles on Artemia franciscana.

Reproductive toxicity of primary and secondary microplastics to three cladocerans during chronic exposure.

Microplastic Ingestion by Gelatinous Zooplankton May Lower Efficiency of the Biological Pump.

Pharmaceuticals

Behavioral profile alterations in zebrafish larvae exposed to environmentally relevant concentrations of eight priority pharmaceuticals.

Mixtures

Growth stimulation effects of environmentally realistic contaminant mixtures on a marine diatom.

Miscellaneous

The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARγ in Adipogenesis: An in Vitro Study.

Wildlife/Environment/Exposure Studies

BPA

Knowledge, Attitude, and Behavior of Restorative, Orthodontic, and Pediatric Departments’ Members toward Bisphenol A Dental Exposures.

Persistent Organic Pollutants

Air monitoring of polychlorinated biphenyls, polybrominated diphenyl ethers and organochlorine pesticides in West Antarctica during 2011-2017: Concentrations, temporal trends and potential sources.

Proximity to chemical equilibria among air, water, soil, and sediment as varied with partition coefficients: A case study of polychlorinated dibenzodioxins/furans, polybrominated diphenyl ethers, phthalates, and polycyclic aromatic hydrocarbons.

Distributions and Sources of PAHs and OCPs in Surficial Sediments of Edremit Bay (Aegean Sea).

Age and seasonal variation in testis and baculum morphology in East Greenland polar bears (Ursus maritimus) in relation to high concentrations of persistent organic pollutants.

Comparison of trophic magnification factors of PCBs and PBDEs in Tokyo Bay based on nitrogen isotope ratios in bulk nitrogen and amino acids.

Monitoring dioxins and furans in plasma of individuals living near a hazardous waste incinerator: Temporal trend after 20 years.

Assessment of pops contaminated sites and the need for stringent soil standards for food safety for the protection of human health.

Perfluoroalkyl Substances

Associations between concentrations of perfluoroalkyl substances in human plasma and maternal, infant, and home characteristics in Winnipeg, Canada.

Flame Retardants

Intervention to reduce gymnast exposure to flame retardants from pit foam: A case study.

A simulation of the seasonal variation of decabromodiphenyl ether in a bay adjacent to the Yellow Sea.

Organophosphate flame retardants in total suspended particulates from an urban area of zhengzhou, China: Temporal variations, potential affecting factors, and health risk assessment.

Biomagnification of PBDEs and alternative brominated flame retardants in a predatory fish: Using fatty acid signature as a primer.

Analytical human biomonitoring method for the identification and quantification of the metabolite BDCPP originated from the organophosphate flame retardant TDCPP in urine.

A nationwide survey of 19 organophosphate esters in soils from China: Spatial distribution and hazard assessment.

Dietary exposure and risk assessment of exposure to hexabromocyclododecanes in a Taiwan population.

Pesticides

Residential mobility in early childhood and the impact on misclassification in pesticide exposures.

Comparative analysis of freshwater species sensitivity distributions and ecotoxicity for priority pesticides: Implications for water quality criteria.

Persistence of indoor permethrin and estimation of dermal and non-dietary exposure.

Bio-pesticide applications may impair the pollination services and survival of foragers of honey bee, Apis cerana Fabricius in oilseed brassica.

Arsenic/Metals

Urinary concentrations of environmental metals and associating factors in pregnant women.

Mercury exposure and altered parental nesting behavior in a wild songbird.

A systematic literature review for some toxic metals in widely consumed rice types (domestic and imported) in Iran: Human health risk assessment, uncertainty and sensitivity analysis.

Distribution and Speciation of Copper and Arsenic in Rice Plants (O.sativa japonica ‘Koshihikari’) Treated with Copper Oxide Nanoparticles and Arsenic during a Life Cycle.

Modulation of photosynthetic parameters, sugar metabolism, polyamine and ion contents by silicon amendments in wheat (Triticum aestivum L.) seedlings exposed to arsenic.

An uptake and elimination kinetics approach to assess the bioavailability of chromium, copper, and arsenic to earthworms (Eisenia andrei) in contaminated field soils.

Distribution, pollution status, and source apportionment of trace metals in lake sediments under the influence of the South-to-North Water Transfer Project, China.

Metal(loid) speciation in a river subjected to industrial anthropopressure: chemometric and environmental studies.

Organotins

Urinary trimethyl tin reflects blood trimethyl tin in workers recycling organotins.

Microplastics

Combined effect of polystyrene plastics and triphenyltin chloride on the green algae Chlorella pyrenoidosa.

Promising techniques and open challenges for microplastic identification and quantification in environmental matrices.

Identification, origin and characteristics of bio-bead microplastics from beaches in western Europe.

Evidence of microplastic accumulation in agricultural soils from sewage sludge disposal.

Miscellaneous

Prioritizing potential endocrine active high resolution mass spectrometry (HRMS) features in Minnesota lakewater.

An integrative assessment to determine the sediment toxicity of Kaohsiung Harbor in Taiwan: combining chemical analysis and cytotoxicity assay.

Micropollutants related to human activity in groundwater resources in Barbados, West Indies.

Occurrence and risk assessment of multiclass endocrine disrupting compounds in an urban tropical river and a proposed risk management and monitoring framework.

This list is not meant to be exhaustive, and generally does not include studies on detection, remediation, or treatment of EDCs. Note that journal publication dates may be different than dates added to PubMed. Compiled by Sarah Howard, Diabetes and Environment Program at Commonweal.

EHN EHN

Webinar: Fluoride, neurodevelopment, and cognition: a National Toxicology Program monograph
by Sarah Howard on November 19, 2024 at 5:00 pm
This Dec. 3 webinar features Dr. Kyla Taylor of NIEHS who will discuss the results of a National Toxicology Program monograph review that concluded there is "moderate confidence" in the scientific evidence that showed an association between higher levels of fluoride exposure and lower IQ in children.
Webinar: Behind the scenes at EPA: What's gone wrong and what does it mean for our work?
by Sarah Howard on November 19, 2024 at 3:56 pm
This Dec. 9 webinar, Behind the scenes at EPA: what's gone wrong and what does it mean for our work? is part 2 of a series on the future of EPA decision-making. Sponsored by the Collaborative for Health and Environment (CHE), Earthjustice, and UCSF's Earth Center.
Endocrine-disrupting chemicals: hazards and opportunities (ECHO) course
by Sarah Howard on October 31, 2024 at 2:50 pm
This course focuses on the chemical, biological, and societal challenges of endocrine-disrupting chemicals (EDCs) and new opportunities for moving forward. ECHO is a two-week intensive bootcamp-style career development course for graduate students, postdoctoral fellows, and professionals in the field. It is held at Woods Hole, Massachusetts.

EHN EHN

“We have enough evidence” to act on toxic plastic exposure now
by Katherine McMahon,Sarah Howard on November 22, 2024 at 3:31 pm
In a recent commentary published in The Lancet, Dr. Leonardo Trasande of NYU’s Grossman School of Medicine emphasizes the need to address the well-established health harms from exposure to chemical additives used in plastics. “Only through a serious and concerted effort to turn off the plastic tap will we apply the lessons learned from plastic use… and avoid the invisible chemicals used in plastic materials from becoming visible in the form of a larger global pandemic of chronic disease.”
Kids who adopt a gluten-free diet have increased arsenic levels
by Katherine McMahon,Sarah Howard on November 20, 2024 at 1:32 pm
A recent study published in The American Journal of Gastroenterology found that children who adopted a gluten-free (GF) diet after being diagnosed with celiac disease had significantly increased arsenic exposure after only six months. “More research needs to be done to determine whether there are long-term effects of this bump, but overall, I think it speaks to the importance of diversifying the grains in the gluten-free diet.”
NIEHS publishes new strategic plan
by Sarah Howard on November 19, 2024 at 6:03 pm
The National Institute of Environmental Health Sciences (NIEHS) published a 2025-2029 strategic plan, "Health at the Intersection of People and Their Environments."

EHN EHN

Trump’s second term could mean fewer protections for drinking water
by EHN Curators on November 21, 2024 at 12:30 pm
Donald Trump’s plans for the Environmental Protection Agency may include rolling back protections against PFAS and other drinking water threats, worrying public health advocates. Hiroko Tabuchi reports for The New York Times.
Kennedy’s fluoride policy faces obstacles
by EHN Curators on November 19, 2024 at 8:28 pm
President-elect Trump’s selection of Robert F. Kennedy Jr. to lead the Department of Health and Human Services won’t give him direct control over water fluoridation policies, though his influence could sway public and local debates. Miranda Willson reports for E&E News.
Scientists' Declaration for the Global Plastics Treaty
by Sarah Howard on November 19, 2024 at 5:54 pm
The signatories of this declaration are independent scientists with expertise on plastics, and who are free of conflicts of interest associated with the life cycle of plastics. Read it here and sign it here. Due Nov. 22, 2024.